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      • 各種 胃手術後 Cortisone 이 胃液分泌에 미치는 影響에 關한 實驗的 硏究

        全奎榮,睦敦相 우석대학교 의과대학 1969 우석의대잡지 Vol.6 No.1

        Fourty dogs were used in this investigation, each ten of which were treated with gastrostomy, vagotomy, antrectomy and antrectomy with vagotomy. Two months postoperatively, free and total acidities and pepsin values of the gastric secretion were studied after administration of cortisone acetate, 0.5㎎. per Kg. of boly weight. Each sample was taken every 30 minutes 8 times following 12 hour fasting. Acidity was examined through To¨pfer Michaelis method and pepsin through Anson's-hemoglobin method. The results obained were as follows: 1. In the vagotomy group, 84.9% reduction in free acidity, 62.0% reduction in total acidity and 64.4% reduction in pepsin value comparing with the values of cortisone stimulated control (gastrostomy) group. Whereas, in this vagotomy group, cortisone injection produced 16.9% increase in free acidity and 74.3% increase in total acidity but 0.4% decrease in pepsin values comparing with the value of preinjection resting state. 2. In the antrectomy group, 85.5% reduction in free acidity, 67.4% reduction in total acidity and 87.4% reduction in pepsin value comparing with the values of control group. Whereas, in this antrectomy group, cortisone infection produced 15.5% increase in total acidity and 1.2% increase in pepsin value but 7.4% decrease in free acidity comparing with the values of preinjection resting state. 3. In the antrectomy with vagotomy group, 98.5% reduction in free acidity, 83.1% reduction in total acidity and 85.9% reduction in pepsin value comparing with the values of cortisone stimulated control (gastrostomy) group. Whereas, in this antrectomy with vagotomy group, cortisone injection produced 83.3% decrease in free acidity, 42.1% decrease in total acidity and 46.9% decrease in pepsin value comparing with the values of preinjection resting state.

      • KCI등재

        手術과 感染

        全奎榮 大韓法醫學會 1985 대한법의학회지 Vol.9 No.1-2

        Postoperative wound infection is one of the most common complication surgical practice primarily depends upon the healing of wounds without serious complications, and infections occurring in postoperative wounds can have significant effects on the patient's morbidity, prolongation of convalescence, unpleasant dressings, ugly scars and cost of medical services. The severity of nosocomial infection has increased with following problems, e.g., complexity of hospital, antibiotic abuse, use of immunosuppressive agent, malnutrition, increment of chronic disease, use of invasive devices and multiplicity of operations. Efforts to decrease the incidence of wound infection postoperatively have included modification of the operating room procedure, methods of preparation of the surgical field, skillful operation, prophylactic systemic antibiotics and delayed closure of contaminated wound.

      • 各種 開腹患者의 腹腔內裝液에 대한 細菌學的 檢索

        全奎榮 漢陽大學校 1977 論文集 Vol.11 No.-

        Acute panperitonitis is one of many critical surgical disease, and there are many problems in its treatment, though the an ibiotics therapy and fluid and electroyte therap, etc. are employed: The development of antobiotics made an epoch in the management of acute panperitonitis, and so surgical infections can be prevented without any difficulty. But the overuse of antibiotics and the appearance of antibiotic resistant strains have made new problems in surgical infection. To achieve the most effective management of acute panperitonitis, a culture of peritoneal fluid on exploratory laparotomy and an antibiotic sensitivity test to microorganisms are needed. In this paper, 188 cases of abdominal surgery (107 cases of non-peritonitis and 81 cases of acute panperitonitis) were examined using bacterial cultures of peritoneal fluid with 5% sheep blood agar in each case to study the kinds of bacteria, the detection rate of bacteria,the relation between the time from hollow viscus rupture to operation, would infection and mortality rate, and the antobiotics sensitivity test to microorganisms. The results obtained are as follows: 1. In 107 cases of non-peritonits, 97 cases (90.7%) were negative, and 10 cases (9.3%), positive. A total of 14 strains were found in 10 positive cases, E.coli being in 8 strains (51.7%), which was the largest in number. 2. 45 caese (55.6%) were positive, and 36 cases (44.4%), negative, in 81 cases of acute panperitonitis. Teh detection rate of bacteria in the following diseases was 12 cases (85.7%) out of 14 cases of typhoid perforation, 8 cases (80.0%) out of 10 cases of traumatic intestinal perforation, 11 cases (40.7%) out of 27 cases of perforated appendictis and 8 cases (38.1%) out of 21 cases of peptic ulcer perforation. 3. In 81 cases of acute panperitonitis, a total of 61 strains were found these consisted of 40 strains (65.6%) of E. coli, 5 strains (4.9%) of pseudomonas aeruginosa, etc. 4. 4 strains (36.7%) of β-hemolytic streptococcus, 3 strains (20.0%) of staphylococcus aureus were found in a total of 13 strains of peptic ulcer perforation, and it was noticed that the detection rate (46.7%) of Gram positive group in this disease was higher than the rate of other kinds of acute panperitonitis. 5. In acute panperitonitis due to hollow viscuc rupture, the relation between the time of perforation and that of operation showed a tendency of increasing the detection rate of bacill in the peritoneal fluis and the wound infection rate over 60 percent in about 24 hours. The mortality sfter operation was 3 cases (3.7%) whole operations were performed after 72 hours. Out of the three, two died of typhoid perforation and the cause of death was septicemia. 6. In sensivity test to the microorganisms, staphylococus auresus and β-hemolytic streptococcus were most sensitive to penicillin and geopen, and E. coli was most sensitive to gentamycin, geopen and kanamycin, and pseudomonas aeruginosa, to geopen and gentamycin.

      • 正常韓國人의 血淸 및 尿中 Na, K, Cl 濃度 및 1日 尿量에 對하여

        全奎榮 고려대학교 의과대학 1964 고려대 의대 잡지 Vol.1 No.3

        Sodium, potassium and chloride were measured in serum and urine; the former two by means of EEL Flame Photometer and the latter by Schales and Schales method. Serum samples were talien from 107 healthy Korean males and 104 females, while urine samples from 85 males and 93 females. Results obtained are as follows; 1) Serum Na total average: 141.34±13.77 mEq/L. male: 142.25±3.53 mEq/L. female: 140.40±k3.63 mEq/L. 2) Serum K total average: 4.47±0.51 mEq/L. male: 4.62±0.39 mEq/L. female: 4.32h0.41 mEq/L. 3) Serum C1 total average: 104.40±2.56 mEq/L. male: 103.91±2.59 mEq/L. female: 104.96±2.35 mEq/L. 4) Urine amount total average: 1729.83±623.91 cc/day. male: 1842.58±582.86 cc/day. female: 1626.77±579.30 cc/day. 5) Urine Na ⓐ average concentration: 190.35±44.90 mEq/L. male: 193.91±46.10 mEq/L. female: 187.09±43.45 mEq/L. ⓑaverage of daily output: 321.81±98.01 mEq/day. male: 347.43±94.23 mEq/day. female: 298.39±110.62 mEq/day. 6) Urine K ⓐ average concentration: 21.75±6.31 mEq/L. male: 21.41±6.10 mEq/L. female: 22.13±6.34 mEq/L. ⓑ average of daily ontput: 36.55±13.62 mEq/day male: 37.82±10.77 mEq/day. female: 35.39±15.74 mEq/day. 7) Urine C1 ⓐ average concentration: 187.93±45.19 mEq/L. male: 189.58±44.74 mEq/L. female;186.41±45.38 mEq/L. ⓑ average of daily output: 318.28±100.53 mEq/day. male: 339.26±91.59 mEq/day. female: 299.10±149.09 mEq/day. As far as serum. values of sodium, potassium and chloride are concerned, the author's results are similar to those of other reporters. individual variations of urinary concentrations and of daily output of these electrolytes are greater than those of serum. A comparison of these data with corresponding figures obtained from other reporters suggest that, in Korean, the concentrations and excretory amounts of sodium and chloride are significantly higher, while those of potassium are significantly lower than those of other reporters. It is speculated that this peculiarity of the urinary composition in Koreans is attributed to their low protein and high salt diet ingestion.

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