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      • 부산 신항의 철도물류 활성화 방안

        조삼현,김익희 동의대학교 경제경영전략연구소 2012 經濟經營硏究 Vol.7 No.1

        Rail transportation system are needed to develop proper corresponds to satisfy various demands in freight transportation since there are many problems in rail transportation infrastructure and operation. This paper analyzes characteristics of rail transportation shipper and develops policy for vitality of rail transportation by survey of rail transportation shipper in Busan new Port. This paper is organized as follows. Section 1 presents the description of the objective and the methods for this study. Section 2 presents the operation situation and container volumes in Busan port. Section 3 presents the forcasting volume of Busan port and rail freight transportation. Section 4 presents the Several Problems and solutions through analysis the rail transportation shipper. Section 5 summarizes conclusions and discusses further research topics.

      • Cycloheximide가 Mouse肝臟의 인산염 分解酵素의 活性에 미치는 影響

        趙賢熙,鄭鎬三,李圭植 漢陽大學校 環境科學硏究所 1985 環境科學論文集 Vol.6 No.-

        Cycloheximide는 Streptomyces griseus에서 추출한 항진균성 항생제로 진균의 성장을 저해하는 물질로 알려져 왔으며 포유동물의 세포에서 ribonucleic acid와 단백질 합성을 저해한다고 생화학적 방법에 의하여 보고되었다. 최근에 이르러 cycloheximide의 투여로 간세포내 소기관인 조면내형질세망 및 Golgi complex의 손상에 의해서 단백질합성이 저해된다고 형태학적으로 연구 보고된 바 있다. 이와같은 cycloheximide의 투여로 간세포가 손상을 입어 단백질합성이 저해될 때 간세포내 인산염분해효소로 분포되어 있는 acid phosphatase와 adenosine triphosphatase 활성을 추구하였다. 실험동물로는 실험실에서 사육한 건강한 ICR계 체중 20∼30gm의 mouse를 사용하였으며 정상대조군과 cycloheximide 투여군으로 구분하고 실험군은 다시 cycloheximide 투여 후 6시간군, 12시간군, 24시산군 및 36시간군으로 나누었고 각군에 10마리씩 배정하였다. Cycloheximide는 mouse의 체중 ㎏당 4㎎ 되게 생리적 식염수에 용해하여 0.1㎖를 복강내에 투여후 6시간, 12시간, 24시간 및 36시간 후에 희생시켜 간장을 적출하고 10% neutral formalin에 고정한 다음 cryostat로 두께 15㎛ 되게 동결절편을 만들어 Gomori법으로 acid phosphatase활성과 Wachstein 및 Meisel법으로 adenosine triphosphatase 활성을 관찰한 결과 다음과 같은 결과를 얻었다. 1. Cycloheximide 투여후 6시간, 12시간군 및 24시간군의 mouse 간소엽에서 중심 정맥부로 부터acid phosphatase 활성이 증가되기 시작하여 36시간군에서는 간소엽 전역에 중등도 이상의 강한 활성이 관찰되었다. 2. Cycloheximide 투여후 24시간군에서 부터 간소엽의 중심 정맥부에 ATPase 활성이 감소되기시작하여 36시간 경과군에서는 간소엽 전역에 음성반응을 나타내었다. 상기와 같은 결과는 cycloheximide 투여로 간장의 acid phosphatase는 간장이 손상을 입을 때 그 활성이 보다 강한 양성반응을 보이고 adenosine triphosphatase는 역으로 활성이 약해진다고 사료된다. It has been knwon that cycloheximide, an antifungal antibiotics extracted from streptomyces griseus, inhibits the growth of fungus. It has been reported by several investigators that this drug inhibits ribouncleic acid activity and protein synthesis of the mammalian cell. Recently, several reporters indicated that the cycloheximide causes the damage of hepatocyte. The observations by electron microscopic, histochemical and histological studies revealed that cycloheximide inhibits the RNA and protein synthesis by the injury of rough endoplasmic reticulum and the desocciation of polysome in hepatocyte. This study attempted, on the activities of acid phosphatase adenosine triphosphatase, phosphatelysis-enzymes distributed in the hepatocytes in the mouse liver. Healthy albino mice(ICR strain) of 20gm±in body weight were used as experimental animals which were divided into the control and cycloheximide treated groups. The animals of the cycloheximide treated groups were administered cycloheximide. (dissolved in physiological saline sol., by intraperitoneal injection in a dose of) 4mg per kg of body weight in a volume of 0.1ml, intraperitoneally. The experimental animals were sacrificed at intervals of 6, 12, 24 and 36 hours after administration of cycloheximide, respectively. The liver specimens were fixed with 10% neutral formalin, the sections of 15㎛ thickness were stained by Gomori, Wachstein and Meisel`s method for the detection of acid phosphatase and adenosine triphosphatase activities. The results were obtained as follows; 1. Acid phosphatase activity was increased in the central zone of liver lobule at the 6 hour and 24 hour period of the cycloheximide treated group, moderately positive activity was showed in the liver lobule at the 36 hour period group. 2. Adenosine triphosphatase activity was decressed in the centrol zone of liver lobule at the 24 hour period of the cycloheximide treated group. Negative reactions were showed in the whole liver lobules at the 36 hour period group. Consequently, it is supposed that cycloheximide caused increase of liver acid phosphatase result from liver damage, while adenosine phosphtase activity of the liver was decreased.

      • KCI등재

        파노라마방사선사진 지수와 임플란트 실패와의 관계에 관한 연구

        조현정,이원진,허민석,안창현,이진구,이삼선,최순철 大韓口腔顎顔面 放射線學會 2004 Imaging Science in Dentistry Vol.34 No.1

        Purpose : Several panoramic indices have been suggested to assess bone quality from the morphology and width of mandibular cortex on panoramic radiography. The purpose of this study was to compare dental implant failure group with control group in panoramic mandibular index (PMI), mandibular cortical index (MCI), and gonion index (GI) and to determine the effect of these panoramic indices on dental implant failure. Materials and Methods : A case-control study was designed. Test group (n = 42) consisted of the patients who had their implants extracted because of peri-implantitis. Control group (n = 139) consisted of the patients who retained their implants over one year without any pathologic changes and had been followed up periodically. They had dental implants installed in their mandibles without bone augmentation surgery from 1991 to 2001. The following measures were collected for each patients: 1) PMI, MCI, and GI were measured twice at one-week interval on preoperative panoramic views; and 2) age, sex, implant length, implant type, installed location, occluding dentition state, and complication were investigated from the chart record. Results : The PMI showed moderate level of repeatability. The intra-observer agreement of MCI and GI were good. There was statistically significant difference in PMI between two groups. There were significant different patterns of distribution of MCI and GI between two groups. Among the panoramic indices, PMI and MCI showed significant correlation with dental implant failure. Conclusion : Panoramic indices can be used as reference data in estimating bone quality of edentulous patients who are to have implants installed in their mandibles.

      • 公州 錦江 流域의 청둥오리 Anas platyrhynchos 와 쇠오리 Anas crecca의 行動 樣式 比較

        趙三來,金賢泰 공주대학교 사범대학 과학교육연구소 1992 과학교육연구 Vol.23 No.1

        Mallards(Anas platyrhynchos) and Green-Winged Teal(anas crecca) were studied at Kum River, Kongju, Korea, from 29, December, 1990 to 5, Janury, 1991. There was a wide difference between Mallards(Anas platyrhynchos) and Green-Winged Teal(Anas crecca) in body length but used to same Resting or Feeding area. Resting time was the major activity of mallards(43-45%) and Feeding time was the major activity of Green-Winged Teal(30-34%). Both species increased Resting time as approach of sunset but Locomotion and Comfort decreased. Locomotion(22-24% and 16-24%) and Comfort(16-21% and 14-22%) also were dominant behavioral activities of Mallards and Green-Winged Teal, respectively. Total time spent in Alert, Courtship and Agnoistics behavior was low for both species(>3%). Mallards and Green-Winged Teal rested most on sand bar in River side, while paddy fields were used most for feeding area.

      • 부인과 영역에서의 내시경

        조삼현 한양대학교 의과대학 2000 한양의대 학술지 Vol.20 No.1

        Today, endoscopy has revolutionized the practice of gynecology. It has modified the thinking, approach, diagnostic ability and operative capability of gynecologist, and make an enhancement of the skills of gynecologist far beyond anyone's expectations in parallele with the application of the ultrasonography. This revolution has been flourished with the in vitro fertilization(IVF), and further used without big problem during pregnant state. Modern optics and high-powered light sources are now efficient that the diameter of endoscope has been reduced without loss of definition. This has allowed the development of narrow telescope which can be inserted via a laparoscope into the ampulla of the Fallopian tube. Salpingoscopy is already providing a clear understanding of pathology in the tube. However, this brilliant apparatus and application have been blockaded totally by the medical insurance system in our country. This sorrowful happening makes a regression of medical development in Korea.

      • SCOPUSKCI등재

        흉배혈관의 근피 천공분지에 기초한 유리피판의 임상적 이용

        조규성,김대영,안호범,이삼용,조백현 大韓成形外科學會 1999 Archives of Plastic Surgery Vol.26 No.3

        The latissimus dorsi muscle or musculocutaneous flap is one of the most useful flaps in reconstructive surgery. This flap has many advantages, such as its reliable anatomy, long pedicle with large caliber vessels, minimal functional deficit of the donor site, and low incidence of donor site complications. However, the bulkiness of the flap has been considered a disadvantage, so various modifications of technique have been devised. The cutaneous portion of the flap can be safely elevated based on the cutaneous perforating branch of the thoracodorsal vessel. From March 1997 to February 1998, 10 patients underwent reconstructive procedures with thoracodorsal perforator-based free flaps. The composition of the flaps varied in accordance with the nature of the defect. The variances in the flaps were as follows; 3 were cutaneous, 6 musculocutaneous, and 1 osteomusculocutaneous including the rib. All flaps survived with good contour. We concluded that this thin and reliable flap was useful for reconstruction of various defects, and that the composition of the flap, such as subcutaneous, muscle and bone, gave it considerable flexibility as needed.

      • 진해시 웅산-장복산 지역의 등산로변 수목조사

        추갑철,조현서,박삼봉,김병부 진주산업대학교 산업과학기술연구소 2006 산업과학기술연구소보 Vol.- No.13

        진해시 웅산 - 장복산 지역의 등산로 5구간(Ⅰ: 웅산 ~ 안민고개, Ⅱ: 천자봉 ~ 웅산, Ⅲ: 자은초등학교 ~ 시루봉, Ⅳ: 안민고개 ~ 청룡암, Ⅴ: 안민고개 ~ 장복산)의 목복식물을 조사한 결과 47과 76속 100종 11변종 6품종이로 총 117종류가 조사 되었다. 이들 중 상록침엽수는 소나무, 해송, 리기다소나무, 잣나무, 삼나무, 화백, 편백, 둥근향나무 등 8종류이고, 상록활엽수는 남천, 사철나무, 은목서, 마삭줄, 동백, 차나무, 후피향나무 등 7종류이며, 희귀 멸종 식물은 산닥나무가 조사되었다. 한국 특산종으로는 잣나무, 노각나무, 신이대, 오동나무 등이 조사 되었다. 전 구간에 걸쳐 나타나는 수종으로는 소나무, 해송, 리기다소나무, 편백, 상수리나무, 떡갈나무, 졸참나무, 신갈나무, 팽나무, 비목, 벚나무, 자귀나무, 조록싸리, 진달래, 싸리 등 15종류였다. The woody plants species were investigated as 117 taxa; 47 families, 76 genus, 100 species, 11 varieties, 6 forms in whole 5 trails surveyed areas of the region from Ungsan to Jangbogsan in Jinhae(Ⅰ; Ungsan~Anmingogae, Ⅱ; Cheunjabong~Ungsan, Ⅲ; Jaeunchogyo~Sirubong, Ⅳ; Anmingogae~ Cheangryongam, Ⅴ; Anmingogae~Jangbogsan). The narrow-leaved evergreen types were 8 species; Pinus densiflora, Pinus thunbergii, Pinus koraiensis, Pinus rigida, Cryptomeria japonica, Chamaecyparis obtusa, Chamaecyparis pisifera and Juniperus chinensis var. globosa. The broad-leaved evergreen types were 7 species; Nandina domestica, Euonymus japonica, Osmanthus asiaticus, Trachelospermum asiaticum var. intermedium, Camellia japonica, Thea sinensis and Ternstroemia japonica. The endemic woody in korea were Pinus koraiensis, Stewartia koreana, Sasa coreana and Paulownia coreana. The rare and endangered species was Wikstroemia trichotoma. In all area surveyed woody plants were Pinus densiflora, Pinus thunbergii, Pinus rigida, Chamaecyparis obtusa, Quercus acutissima, Q. dentata, Q. serrata, Q. mongolica, Celtis sinensis, Lindera erythrocarpa, Prunus serrulata var. spontanea, Albizzia julibrissin, Lespedeza maximowiczii, Rhododendron mucronulatum and Lespedeza bicolor.

      • SCOPUSKCI등재

        기저세포암 및 편평세포암에서 미세혈관밀도와 p53 단백 발현에 관한 연구

        어수락,조규성,안호범,김대영,이삼용,조백현 大韓成形外科學會 1999 Archives of Plastic Surgery Vol.26 No.3

        Basal cell carcinoma(BCC) and squamous cell carcinoma (SCC) are very prevalent neoplasms of the human skin. Ultraviolet radiation in sunlight is a well-established mutagen of the p53 gene and is one of basal cell carcinoma and squamous cell carcinoma. The newly-formed vascular network is important for neoplasms to grow beyond a size of about 1 ㎣. Recent reports have suggested the hypothesis that a mutant p53 protein is closely related with capillary density. Immumohistochemistry for p53 protein and CD34 was performed in 20 cases of BCCs and 14 SCCs to evaluated the relationship between p53 protein and capillary density. The results were as follows:1. The microvessels stained by CD34 were mainly located in the interface of tumor cells and stroma. 2. There was no difference in the microvessel density according to the histologic types and age of the patients, but a higher microvessel density was noted in male patients. 3. The aggressive BCCs and the less-differentiated SCCs showed higher p53 immunostaining. 4. The mean microvessel density of cases showing strong positive immunostaining of the p53 gene(54.73±17.75) was higher than that of others(39.75±18.30). These results suggested that p53 protein expression and microvessel density are not related to the histologic types and age of the patients, but that differentiation and biologic behavior such as the infiltrating property of tumors and the microvessel density are closely related to p53 protein expression.

      • Bacillus thuringiensis var. darmstadiensis 와 var. sotto의 내독소와 Bacillus thuringiensis var. kurstaki가 생산하는 아밀라제의 연구

        이형환,김삼찬,황광현,임창로,조용칠,정인명 건국대학교 교육대학원 1991 敎育論叢 Vol.15 No.-

        Endotoxin crystals produced by B.thuringiensis var. darmstadiensis cultured in modified GYS medium over 72 h were ovoidal in shape and separated using Renografin gradient centrifugation. The crystal protein bands were observed. When B.thuringiensis var sotto was grown in the modified GYS broth, it entered stationary phase at 8-9 h after inoculation. Proteinaceous crystals were banded at the position in 40% of Renografin gradient. The solubilized crystal proteins were formed by two bands, 130 Kd and 68 Kd in the SDS-PAGE. One plasmid was observed in B.thuringiensis var darmstadiensis and no plasmid in var. sotto in this study. Enzyme activity of amylase produced B.thuringiensis var kurstaki strain in the basal medium was 0.4 units per ml, and was enhanced to 0.6 units per ml in the basal medium contained soluble starch, Ca^++, Mg^++ and Mn^++ ions. Amylase production medium containing soluble starch was suitable for the amylase production and the highest activity appeared at 4-6 h after cultivation at 32℃. The amylase activity obtained by ethanol precipitation was 0.20 units per ml in 0.1 M phosphate buffer. The band of the molecular weight of 50 Kd was observed by SDS-PAGE analysis. Km value of the amylase for the soluble starch was 6.80 mg per ml.

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