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변압기의 유동대전에 대한 유속 및 유온의 영향에 관한 연구
정원용,고희석,박상현,박재윤,김정달 慶南大學校 附設 工業技術硏究所 1992 硏究論文集 Vol.10 No.-
本 硏究에서는 固體-液體 界面에서 液體가 流動할 때 발생되는 유동대전에 대한 硏究로서 大容量 變壓器내에서 絶緣油가 통과하는 通路를 모델링한 帶電 파이프를 設計·製作하고 대전 파이프내의 油路形狀에 따른 流動電流를 側定·分析하였다. 이러한 實驗으로부터 얻은 결과는 다음과 같다. 1) 流動電流는 油速의 增加에 따라 線形的으로 增加하였으며, 油溫의 增加에 따라 약 46[℃]이하에서는 增加하고 그 이상에서는 感少한다. 2) 絶緣油의 흐름이 원활하게 되도록 油路形狀을 변화시키면 流動電流는 感少한다. In this paper, the streaming electrification generated at a solid-liquid interface is studied. Electrification pipe modeled on the oil path of the high power transformer is designed and manufactured. The Streaming current is measured as a function of oil velosity, temperature at each electrification pipe. From the result of this study the following conclusions are obtained. 1) The streaming current increases linearly with increasing of oil velocity and It increases at lower temperature than 46[℃]and decreases at higher temperature than 46[℃] 2) The smoother the flow of insulating oil is the less the streaming current decreases.
Won-Seog Chong,Young-Soo Lee,Young-Jin Kang,Duck-Hyung Lee,Jae-Chun Ryu,Hye Sook Yun-Choi,Ki-Churl Chang 대한생리학회-대한약리학회 1998 The Korean Journal of Physiology & Pharmacology Vol.2 No.3
<P> Tetrahydroisoquinoline (THI) alkaloids can be considered as cyclized derivatives of simple phenylethylamines. Many of them, especially with 6,7-disubstitution, demonstrate a relatively high affinity for catecholamines. Present study examines the pharmacological action of limited series of THI, using rats isolated atria and aorta. In addition, a [<SUP>3</SUP>H] prazosin displacement binding study with THI compounds was performed, using rat brain homogenates to investigate whether these probes have -adrenoceptor affinity. We also compared the vascular relaxation potency of these probes with dobutamine. YS 49, YS 51, higenamine and dobutamine, concentration-dependently, relaxed endothelium-denuded rat thoracic aorta precontracted with phenylephrine (PE, 0.1 ㄍM) in which pEC<SUB>50</SUB> were 5.56⁑0.32 and 5.55⁑0.21, 5.99⁑1.16 and 5.57⁑0.34, respectively. These probes except higenamine also relaxed KCl (65.4 mM)-contracted aorta. In isolated rat atria, all THIs and dobutamine increased heart rate and contractile force. In the presence of propranolol, the concentration response curves of YS 49 and YS 51 shifted to the right and resulted in pA<SUB>2</SUB> values of 8.07⁑0.84 and 7.93⁑0.11, respectively. The slope of each compound was not deviated from unity, indicating that these chemicals are highly competitive at the cardiac -adrenoceptors. YS 49, YS 51, and higenamine showed -adrenoceptor affinity in rat brain, in which the dissociation constant (K<SUB>i</SUB>) was 2.75, 2.81, and 1.02 ㄍM, respectively. It is concluded, therefore, that THI alkaloids have weak affinity to <SUB>1</SUB>-adrenoceptors in rat aorta and brain, respectively, while these probes show relatively high affinity for cardiac -adrenoceptors. Thus, these chemicals may be useful in the treatment of congestive heart failure.
Won Seog Chong,Sun Young Kang,Young Jin Kang,Min Kyu Park,Young Soo Lee,Hye Jung Kim,Han Geuk Seo,Jae Heun Lee,Hye Sook Yun-Choi,Ki Churl Chang 대한생리학회-대한약리학회 2005 The Korean Journal of Physiology & Pharmacology Vol.9 No.5
Endothelium, particularly pulmonary endothelium, is predisposed to injury by reactive oxygen species (ROS) and their derivatives. Heme oxygenase (HO) has been demonstrated to provide cytoprotective effects in models of oxidant-induced cellular and tissue injuries. In the present study, we investigated the effects of YS 49 against oxidant [tert-butylhydroperoxide (TBH)]-induced injury using cultured sheep pulmonary artery endothelial cells (SPAECs). The viability of SPAECs was determined by quantifying reduction of a fluorogenic indicator Alamar blue. We found that TBH decreased cell viability in a time- and concentration-dependent manner. YS 49 concentration- and time-dependently increased HO-1 induction on SPAECs. As expected, YS 49 significantly decreased the TBH-induced cellular injury. In the presence of zinc protophorphyrin, HO-1 inhibitor, effect of YS 49 was significantly inhibited, indicating that HO-1 plays a protective role for YS 49. Furthermore, YS 49 showed free radical scavenging activity as evidenced by 1,1-diphenyl-2-picrylhydrazyl (DPPH) and inhibition of lipid peroxidation. However, YS 49 did not inhibit apoptosis induced by lipopolysaccharide (LPS) in SPAECs. Taken together, HO-1 induction along with strong antioxidant action of YS 49 may be responsible for inhibition of TBH-induced injury in SPAECs.
Chong, Won-Seog,Kang, Sun-Young,Kang, Young-Jin,Park, Min-Kyu,Lee, Young-Soo,Kim, Hye-Jung,Seo, Han-Geuk,Lee, Jae-Heun,ChoiYun, Hye-Sook,Chang, Ki-Churl The Korean Society of Pharmacology 2005 The Korean Journal of Physiology & Pharmacology Vol.9 No.5
Endothelium, particularly pulmonary endothelium, is predisposed to injury by reactive oxygen species (ROS) and their derivatives. Heme oxygenase (HO) has been demonstrated to provide cytoprotective effects in models of oxidant-induced cellular and tissue injuries. In the present study, we investigated the effects of YS 49 against oxidant [tert-butylhydroperoxide (TBH)]-induced injury using cultured sheep pulmonary artery endothelial cells (SPAECs). The viability of SPAECs was determined by quantifying reduction of a fluorogenic indicator Alamar blue. We found that TBH decreased cell viability in a timeand concentration-dependent manner. YS 49 concentration- and time-dependently increased HO-1 induction on SPAECs. As expected, YS 49 significantly decreased the TBH-induced cellular injury. In the presence of zinc protophorphyrin, HO-1 inhibitor, effect of YS 49 was significantly inhibited, indicating that HO-1 plays a protective role for YS 49. Furthermore, YS 49 showed free radical scavenging activity as evidenced by 1,1-diphenyl-2-picrylhydrazyl (DPPH) and inhibition of lipid peroxidation. However, YS 49 did not inhibit apoptosis induced by lipopolysaccharide (LPS) in SPAECs. Taken together, HO-1 induction along with strong antioxidant action of YS 49 may be responsible for inhibition of TBH-induced injury in SPAECs.
Hydroxyl Groups in Demineralized Bone Matrix
Seo, Seog Jin,Song, Seok Beom,Chae, Ji Hwa,Kim, Jin Young,Ahn, Jae Hyoung,Kim, Tae Woon,Hwang, Ho Chan,Kim, Jin,Lee, Kwang Won,Kang, Nak Heon,Cho, Chong Su,Kang, Ke Won Trans Tech Publications, Ltd. 2007 Key Engineering Materials Vol.342-343 No.-
<P>Human demineralized bone matrix (DBM) containing bone morphogenetic proteins (BMPs) is naturally biocompatible and can be remodeled by patients’ own bone. The major shortcoming of many of the currently used DBM gel formulations is that they have a tendency to flow, particularly if there is continuous bleeding at the application site. In this study, the physicochemical properties of human DBM were examined to improve the efficiency of DBM formulations. DBM remarkably showed higher water absorption than nondemineralized bone powder after 150 min. Hydroxyl groups in DBM appeared in fourier transform infrared analysis, although hydroxyl band in nondemineralized bone powder was not observed. The results suggested that hydrogels such as CMC, hyaluronic acid, or poloxamer as carriers can be applied for injectable DBM products, such as gel or putty types.</P>
박종원,강문원,신완식,김춘추,오용석,유진홍,김동집,김양리,한치화 대한내과학회 1995 대한내과학회지 Vol.49 No.4
Typhlitis is a life-threatening disease of bowel, mainly ileum or cecum, complicated in the immunocompromised hosts. Recently we experienced four cases of typhlitis in leukemic patients following cytotoxic chemotherapy. All the patients were diagnosed as acute myelogenous leukemia and received cytotoxic chemotherapy followed by granulocytopenia. They mainly showed fever, abdominal pain, and diarrhea. In one case, he suffered from intestinal obstruction. Abdominal CT showed diffuse thickening of ileocecal region or ascending colon. Stool culture revealed Staphylococcus aureus in two cases and Entercoccus species in one case. Staphylococcus aureus was isolated from blood culture in one case. They were managed medically and three out of four cases survived.
Ahn, Jun-Cheul,Chong, Won-Seog,Kim, Young-Soon,Hwang, Baik The Korean Society for Biotechnology and Bioengine 2006 Biotechnology and Bioprocess Engineering Vol.11 No.2
Saikosaponin productivity was examined in a Bupleurum falcatum L. BFHR2 hairy root culture in response to changes in the sucrose content $(2{\sim}8%)$, nitrogen content $(0{\sim}250mM\;NH_4NO_3)$, phosphate content $(0{\sim}12mM\;NaH_2PO_4)$, and the potassium content $(0{\sim}87.2 mM\; KCl)$ of the culture media. We found that the conditions for maximal saikosaponin production differed from those for optimal root growth. Highest saikosaponin yield was achieved for 8% sucrose, 62mM $NH_4NO_3$ 1.2 mM $NaH_2PO_4$, and 0.5mM KCl.