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전신마취하 구강악안면외과 수술환자에서 마취 및 수술시간이 술후 회복에 미치는 영향
염광원(Kwang Won Yum),남일우(Il Woo Nam),심유진(Yu Jin Shim),표성운(Sung Woon Pyo),한원일(Won Il Han),김규식(Kyoo Sik Kim) 대한구강악안면외과학회 1992 대한구강악안면외과학회지 Vol.18 No.3
To evaluate the effect of the duration of general anesthesia and surgery on the postoperative recovery, the 66patients with oral-maxillofacial surgery were divided into 5 experimental groups. According to he duration of anesthesia and surgery, the patients who had the 2 hours, 2 to 3 hours, 3 to 4 hours, 4 to 5 hours duration of anesthesia and surgery and more than 5 hours duration of anesthesia and surgery were allocated as a patient of experimental group A, B, C, D or E. The recovery indexes such as patient s mobility, respiratory status, change of systolic blood pressure, status of consciousness and skin colour were used to measure the patient s recovery state immediately after arriving on postoperative recovery area, and to measure the time to score the 10 points (full recovery state) of the recovery indexes in the postoperative area. Also the total duration of the patient s staying at postoperative area was measured. The following results were obtained: 1. There were no significant difference in patients from experimental group A to D on the average scores of the recovery indexes immediately after arriving on the postoperative recovery area. 2. In patients of experimental group E, the scores of the recovery indexes were significantly lower than the patients of any other experimental group. 3. The average full recovery time of the patients in the experimental group A was significantly shorter than the patients of any other experimental group. 4. The average full recovery time in patients of the experimental group B was also significantly shorter than the patients of experimental group E. 5. There was no significant changes on the average total duration of the patient s staying at the postoperative area in the patients of the experimental group A and B, but these patients were significantly shorter than the patients of the experimental group C, D or E on the patient s average total duration of staying at the postoperative area.
3차원 세포 프린팅과 탈세포화 된 췌장 유래 세포외기질 바이오잉크를 이용한 3차원 췌장 전조직 구조체의 제작
김석원(Seok-Won Kim),장진아(Jinah Jang),한원일(Won-il Han),김송철(Song-Cheol Kim),조동우(Dong-Woo Cho) 대한기계학회 2015 대한기계학회 춘추학술대회 Vol.2015 No.11
Islet transplantation into the portal vein has been widely used for the treatment of type 1 diabetes. However, intra-hepatic transplantation has many disadvantages including lack of vasculature, low efficacy and gradual graft attrition. Bio-engineered pancreas potentially provide an alternative transplantation site such as subcutaneous or directly into pancreas for islets with improving blood supply and cell viability compared to conventional intra portal transplantation. In this study, we developed printable pancreas derived decelluarized extracellular matrix (pdECM) bioink which enhances islet functionality and long-term survival by mimicking pancreas microenvironment. pdECM bioink have been tested for INS1β-cell viability and proliferation. To fabricate the optimal pancreas tissue construct by 3D cell printing, we checked the proper cell concentration by encapsulating INS1β-cell into pdECM bioink in different concentration. Our result shows the biological utility of pdECM bioink as a suitable biomaterial to fabricate the 3D pancreas tissue construct and to enhance cell functionality.
하악 치은암의 예후에 관한 임상적 연구(방사선학적 골흡수상과 예후와의 관계)
김규식(Kyoo Sik Kim),한원일(Won Il Han) 대한구강악안면외과학회 1994 대한구강악안면외과학회지 Vol.20 No.2
For the purpose of correct diagnosis. Appropriate treatment planning and improvement of prediction in prognosis of squamous cell carcinomas arising at the mandibular gingiva, evaluation on the prognosis according to the radiographic bone resorption feature and extent of the gingival squamous cell carcinomas of the mandible was performed with 54cases of squamous cell carcinomas arising the mandibular gingiva among the 197 intraoral squamous cell carcinomas to have been diagnosed and followed-up in the Department of Oral and Maxillofacial Surgery, Seoul National university Hospital from the 1st of January, 1983 to the 31th of December, 1992. The results were as follows: 1. In the classification according to the feature 15 cases were erosive type and 30 cases were invasive type. According to the extent of bone resorption of mandible, cases extended to the inferior alveolar canal(D) was 27 cases(50.0%), cases above the inferior alveolar canal(C) was 10 cases, cases of no bone involvement(A) was 9 cases and cases limited to alveolar portion was 8 cases. 2. Overall 5-year survival rate of all patients was 19.4% and in the treated cases regardless of methods, 5-year survival rate was 24.5%. 3. In the cases of invasive type bone resorption, 5-year survival rate was 12.0%, in contrast with 30.8% of invasive type. 4. Comparison between the extent of bone resorption, in the cases of no bone resorption(A) 5-year survival rate was 26.0%, in the cases of bone resorption above the inferior alveolar canal(C) and 14.3% in the cases of the bone resorption extended beyond the canal(D).