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16Kbps와 40Kbps의 Dual Rate G.726 ADPCM 음성 codec구현
김재오,한경오,Kim Jae-Oh,Han Kyong-Ho 한국전기전자학회 1998 전기전자학회논문지 Vol.2 No.2
본 논문에서는 G.726 ADPCM 음성방식을 기존의 단일 압축을 대신 16Kbps 와 40Kbps의 두 가지 압축율을 사용한 가변 압축방식에 의한 음성 코딩 방식을 다루었다. 음성의 묵음 또는 소 신호 부분은 음질의 향상보다는 데이터 비트 수를 줄이기 위한 저 전송 16Kbps 압축율을 적용하였고 임계값 이상의 대 신호 부분은 음질을 향상하기 위하여 40Kbps의 압축율을 적용하여 모든 신호를 단일 압축율로 코팅하는 방식에 비하여 전체적으로 압축율을 높여 전송 비트 수를 줄이면서 음질을 저하시키지 않도록 하였다. 분 논문에서는 시뮬레이션을 통하여 여러 가지의 임계값에 의한 가변 압축 코딩 방식에 대하여 압축율과 음질의 관계 를 다루었다. 또한 고정된 임계값에 대하여 입력 음성의 크기를 여러 가지로 변동하여 주변 배경잡음과 포화에 의한 음질의 저하를 고찰하여 가변 율에 의한 음성의 코딩방식에서 임계값과 입력의 크기가 음질 및 압축율에 미치는 영향을 다루었다. 각 시뮬레이션의 경우에 대하여 실지 음성의 원음에 대한 음질의 충실 도를 임의의 집단에 대하여 비교하여 음질의 충실 도를 확인하였다. 추후의 연구를 통하여 DSP에 의한 실시간 처리 시스템의 구현을 하고자 한다. In this paper, the implementation of dual rate ADPCM using G.726 16Kbps and 40Kbps speech codec algorithm is handled. For small signals, the low rate 16Kbps coding algorithm shows almost the same SNR as the high rate 40Kbps coding algorithm , while the high rate 40Kbps coding algorithm shows the higher SNR than the low rate 16Kbps coding algorithm fur large signal. To obtain the good trade-off between the data rate and synthesized speech quality, we applied low rate 16Kbps for the small signal and high rate 40Kbps for the large signal. Various threshold values determining the rate are applied for good trade-off between data rate and speech quality. The simulation result shows the good speech quality at a low rate comparing with 16Kbps & 40Kbps.
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이관복,박승춘,한경오,윤호인 충남대학교 수의과대학 동물의과학연구소 1994 動物醫科學硏究誌 Vol.1 No.-
It is important to study the activity of drug biotransformation enzymes, because from a pharmacological and therapeutic point of view these enzymes are resposible for eliminating most drugs. Their level is ciritical when deciding the dose regimen. (From a toxicological perspective, the role of these enzymes varies, with some of them being directly responsible for activation of certain chemicals to reactive intermediates with deleterious consequence to the animal.) Experiments were designed to measure in vitro, the activity of drug metabolizing enzymes in liver of Korean native cattle. The microsomal monooxygenase activities were evaluated utilizing specific substrates. The activities of BPDM and TST 6β-hydroxylase were seemed to be high level relatively to other monooxygenzses such as ECOD, EROD and AH. Interestingly, TST 16α-hydroxylase which is a maker enzyme for CYP ⅠLA was not detected in Korean native cattle. These results sugest that Korean native cattle have high contents of CYP IIB1 and CYP IIIA.
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인삼(人蔘) 추출액(抽出液)이 SO<sub>2</sub> Gas에 폭로(暴露)된 새앙쥐 호흡기상피(呼吸器上皮)의 섬모(纖毛)변화에 미치는 영향(影響)에 관한 연구(硏究)
김무강,조성환,류시윤,이근좌,한경오,이철호,Kim, Moo-Kang,Cho, Sung-Whan,Ryu, Si-Yun,Lee, Geun-Jwa,Han, Kyong-O,Lee, Chul-Ho 대한수의학회 1991 大韓獸醫學會誌 Vol.31 No.3
In order to investigate the effect of Panax ginseng extract and it's degree in mucociliary change of mice nasal septum epithelia exposured to sulfur dioxide, 96 ICR male mice were used. They were at first divided the 4th week, the 8th week or the 16th week groups according to the age after birth and 6 hour or 12 hour groups according to the $SO_2$ gas exposured hour in a day, and at control, 50mg, 100mg and 200mg injection groups according to the dosage of the freeze-drying powder of the ginseng extract which was injected into the mouse peritoneal cavities in the condition of the solution solved with physiological saline solution. Each subgroups which were divided finaly included 4 male mice. The histological tissue sections for observation were made from nasal septum, posterior nasal orfice and trachea. The results obtained by experiments were summarized as followings. 1. The loss of the nasal mucosa epithelial cilia of the mouse exponsure to the $SO_2$ gas after ginseng extract injection was apparently diminish eompare to those exposured only $SO_2$ gas without pretreatment of ginseng extract (p<0.01). 2. The inhibition effect for the loss of nasal mucocilia according to the ginseng extract dosages not found in this research (p>0.05). 3. There were differences in the loss of nasal mucosa cilia according to the $SO_2$ gas exposure time between the control group and ginseng extract pretreatment group (p<0.01). 4. According to the increase of the postnatal time, there were remarkable differences between the control group and the ginseng extract pretreatment groups in the loss of nasal mucosa cilia (p<0.01). 5. Ciliary changes of the posterior nasal orifice and trachea according to the $SO_2$ gas exposure time, mice age and ginseng dosages, were not dearly observed in this light microscopical observation.
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신규 퀴놀론 항균제 DW-116 의 in vitro 및 in vovp 항균활성
이진(Jin Lee),정용호(Yong Ho Chung),윤성준(Sung June Yoon),이덕근(Dug Keun Lee),황연하(Yun Ha Hwang),한경오(Kyung Oh Han),양희복(Hee Bog Yang) 한국응용약물학회 1997 Biomolecules & Therapeutics(구 응용약물학회지) Vol.5 No.2
The in vitro and in vivo antibacterial activity of DW-116, a newly synthesized fluoroquinolone, were compared with those of other quinolones. DW-116 exhibited more potent antibacterial activity than rufloxacin and lower activity than ofloxacin and ciprofloxacin in in vitro assay. But, DW-116 particularly showed strong activity against the family of staphylococci including methicillin-sensitive staphylococcus and its activity was more active than that of ciprofloxacin. The time-kill curve studies showed rapid bactericidal activity for DW-116. The post-antibiotic effect of DW-116 was observed between 0.66 and 5 hours. The therapeutic efficacy of DW-116 against respiratory infection with P. aeruginosa was as strong as that of ciprofloxacin and its effect against urinary tract infection with E. coli was more effective than rufloxacin. The excellent therapeutic efficacy of DW-116 against these local infections is due to its good pharmacokinetic profiles.
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