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윤정로,심재익,김택선,이성종,김영배,김학준,안국환,장재영,홍명표 대한골절학회 2002 대한골절학회지 Vol.15 No.4
쇄골 중간 1/3 부위의 골절은 치료 결과가 양호하여 보존적 치료가 원칙적으로 받아 들어지고 잇으며 불유합에 대한 빈도도 낮은 것으로 되어 있다. 그러나 최근 전위 및 단축의 정도가 심할 경우 높은 불유합의 결과와 불량한 임상 결과를 보고하고 있어 이런 예에 대해선 수술적 치료를 권장하고 있다. 저자들은 단축 및 전위의 정도와 불유합의 연관성을 알아보고자 하였다. 연구 대상 및 방법 : 1993년 2월부터 2002년 1월까지 본원에 내원 했던 성인 중간부 쇄골 골절 환자 194명 중 완전 전위를 보인 78례를 조사하여 이중 63례를 대상으로 분석하여 후 향적 연구를 시행하였다. 4개월 추시 후에도 방사성 사진상 유합 소견이 관찰되지 않으면 불유합의 유의성을 알아보고자 하였다. 결 과 : 63례 중 불유합 및 지연 유합을 소견을 보인 환자는 15(23%)례였다. 골유합을 보인 48례의 단축은 평균 8.6㎜(2㎜-17㎜)였고, 전위는 평균 9.7㎜(2-22㎜)였다 .불유합 및 지연 유합을 보였던 15례에서 단축은 평균 14.5㎜(3㎜-37㎜), 전위는 평균 17.3㎜(4-25㎜)였다. 18㎜이상 단축이 있었던 경우 불유합의 발생과는 통계학적으로 유의성을 나타내었고(Fisher's exact test, p<0.01), Chi-square test상 16㎜ 이상의 전위를 보였던 경우 불유합 발생과 통계학적으로 의미가 있었다(p<0.01). 결 론 : 쇄골 골절 특히 중간 1/3의 골절은 비교적 보존적 치료에 결과가 좋은 것으로 되어 있으나, 전위 및 단축이 심한 경우 불유합에 대한 가능성이 높이 때문에 보다 경과 관찰시 유합의 진행이 없으면 적극적인 치료를 고려해야한다. Purpose : Because the prognosis of the mid 1.3 clavicle fracture is good, the conservative treatment with a figure of 8 bandage is the gold standard and the nonunions are rare. However, recently surgical treatment is recommended when the shortening and displacement is severe because of the high nonunion rate and the poor clinical result. This study was undertaken to evaluate that the shortening and displacement at fracture site are associated with the development of nonunion. Materials and Methods : We analysed the 194 fractures of mid 1/3 clavicle in adults which had been treated conservatively from February 1993 to January 2002 and did the retrospective study. Of these, 78 cases were originally in the middle third of the clavicle and had been completely displaced. We reviewed 63 of these cases. The shortening and displacement at the fracture site was measured on the initial roentgenogram. And the analysis of the patients' chart was done for another predisposing nonunion factors. Nonunion and delayed union are considered to be present when there has been little or no progression of clinical or radiographic healing at a minimum of 4 months after injury. Results : 15 of the 63 cases had developed nonunion.. The average 8.6㎜(2㎜-17㎜) shortening and average 9.7㎜(2-22㎜) in the union patients. The average 14.5㎜(3㎜-37㎜) shortening and average 17.3㎜(4-25㎜) in the nonunion patients. We found that initial shortening ≥18㎜(Fisher's exact test, p<0.01) and initial displacement ≥ 16㎜(Chi-square test. p<0.01)at the fracture site were significantly associated with the development of nonunion. Conclusion : The conservative treatment with figure-80-bandage is the gold standard in the clavicle middle one third fracture. However, the nonunion is commonly occurs in the cases of more of severely shortened and displaced fractures. If there are no signs of callus formation and the patient complains of pain after several week, osteosynthesis should be considered.
Notes : Culture Conditions Affecting the Optimal Mycelial Growth of Cystoderma ami anthinum
( Sung Mi Shim ),( Yun Hee Oh ),( Kyung Rim Lee ),( Seong Hwan Kim ),( Kyung Hoan Im ),( Jung Wan Kim ),( U Youn Lee ),( Jae Ouk Shim ),( Mi Ja Shim ),( Min Woong Lee ),( Hyeon Su Ro ),( Hyun Sook Lee 한국균학회 2005 Mycobiology Vol.33 No.1
심상로(Sang Ro Shim),서진석(Jin Suk Suh) 한국가구학회 1994 한국가구학회지 Vol.5 No.1
This study was carried out under the assembly conditions at company and laboratory, for the purpose of acquiring the available adhesion-joint performance of wooden dowels which are being commonly used in jointing the furniture members.<br/> In laboratory assembly test, Polyvinyl acetate emulsion resin adhesive(room temperature curing type), urethane resin adhesive and MDI resin were applied to the dowels-joint of members of lumber, PB and MDF in a separate use or a mixed use condition, and then their withdrawal strengths were evaluated.<br/> Also, the withdrawal strengths were Investigated according to the elapsed time after gluing and assembly of dowels.<br/> There suits were summarized as follows:<br/> 1. The withdrawal strength was highest at the lowest diameter 6mm of dowel of tested 6, 8 and 10mm at each member in the company assembly condition.<br/> 2. In the laboratory assembly condition, the lumber showed the highest withdrawal strengths, which were subordinated with those at PB and MDF, resulting in th ε almost same withdrawal strengths between two members.<br/> 3. According to the types of adhesive and their formulations, th ε withdrawal strengths by urea resin and urethane resin at both separate use and mixed use condition were higher, comparing to that by a single use of poly vinyl acetate resin adhesive.<br/> 4. In terms of the developing speed of withdrawal strength by the elapsed time after gluing and assembly of dowels, there was a nearly proportional increase until 24 hrs. after assembly at lumber. On the contrary to this, there was a mild increase until about 6hrs. after assembly at PB and MDF, and there after no difference until 24 hrs.<br/> 5. From the above results, it was suggested that th ε handling and conveying of dowels-assembled furniture to other processing or finishing line , if at least 6 hrs. elapse after assembly of dowels at members, can not affect much the withdrawal strengths. Particularly, a good joint strength in this case was obtained with<br/> application of urethane resin mixed- urea resin a adhesive.
노환성,최상희,정재심,배직현 울산대학교 의과대학 1993 울산의대학술지 Vol.2 No.2
A 0.5% chlorhexidine gluconate in 70% isopropyl alcohol tincture(H-Tincture) has been shown to be highly efficacious for skin disinfection and is used widely in hospitals as a skin cleansing agent for patients and health-care personnel. However, the optimum and the most cost effective combination of two disinfectants is net known. we examined the bactericidal effect of chlorhexidine gluconate and isopropyl alcohol singly or in combination at various concentrations against clinical isolates of Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa. Pure cultures of the test organisms were incubated in disinfectant solutions for up to 15 minutes and 0.01 ml aliquots were cultured in broth for viability. Chlorhexidine gluconate solutions alone at the concentration of 0.5% and 0.1% were as bactericidal as in combination with isopropyl alcohol at various concentrations. The most cost-effective combination of the two disinfectants was shown to be 0.05% chlorhexidine gluconate in 30% isopropyl alcohol. These results suggest that the concentrations of chlorhexidine gluconate and isopropyl alcohol could be reduced from the current formula of H-Tincture without compromising its antimicrobial activity and warrant further studies in clinical setting to define the most cost-effective combination of the disinfectants.
A De Novo Centric Fission of Chromosome 11 in a Patient with Recurrent Miscarriages
Shim, Sung Han,Lee, Cheol-Hoon,Lee, Ji-Yeon,Shin, Eun-Sim,Kyhm, Jee Hong,Park, Moon-Il,Chung, Sung-Ro,Cho, Youl-Hee The Korean Academy of Medical Sciences 2007 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.22 No.1
<P>We report on a <I>de novo</I> centric fission of chromosome 11 in a healthy female referred for chromosome analysis due to recurrent miscarriages. Both fission products were mitotically stable. This centric fission of chromosome 11 appears to have no clinical significance for this patient other than recurrent miscarriages.</P>
The CTG repeat polymorphisms of myotonic dystrophy (DM) gene in Korean population
Shim, Sung-Han,Cho, Youl-Hee,Choi, Soo-Kyung,Chung, Sung-Ro Korean Society of Medical Genetics 1997 대한의학유전학회지 Vol.1 No.1
Myotonic dystrophy (DM) is caused by the expansion of CTG trinucleotide repeat near the 3' end of the gene encoding for a member of protein kinase gene family (DMPK). The normal range of the CTG repeat was determined in 178 normal individuals (141 unrelated individuals and 37 of 9 families) by polymerase chain reaction (PCR), polyacrylamide gel electrophoresis and silver staining method. And the expansion of the CTG repeats in a DM family was analyzed with Southern analysis. In normal population, the range of CTG repeat is between 5 and 34 and 19 different alleles were observed in that range, and $(CTG)_{11-14}$ alleles were predominant. 4 members of an affected family showed the 0.5-2.0 kb size expansion of CTG repeats. In this study we could predict the incidence of DM in Korea as 1 in 20,000 and we could establish the diagnostic procedure for myotonic dystrophy.