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韓國産 植物凝集素 Dolichos lablab L.의 免疫血淸學的 性狀에 關한 硏究
盧時憲,文國鎭 고려대학교 의과대학 1983 고려대 의대 잡지 Vol.20 No.3
Extracts of Korean Dolichos lablab L. were prepared in the usual manner, thereafter test of the agglutination with human whole blood and of agglutinating inhibition by human sera were carried out to clear of immunological characteristic of phytagglutinin, D. lablab L. Kim et al. reported that human washed red blood cells (RBC) was divided into agglutinating group(DL(+)) and not agglutinating group(DL(-)) by extracts of D. lablab and that the frequency of D(+) group was 98% and of D(-) group was 2%. In this study, it was demonstrated that some human whole blood were agglutinated by D. lablab, while the others were not agglutinated. The frequency of the former was 94% and the latter was 6%. This difference of agglutination of D. lablab extracts by washed RBC and whole blood may be due to some inhibited substances which is contained in human sera. Therefore, agglutination of D. lablab extracts by human sera was contained out. Normal human sera were also classified into two groups of DLI(Dolichos lablab inhibitor) by which agglutination of D. lablab with human RBC was inhibited and DLN(Dolichos lablab non-inhibitor) by which agglutination of D. lablab with human RBC was not inhibited. The frequency of DLI was 86% and DLN was 14% in 79 of normal human sera. There was no relation between the frequency of agglutination of human whole blood by D. lablab extracts and with various diseases, neither with ABO blood groups.