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      • KCI등재

        댕댕이나무(Lonicera coerulea var. edulis) 열매의 항염증 효과 연구

        김정화(Jeong Hwa Kim),조미나(Mi-na Jo),한주환(Ju Hwan Han),표승현(Seung Hyeon Pyo),김태수(Tae Soo Kim),김은희(Eun Hee Kim),이재권(Jae Kwon Lee) 대한약학회 2016 약학회지 Vol.60 No.5

        In this study, we demonstrated the anti-inflammatory activities of two kinds of blue honeysuckle (Lonicera caerulea var. edulis Turcz, Lonicera caerulea var. longibracteata f. ovata Hara) extracts in the LPS-stimulated macrophages. These two extracts showed non-cytotoxic activity, even at the high concentration. These two extracts of honeysuckle reduced the production of nitric oxide, cyclooxigenase-2 and pro-inflammatory cytokines. The inhibitory activities of two extracts of honeysuckle were found to be caused by blockage of NF-κB activation.

      • KCI등재

        뇌졸중 환자들을 위한 한국어판 Modified Rivermead Mobility Index의 측정자간 신뢰도와 동시 타당도

        안승헌 ( An Seung-heon ),이규창 ( Lee Gyu-chang ),이경봉 ( Lee Kyeong-bong ),이동건 ( Lee Dong-geon ),송선해 ( Song Sun-hae ),표승현 ( Pyo Seung-hyeon ) 대구대학교 특수교육재활과학연구소 2016 특수교육재활과학연구 Vol.55 No.4

        본 연구의 목적은 뇌졸중 환자의 Modified Rivermead Mobility Index(MRMI)의 측정자간신뢰도와 동시 타당도를 알아보는 것이다. 본 연구에서는 뇌졸중 환자 42명을 대상으로 하였다. MRMI의 측정자간 신뢰도(Inter-rater reliability)를 알아보기 위해 대상자들은 MRMI를 이용한 검사에 2회 참여하였다. 또한, MRMI의 동시 타당도를 알아보기 위하여 수정된 기능적 보행 지수(Modified Functional Ambulation Category, MFAC), 수정된 5m 보행 속도 검사, 일어나 걸어가기 검사(Timed Up & Go test, TUG), 버그 균형 척도(Berg Balance Scale, BBS), 수정된 바델 지수(Modified Barthel Index, MBI), 그리고 퓨글 마이어 평가(Fugl Meyer Assessment, FMA)에 참여하였다. MRMI의 측정자간 일치율은 급간내 상관계수(Intraclass correlation coefficient; ICC), 내적일치도(Cronbach`s α), 가중치 카파 계수(Weighted Kappa coefficient)를 이용하였고, MRMI의 개별 항목과 총점 간의 관계는 스피어만 상관 계수(Spearman Correlation Coefficient)를 이용하였다. 또한 MRMI의 표준오차 측정(Standard Error Measurement, SEM)과 최소 감지 변화(Minimal Detectable Change, MDC)를 구하였다. MRMI의 동시 타당도는 MFAC, 수정된 5m 보행 속도 검사, TUG, BBS, MBI, FMA와의 관계를 알아보았다. 본 연구의 결과, MRMI의 측정자간 일치율은 가중치 카파계수 .64∼.84, MRMI 개별항목과 총점 간의 상관계수는 r=.89∼.96, MRMI의 Cronbach`s α 계수는 .97, 개별 항목을 삭제한 경우에도 평균 .96∼.97로 높은 수준으로 나타났다. 또한, MRMI 총점의 ICC는 .97(.94∼.98), SEM은 1.32점, MDC는 3.66점으로 매우 신뢰할 만 수준으로 나타났다. MRMI의 동시 타당도에서 MFAC(r=.64), 수정된 5m 보행 속도 검사(r=.73), TUG(r=-.76), BBS(r=.83),MBI(r=.83), FMA(r=.56∼.59) 등과 높은 상관관계가 있었다. 게다가, 대상자들의 이동성은 실제 3.6점 이상 변화될 수 있는 것으로 확인되었다. 본 연구를 통해 MRMI는 높은 측정자간신뢰도와 동시 타당도가 있는 것으로 확인되었고, 만성 뇌졸중 환자의 이동성을 평가하는데 있어 유용하게 사용될 수 있을 것으로 사료된다. The purpose of this study was to investigate the inter-rater reliability and concurrent validity of the Modified Rivermead Mobility Index(MRMI) for stroke survivors. 42 stroke patients were participated in the study. The MRMI was administered in 2 testing sessions. Inter-rater reliability (Intraclass Correlation Coefficient; ICC), Internal consistency, and Weighted Kappa coefficient were used to examine the level of agreement between raters. For scale the item-total correlation and alpha if each item was deleted were calculated. Also we used to the Absolute reliability indices, including the Bland and Altman method, the standard error of measurement(SEM), and the Minimal Detectable Change(MDC). The concurrent validity was examined by correlating results to Modified Functional Ambulation Category(MFAC), 5m Walking Test(5mWT), Timed Up & Go test(TUG), Berg Balance Scale(BBS), Modified Barthel Index(MBI), Fugl Meyer Assessment(FMA). The mRMI meets the following requirements; 1) Inter-rater exact agreement for separate items was between Weighted Kappa=.64-.84. 2) The item-to-total correlations were all significant, ranging from r=.89∼.96(p < .01). MRMI showed good internal consistency(Cronbach`s α=.97). Individual items also possessed high internal consistency .96∼.97. Inter-rater reliability was excellent for ICC2,1=.97(.94~.98) for mRMI summary score and excellent SEM and MDC were 1.32, 3.66 respectively. 3) The mRMI were demonstrated high concurrent validity with the FAC(r = .84), the 5m WT(r = .73), TUG(r = -.76), BBS(r = .83), MBI(r = .83), and FMA(r = .56 ~ .59 p < .01). In addition, there needs to be a difference of more than 3.6 points(MDC score) in the overall score to detect true change in the subjects level of mobility. The MRMI makes it feasible to measure changes in mobility in routine clinical practice with high inter-rater reliability and concurrent validity.

      • 無對象繪畵의 根據와 限界

        表丞鉉 誠信女子大學校 1976 硏究論文集 Vol.9 No.-

        Among the pros and cons for non-objective art, the analogy of the pure music is very important. But what is possible to the music is not always possible to the painting. There is a serious difference between spacial art and music-time-expression. One of the critics suggests that the thinness of non-objective painting is due to the relative shallowness of the space within which the painting is composed of. This may not be true. The shallowness is not of the space but of time. As the time is the essence of life, a tendency of retreat of humanty results in that sort of art. We can not underetand it without the knawlege of the back-round; the artist himself, his opinion, ism etc., separhtely from of art.

      • Pop Art의 時代的 必然性과 그 展開方法에 關하여

        表丞鉉 誠信女子大學校 1983 硏究論文集 Vol.17 No.-

        Most successive styles in the arts, frequantly react to the one that precedes them. In this way, the new style expresses the changing character of the times. Pop Art was in pact a reaction against the highly personal, often non-objective nature of Abstract Expressionism. Although Pop Art is generally thought of as an American phenomenon, it was actually born in England in the Mid-1950s. At first, British Pop Art growth in London at the Institute of Contemporary Art Called the Independent Group. Hamilton who was one of the best member of IG Group, is a disciple of Marcel Duchamp, and it should be noted that Duchamp'xs, philosophy of art or anti-art has been perhaps the major influence on pop artists. The important point about Hamilton's, and subsequent that their purpose is not satirical or in any way antagonistic. As in Britain, Pop Art in all its manifestations was given its greatest impetus in America during the 1960's. This was an art which had a natural appeal to American artists, living in the midst of the most blatant industrial and commercial environment. For the American Pop Artists, once they realized the tremendous possibilities of their every day environment in thecreation of new subject matter, the result was more bold, overpowering than in the case of their European counterparts. There were many indications that American painting would return to a new Kind of Figuration, a new humanism. There were a great many precedents: Some fifty years had passed since the seeds of Pop were sown by Cubist collage: in retrospect it is amazing that commercial subject matter had not been 'discovered' as the total basis for fine art long before this. The Surrealist objects and found objects of the 1930's, like Jean Dubuffet's work of the early 1950's, were selected for their resemblance to something else a dream, a figure, or a subconscionsimage: ediate comprehension would have detracted from them. Pop Art is instantly to the point, extroverted rather than introverted. Since mid-century there has been an increasing number of works by contemporary American artists that take as their subject other art. The "Art-About-Art" theme first appeared prominently in the 1950's and has gained importance since the 1960's with the advent of the Pop Art movement. The works paraphrase, reinterpret, or feature the art of both Old and Modern Masters, as well as early and recent. American art, and they often display impudent humor, satire, and parody.

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