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백금 히터가 내장된 평면형 Bi - Sb 다중접합 열전변환기의 특성
이현철,김진섭,함성호,이종현,이정희,박세일,권성원 ( H . C . Lee,J . S . Kim,S . H . Ham,J . H . Lee,J . H . Lee,S . I . Park,S . W . Kwon ) 한국센서학회 1998 센서학회지 Vol.7 No.3
A planar Bi-Sb multijunction thermal converter with high thermal sensitivity and small ac-do transfer error has been fabricated by preparing the bifilar thin film Pt-heater and the hot junctions of thin film Bi-Sb thermopile on the Si₃N₄/SiO₂/Si₃N₄-diaphragm, which functions as a thermal isolation layer, and the cold junctions on the dielectric membrane supported with the Si-substrate, which acts as a heat sink, and its ac-do transfer characteristics were investigated with the fast reversed de method. The respective thermal sensitivities of the converter with single bifilar heater were about 10.1 mV/mW and 19.8 mV/mW in the air and vacuum, and those of the converter with dual bifilar heater were about 5.1 mV/mW and 7.fi mV/mW, and about 5.3 mV/mW and 7.8 mV/mW in the air and vacuum for the inputs of inside and outside heaters, indicating that the thermal sensitivities in the vacuum, where there is rarely thermal loss caused by gas, are higher than those in the air. The ac-do voltage and current transfer difference ranges of the converter with single bifilar heater were about ±1.80 ppm and ±0.58 ppm, and those of the converter with dual bifilar heater were about ±0.63 ppm and ±0.25 ppm, and about ±0.53 ppm and ±0.27 ppm, respectively, for the inputs of inside and outside heaters, in the frequency range below 10 kHz and in the air.
Scopolamine Hydrobromide 및 $\ell$-Hyoscyamine의 생체이용성에 미치는 위산도의 영향
김창영,함성호,한상수,손동환,고건일,김재백,Kim, C. Y.,Ham, S. H.,Han, S. S.,Sohn, D. H.,Ko, G. I.,Kim, J. B. 한국임상약학회 1993 한국임상약학회지 Vol.3 No.2
The effects of gastric acidity on the bioavailability of scopolamine hydrobromide and ${\ell}$-hyoscya-mine were studied in rabbits. Each drug was administered orally at dose of 0.2mg/kg to gastric acidity controlled rabbits. The plasma concentration of scopolamine and ${\ell}$-hyoscyamine were determined by selected ion monitoring in GC/MSCScopolamine; m/Z= 138, ${\ell}$-Hyoscyamine; m/z= 124). Rabbits with hypoacidity showed significantly higher Cp and AVC than rabbits with hyperacidity after oral administration of each drug. From the results of this experiment, it is desirable that dosage regimen of dose of scopolamine and hyoscyamine should be adjusted when the drugs should be administered with antacids in clinical practice.