정신분열병 하위집단에서의 지속적 중의 장애

신수경,한양순,한은선,이종국 용인정신의학연구소 1998 용인정신의학보 Vol.5 No.1

주변 자원과의 연계를 통한 명심체험마을의 발전방향

이태순,김은영,윤성수,리신호 忠北大學校 農業科學硏究所 2012 農業科學硏究 Vol.28 No.2

The MYEONGSIM village located in Baekkok-myeon, Jincheon-gun, Chungcheongbuk-do, Korea has been developed the green tourism, farm stay and green rural experience project. Although the village has more varius advavtages such as gacilities and experience program than the other villages its tourists are gradually decreasing. In this thesis, specific development direction of the village will be proposed by the analysis of characteristics of tourists and SWOT analysis through understanding of characteristics of visitors and investigation of rural amenith resources

Cam-Follower 기구의 단순형상변형 설계에 의한 기구학적 성질의 변화에 관한 연구

최은순,신중호 國立 昌原大學校 産業技術硏究所 1992 産技硏論文集 Vol.6 No.-

As direct contact mechanisms, Cam-follower mechanisms are used commonly. Disk-typed cams have 4 different types due to the different type of followers, such as reciprocating roller type, reciprocating flat type, oscillating roller type, and oscillating flat type. In this paper, iterative contact method is used to design the cam shapes and analyze the kinematic properties of the cam and follower mechanisms. For the given displacements, the shapes of cam must be designed accurately with the given types of the follower. But Engineers in domestic industry modify the type of followers by simple shape synthesis without consideration of functional aspects. This paper presents that the simple shape modification as the reverse design makes big trouble in machines the mechanism operates incorrectly.

췌장암 환자에서 알코올 내장신경 신경파괴블럭 후 발생한 간염

이상은,최석환,김영환,임세훈,이정한,이근무,정순호,최영균,김영재,신치만 인제대학교 2008 仁濟醫學 Vol.29 No.-

Splanchnic neurolytic block(SNB) with alcohol improves the management of pancreatic cancer pain. Adverse effects of alcohol SNB which include regional pain, hypotension, diarrhea, and acute alcohol intoxication are common, but acute hepatitis caused by alcohol neurolytic block is rare. A 63-year-old patient with pancreatic head cancer and liver metastasis had complete pain relief after both retrocrural tansdiscal SNB with 100% alcohol 10 ml. But, 1 day later, liver function test showed a high elevation in the aspartate aminotransferase (AST, 2182 IU/L) and alanine aminotransferase (ALT, 1807 IU/L). The patient had slight jaundice, general weakness, chilling, nausea and vomiting after SNB. Both AST and ALT decreased to 46 and 119 IU/L within 10 days with only supportive therapy. But, 19 days later, the patient died due to pneumonia. Our case illustrates the importance of clinical surveillance especially in patient with hepatic disease after alcohol SNB.

신원방우황청심원액의 뇌허혈 및 중추신경계에 대한 약효

조태순,이선미,이은방,조성익,김용기,신대희,박대규 성균관대학교 약학연구소 1999 成均藥硏論文集 Vol.11 No.-

Abstract-In order to investigate pharmacological properties of New Wonbang Woohwangchungsimwon Liquid(NSCL) and Wonbang Woohwangchungsimwon Liquid(SCL), the effects of NSCL and SCL on cerebral ischemia and central nervous system were compared. Cerebral ischemia insult was performed using unilateral carotid artery occlusion in mongolian gerbils. The histological observations showed a preventive effect of NSCL and SCL treatments with ischemia-induced brain damage. The ATP in brain tissue was decreased in vehicle-treated ischemic gerbils. This decrease was prevented by NSCL and SCL treatment. In contrast to what was seen with ATP, lipid peroxide were elevated in vehicle-treated ischemic gerbils. This elevation was inhibited by NSCL and SCL treatments. While NSCL and SCL had no effects on the hexobarbital-induced sleeping time, they showed sedative effect in rotarod and spontaneous activity test. NSCL and SCL prevented the seizures induced by electric shock and strychnine, but the effect of NSCL was less than that of SCL. Furthermore, NSCL and SCL showed anti-stress effect. Our findings suggest that the phamacological profiles of NSCL on cerebral ischemia and central nervous system are similar to those of SCL.

牛乳및 乳製品中의 異種脂肪 檢出에 關한 硏究

정은자,이용억,김을상,신광순 韓國營養學會 1978 Journal of Nutrition and Health Vol.11 No.2

The ice cream, a type of freezing food of condensed state of milk, richer in nutritions and easily available in all seasons, is one of luxuary items. The fatty acids in the milk is the most important component of ice cream which not only improve the nutritional value but also is easier digestive, more rapidly absorbed than those of plant and also has influence up the quality of the goods. In order to see the fatty acid distribution of the fats in the ice cream on the market, the ice creams on the market were selected in accordance with things most in demands of each manufacture divided into the shape. and analyzed for the concentration of total lipid, acid value, iodine value and saponification value. For the compositional analysis of fatty acid of milk as basis and those gas liquid chromatography was also used. The following were the results obtained. 1) The average total lipids in milk and, the 3 kind of ice creams shaped carton, cone and bar were 3.04, 8.34, 6.41, and 5.4% respectively. 2) The average acid values of milk and each of 3-different type of ice creams shaped carton, cone and bar were 0.72, 0.62, 0.76, and 0.95 respectively. 3) The soponification values. Ranged from 180 to 260, varied great degree depending upon. the different manufactures, the average saponification value of the milk and each type of ice cream shaped carton, cone and bar were 208, 226, 226 and 215 respectively. 4) The iodine values varying great degree upon the different manufactures ranged from 10 to 32, the average values of milk and each type of ice cream shaped carton, cone and bar were 29, 20, 19 and 22 respectively. 5) The fatty acids analyzed for milk and ice cream, were 17-different kind, for the milk palmitic acid appeared principal constituents which valued 29.8%, whereas oleic acid were 27.1%. Since the compositions of fatty acid in ice creams for each different manufacture varied so great degree from manufacture to manufacture that the average values of those for the same shaped ice creams seems to have no meaning, if the compositions of fatty acid in the ice cream were considered according to the manufactures such as A, B, C, D and E companies. 27.4% lauric acid which was principal constituents, 17.8% palmitic acid and 11.8% oleic acid which was equal to 1/2 of that in the milk were found in the product of A company, 28.2% oleic acid and 27.8% palmitic acid which had similar pattern with the composition as that of milk in the product of B company, 25.5% palmitic acid, 22.7% oleic acid and 11.6% lauric acid in the product of C company, 34.4% lauric acid, 15.6% palmitic acid and 8.6% oleic acid which amounts to 1/3 of that in the milk in the product of D company, and 24.6% lauric acid and 18% palmitatic acid in the product of E company respectively. For the ratio of saturated to unsaturated fatty acid, these were 84 : 16 in the product of At 62 : 38 in the product of B, 68 : 32 in the product of C, 88 : 12 in the product of D, 79 : 21 in the product of E respectively, while this ratio for milk was 63 : 37. Although the compositional characteristic of fatty acids in the ice creams varied great degree according to the manufactures, all kinds of different shaped product showed the same pattern in composition regardless of the type of ice cream shaped in provided they were made in the same company. The lauric acid was more exuberant, however oleic acid, unsaturated fatty acid, was of less quantity than in the milk fat. In general, there was less quantity of unsaturated fatty acid in the ice creams compared with in milk.

신원방우황청심원의 뇌허혈 및 중추신경계에 미치는 영향

조태순,이선미,이은방,조성익,김용기,신대희,박대규 성균관대학교 약학연구소 1999 成均藥硏論文集 Vol.11 No.-

Abstract-In order to investigate pharmacological properties of New Wonbang Woohwangchungsimwon Pill(NSCH) and Wonbang Woohwangchungsimwon Pill (SCH), the effects of NSCH and SCH on cerebral ischemia and central nervous system were compared. Cerebral ischemia insult was performed using unilateral carotid artery occlusion in mongolian gerbils. The histological observations showed preventive effects of NSCH and SCH treatments with ischemia-induced brain damage. The ATP in brain tissue was decreased in vehicle-treated ischemic gerbils. This decrease was prevented by SCH treatment. In contrast to what was seen with ATP, lipid peroxide were elevated in vehicle-treated ischemic gerbils. This elevation was inhibited by NSCH and SCH treatments. While NSCH and SCH had no effects on the hexobarbital-induced sleeping time, they prevented the seizures induced by eletric shock and strychnine. NSCH and SCH showed sedative effect in rotarod and spontaneous activity test. Furthermore, NSCH and SCH showed anti-stress effect. Our findings suggest that the pharmacological profiles of NSCH on cerebral ischemia and central nervous system are similar to those of SCH.

전기경련요법에서 remifentanil이 혈역학에 미치는 효과

정순호,이상은,임세훈,이정한,이근무,최영균,김영재,신치만 白中央醫療院 2005 仁濟醫學 Vol.26 No.1

Objective: Electroconvulsive therapy (ECT) is often associated with transient hypertension and tachycardia. Acute hemodynamic change may produce serious complications. Remifentanil is a potent ultra short acting opioid and has been found to reduce blood pressure and heart rate. The goal of this study was to evaluate effects of remifentanil on seizure duration, recovery parameters and hemodynamic changes during ECT. Methods: Ten ASA Ⅰ, Ⅱ patients enrolled in this prospective, randomized trial, each receiving more than four electroconvulsive therapy. Patients were randomized to receive placebo, group P (propofol 1mg/kg+0.9% normal saline 1ml, n=10), and propofol with remifentanil, group R (propofol 1mg/kg+remifentanil 1ug/Kg n=10). Supplemental dose of propofol was given as required to achieve loss of consciousness. We recorded hemodynamic parameters, seizure duration, and recovery parameters. Results: Seizure duration and recovery parameters were similar in group R and group P. Blood pressure and Hear rate after ECT were significantly lower in group R. Conclusions: Remifentanil(1ug/kg) attenuated the acute hemodynamic response to ECT under propofol anesthesia without adversely affecting the duration of seizure activity and recovery profile. Adjunctive use of remifentanil may be good alternative regimens for ECT.

1,2-벤조디아진-3-카복서마이드 유도체 합성 및 진통작용

권순경,송윤신,장은성,이명숙 德成女子大學校 藥學硏究所 1997 藥學論文誌 Vol.8 No.1

Seven new 7-H(or bromo)-4-hydroxy-2H(or methyl)-N-(5-aralkyl-3-aminohydantoinyl) -1,2-benzothiazine-3-carboxamide-1,1-dioxide derivatives were synthesized through the condensation of 7-H(or bromo)-4-hydroxy-2H(or methyl)-1,2-benzothiazine-3-carboxylic acid methyl ester 1,1-dioxides with 5-substituted-3-aminohydantoins. The analgesic activities of the synthesized compounds were investigated by Randall-Selitto assay. Most compounds exhibited lower activities but compound 6 and 7 showed higher analgesic activities than piroxicam.

밝은社會를 指向하는 指導者 Leadership에 關한 硏究 : 새마을 指導者를 중심으로 With Reference to the Saemaeul Leadership

朴淳永,申大淳,趙萬濟,金旭卿,金種垠 慶熙大學校 1980 論文集 Vol.10 No.-

The Saemaeul Undong was launched in 1972 on the basis of the experimental model or Saemaeul pilot projects of the previous year. The Saemaeul Undong is now a nation-wide movement which is based on the fundamental spirits of diligence, self-help and cooperation. Much of the success of the Saemaeul Undong depends on its leaders, who play a pivot role in implementing Saemaeul projects for their community. Popularly elected by the village assembly according to their leadership and faith, the leaders render their services without remuneration, working in the spirit of self-sacrifice. Now, the Saemacul Undong enters upon its tenth year in 1981. If the movement is to continue with renewed momentum, effective training projects for Saemaeul leaders must be worked out. For this purpose, it is then recommended that the research works on the leadership training projects of the Bright Society Movement be referred to. Initially started as a community movement for better life on the campus of Kyung Hee University in 1960's, the Bright Society Movement is now gaining widespread support from national as well as international club members. The goals of the Bright Society Movement are to promote mutual understanding and friendship among members and to construct on earth a truly sound and civilized welfare society that is spiritually beautiful, materially affluent, and humanely rewarding. The main objectives of this study is to propose effective training projects for Saemeaul leaders as well as the Bright Society leaders. 1) Educational courses of leadership training should be offered through the school as well as through the training institution of the community. 2) Educational contents of leadership training should place greater emphasis not only on the spiritual education but also on the technical and practical education related to the welfare of the Community. 3) Public relations education should be strengthened because leaders must work in close cooperation with the community residents for the effective movement. 4) Long-term integrated projects for the community or village unit should be established and the movement should be developed according to them. 5) A special system of regional itinerant education should be established for the effective management of selective leaders. 6) For the welfare of leaders themselves, special favors such as the authorization of leadership careers, scholarships for their sons and daughters, discounts on public charges and the priority on public employment must be offer according to their respective performance.