노인간호 교육이 간호대학생의 노인에 대한 지식과 노인간호 태도에 미치는 효과

홍성실(Hong, Sung Sil),조은주(Jo, Eun Joo),박정숙(Park, Jung Suk) 고신대학교 전인간호과학연구소 2015 전인간호과학학술지 Vol.7 No.-

Purpose: The purpose of this study was to examine the effects of gerontological nursing education on knowledge and attitude for the aged. The participants were 37 in third-year nursing students at K university in Busan, Korea. Method: The data was collected from Aug. 27th toward Nov. 26th, 2012. Result: As a result, the knowledge of nursing university students has been improved after the gerontological nursing education , the knowledge score of physical, physiological and social realm. There has been no significant change by the gerontological nursing education in the attitude of nursing university students for the Aged. Conclusion: Through this the gerontological nursing education in the future may be thought to change the knowledge and attitude of nursing university students affirmatively if the education program grafting the theoretical education together with the practice education is applied by apprehending the level of understanding and demand for the gerontological nursing of students

백혈병 생존 청소년의 신체적ㆍ정서적 후유장애, 사회적응 및 삶의 질

홍성실(Hong, Sung Sil),박호란(Park, Ho Ran),김광성(Kim, Kwang Sung),최선희(Choi, Sun Hee) 한국간호과학회 2014 Journal of Korean Academy of Nursing Vol.44 No.1

Purpose: This study was conducted to examine the late effects, social adjustment, and quality of life in adolescents who had been completely treated for childhood leukemia and their parents. Methods: Participants consisted of 41 pairs of adolescent survivors (13-18 years) and their parents. Parents checked for their child"s physical late effects. The Korean Version of Post-Traumatic Symptoms for psychological late effects, social functioning questionnaire for social adjustment and the PedsQL 4.0 Generic Core Scales for quality of life were completed by adolescents and parents. Data were analyzed using SPSS. Results: Twenty out of 41 adolescents had one or more physical late effects. Adolescents showed more serious psychological late effect than parents. Five children and seven parents had above cut-off scores and they were considered the high risk group for posttraumatic symptoms. Parent-reported scores were significantly higher than child-reported scores in terms of social adjustment and emotional functioning of quality of life. Low school functioning in adolescents was associated with physical late effects. Conclusion: The results indicate that long-term and systematic management for childhood leukemia survivors affect positive social adjustment and can further improve quality of life.

담배 흡연이 생쥐의 흉선 및 비장의 면역 기능에 미치는 영향

홍성실(Sung-Sil Hong),박윤아(Yun-A Park),이진우(Jin-Woo Lee),김미자(Mi-Ja Kim),남궁승(Seung Namkoong),구현정(Hyun-Jung Koo),손은화(Eun-Hwa Sohn) 한국산학기술학회 2021 한국산학기술학회논문지 Vol.22 No.9

본 연구에서는 담배필터를 통해 호흡기로 노출되는 주류연 흡연 장치를 구현하여 직접 흡연에 의한 주류연의 노출이 면역시스템에 미치는 영향을 생쥐모델을 이용하여 규명하고자 하였다. 실험동물(n = 15)은 대조군(sham군)과 담배 2개비/일 노출군 및 4개비/일 노출군으로 각각 나누고, 7일 동안 주류연을 노출시킨 후 체중변화와 면역기관 지수를 측정하였다. 주류연 노출이 면역세포의 기능에 미치는 영향을 확인하기 위해, lipopolysaccharide(LPS) 또는 concanavalinA(ConA) 자극에 대한 비장세포와 흉선세포의 증식력과 nitric oxide(NO) 분비량을 측정하였다. 실험결과, 4개비/일 고용량 노출군의 흉선, 비장, 간 무게가 대조군에 비해 각각 0.3, 0.2 및 0.2배 유의적으로 감소하였고(P<0.05), 흉선세포 생존율과 B세포 및 T세포 증식력이 감소하였다. 또한, LPS에 의한 비장세포의 NO 분비능도 감소하였다. 본 연구는 주류연 노출이 흉선과 비장에 직접적인 손상을 주며, 자극원에 대한 면역세포의 증식력과 NO 분비 등 방어능력을 유의적으로 약화시킨다는 것을 보여주었다. 이는 흡연과 관련된 면역질환 발생이 주류연의 노출에 대한 직접적인 면역기관의 손상과 자극에 대한 방어 기능의 약화가 관련되어 있음을 제시한다. This study investigated the effect of exposure to mainstream smoke (MS) through cigarette filters on the immune system in mice. Fifteen mice were divided into 3 groups; control (sham), 2 cigarettes smoked/day (CS), 4 CS. Changes in body weight and organ index were measured after exposure to MS for 7 days. The effects of exposure to MS on nitric oxide (NO) production and cell proliferation induced by lipopolysaccharide (LPS) or concanavalin A (ConA) in murine lymphocytes were also determined. Exposure to 4 CS reduced the organ indices of the thymus, spleen, and liver by 0.3-, 0.2-, and 0.2-fold (P<0.05), respectively. Exposure to MS also inhibited the lymphocyte proliferation by LPS or ConA and the NO production by LPS. This study confirmed that the immune organs were directly damaged as well as weakened in their cell function by exposure to MS. It provides direct evidence that the occurrence of various immune diseases caused by smoking is closely related to the impairment of immune functions by exposure to MS.

백혈병 청소년의 회복력 영향 요인

홍성실(Hong, Sung Sil),박호란(Park, Ho Ran) 한국간호과학회 2015 Journal of Korean Academy of Nursing Vol.45 No.4

Purpose: The purpose of this study was to identify the factors relating to resilience for adolescents with leukemia and examine the relationship between these factors. Methods: From June to September in 2014, 199 adolescents aged 11 to 21 participated in the study as they visited the out-patient clinic at C university hospital for follow-up care. To verify the predictors and the effects of resilience, uncertainty, symptom distress, perceived social support, spiritual perspective, defensive coping, courageous coping, hope, and self-transcendence were measured. Collected data were analyzed using hierarchical regression analysis with the SAS statistics program. Results: The final regression model showed that courageous coping, hope, and self-transcendence were significant predictors related to resilience in adolescents with leukemia and explained for 63% of the variance in resilience. Conclusion: The findings indicate that adolescent-oriented intervention programs enhancing courageous coping, hope, and self-transcendence should be provide for adolescents with leukemia in order to overcome illness-related stress and support physical, psychological and social adjustment.

간호학생의 영성과 임상실습 스트레스

홍성실(Sung-Sil Hong),홍정아(Jung-Ah Hong),전원희(Won-Hee Jun) 한국콘텐츠학회 2013 한국콘텐츠학회논문지 Vol.13 No.6

본 연구는 간호학생의 영성과 임상실습 스트레스 정도를 평가하고 이들 간의 관계를 파악하여 간호학생들의 영성증진과 임상실습 스트레스 중재방안으로 영성의 활용가능성을 확인하고자 시도하였다. 2개 대학의 간호학생 203명을 편의 추출하여 자가 보고식 설문지를 사용하여 자료를 수집하였다. 연구결과, 본 연구 대상자들의 영성은 5점 만점에 3.18점, 임상실습스트레스는 5점 만점에 3.42점으로 중간이상의 수준이었다. 하위영역별로는 영성의 경우 ‘삶의 의미와 목적’이 가장 높았고, 임상실습 스트레스에서는 ‘실습교육환경’에 대한 스트레스가 가장 높게 나타났다. 일반적 특성에 따른 차이에서는 영성은 종교와 전공만족도에 따라, 임상실습 스트레스는 성별과 전공만족도에 따라 유의한 차이를 보였다. 영성과 임상실습 스트레스는 유의한 부적상관관계가 있었다. 결론적으로, 간호학생들의 임상실습 스트레스를 감소시키기 위해서는 영성증진을 위한 교육프로그램 개발과 이를 효과적으로 교육과정에 접목시킬 수 있는 방안을 구축할 필요가 있다. The purpose of this study was to investigate the level of spirituality and stress of clinical practice and to identify the relationship of variables among nursing students. Data were collected from 203 nursing students using self-report questionnaire composed of demographic characteristics and two scales including spirituality and stress of clinical practice. Data were analyzed by frequencies, t-test, ANOVA, Pearson‘s correlation coefficients using the SPSS program. The mean score for spirituality and stress of clinical practice were above medium level, with the value of 3.18 and 3.42 out of 5 respectively. There were significant mean differences in spirituality according to religion and satisfaction on major while those in stress of clinical practice according to sex and satisfaction on major. Significant negative correlation between spirituality and stress of clinical practice was found. In conclusion, to reduce clinical stress in nursing students, it is necessary to develop and apply educational program for spiritual improvement.

Poloxamer-407로 유도한 이상지질혈증 생쥐에서 홍삼의 예방 효과

홍성실(Sung-Sil Hong),이진우(Jin-Woo Lee),박윤아(Yun-A Park),김성혁(Sung-Hyeok Kim),장소희(So-Hee Jang),하창우(Chang-Woo Ha),김미자(Mi-Ja Kim),남궁승(Seung Namkoong),구현정(Hyun-Jung Koo),손은화(Eun-Hwa Sohn) 한국산학기술학회 2021 한국산학기술학회논문지 Vol.22 No.10

본 연구에서는 홍삼의 이상지질혈증 개선 효능과 안전성을 조사하고자 하였다. Poloxamer-407(P407)에 의한 이상지질혈증을 유발한 동물모델에 홍삼추출물과 지질강하제 simvastatin을 2주간 복강 투여한 후 지질프로파일과 간독성의 조절효과를 확인하였다. 실험동물은 8주령 수컷 ICR 마우스(n = 30)를 6개 그룹(무처치군, P407 유도군과 홍삼추출물 10, 50, 100 mg/kg 투여군 및 simvastatin 투여군)으로 나누어 각 그룹 당 5마리씩 무작위로 배치하였다. 실험종료 후 각 그룹의 마우스에서 간, 부고환 지방, 흉선 및 비장을 적출 하여 중량을 측정하였다. 또한 혈액에서 총콜레스테롤, 중성지방, 저밀도지단백질, 고밀도지단백질을 포함한 지질프로파일의 변화와 glutamate oxaloacetate transaminase(GOT) 및 glutamate pyruvate transaminase(GPT)를 측정하였다. 실험결과 홍삼추출물 10 mg/kg 투여군에서 P407로 증가된 혈중 총콜레스테롤, 중성지방, 저밀도지단백질을 모두 유의적으로 감소시켰으며(p <0.05), 그 효과는 simvastatin 10 mg/kg 투여군과 유사한 수준으로 나타났다. 또한, 홍삼추출물은 혈중 GPT와 GOT 수치에 영향을 미치지 않았으며 주요면역기관인 흉선의 무게를 증가시켰다. 이러한 결과는 홍삼이 이상지질혈증에 예방 효과가 있고 지질관련질환에 대한 statin계열 약물의 보조물질로서 활용 가능성을 제시한다. This study aimed at investigating the efficacy and safety of red ginseng (RG) for improving dyslipidemia. After 2 weeks of intraperitoneal administration of RG and simvastatin (lipid-lowering medication) to an animal model with dyslipidemia induced by poloxamer-407 (P407), the regulatory effects on the lipid profile and hepatotoxicity were confirmed. 8-week-old male ICR mice (n = 30) were divided into 6 groups (control, P407-induced dyslipidemia group, RG 10, 50, 100 mg/kg group, simvastatin group). 5 mice were randomly placed in each group. At the end of the experiment, the weight of the liver, epididymal fat, thymus, and spleen was measured in each group. We also identified changes in the lipid profile, including total cholesterol (TC), triglycerides (TG), low-density lipoproteins (LDL), high-density lipoproteins (HDL), and determined the levels of the glutamate oxaloacetate transaminase (GOT) and glutamate pyruvate transaminase (GPT) in the blood. The results show that 10 mg/kg RG significantly reduced the increase of P407-induced levels of TC, TG, and LDL (p <0.05), similar to the simvastatin group. Moreover, RG did not affect the levels of GPT and GOT, and increased the weight of the thymus, a major immune organ. These results suggested that RG may be able to prevent dyslipidemia and has therapeutic potential as an adjuvant to statins for the management of lipid disorders.

잇꽃 에탄올 및 열수 추출물의 항노화 기반 항주름효과 비교

하창우(Chang Woo Ha),김성혁(Sung Hyeok Kim),장소희(So Hee Jang),홍성실(Sung Sil Hong),남궁승(Seung Namkoong),최혜숙(Hye Sook Choi),김윤규(Youn Kyu Kim),임정대(Jung Dae Lim),손은화(Eun Hwa Sohn) 한국약용작물학회 2022 한국약용작물학회지 Vol.30 No.3

간호대학생의 문제해결능력과 사회불안

차경숙(Kyeong-Sook Cha),전원희(Won-Hee Jun),홍성실(Sung-Sil Hong) 한국콘텐츠학회 2014 한국콘텐츠학회논문지 Vol.14 No.7

본 연구는 간호대학생의 문제해결능력과 사회불안 정도 및 이들 간의 관계를 파악하고 사회불안에 영향을 미치는 요인을 규명하는 서술적 조사연구이다. 연구대상자는 A시와 Y시에 소재한 2개 대학의 간호대학생 227명이었다. 구조화된 자가 보고식 설문지를 이용하여 자료를 수집하였으며, 자료 분석은 SPSS WIN 프로그램을 사용하여 빈도와 백분율, 평균과 표준편차, t-test, ANOVA, Pearson correlation coefficient, multiple stepwise regression analysis를 실시하였다. 연구결과, 사회불안과 문제해결능력 수준은 중간정도의 수준이었으며, 문제해결능력과 사회불안은 부적 상관관계를 보였다. 사회불안에 영향을 미치는 요인으로는 문제해결능력의 하위요인인 인지적 반응과 일반적 특성 중 지각된 대인관계가 유의한 것으로 나타났으며 이들 변수의 사회불안에 대한 설명력은 23.6%이었다. 결론적으로, 친숙하지 않은 사회적 상황에서의 인지적 왜곡을 탐색하고 이를 수정하는 교육과 상담 및 대인관계능력을 향상시키는 프로그램 적용은 간호대학생의 사회불안을 감소시키는데 효과적인 전략이 될 수 있다. This study was conducted to investigate the factors affecting the social anxiety in nursing students. A total of 227 nursing students participated in the study. Data were analyzed by frequencies, t-test, ANOVA, Pearson correlation coefficient, and multiple stepwise regression with SPSS WIN 18.0. The mean scores for problem solving ability and social anxiety were at the intermediate level. Problem solving ability negatively correlated with social anxiety. The significant predictors of social anxiety included cognitive reaction within the seven problem solving ability subscales and perceived interpersonal relationship. The regression model explained 22.6% of social anxiety. As a result, to decrease social anxiety in nursing students, nursing educators should develop educational intervention programs to change cognitive distortions presented in unfamiliar social situations and improve interpersonal relationships ability.

자운영 에탄올 추출물이 인간 진피 섬유아세포에 미치는 노화 방지 효과

장소희(So Hee Jang),하창우(Chang Woo Ha),김성혁(Sung Hyeok Kim),홍성실(Sung Sil Hong),박명례(Myung Rye Park),김윤규(Youn Kyu Kim),손은화(Eun Hwa Sohn) 한국약용작물학회 2022 한국약용작물학회지 Vol.30 No.5