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      • KCI등재후보

        Radiofrequency Ablation for Metastatic Hepatic Tumor in Colorectal Carcinoma

        최정혜,Myung-Ju Ahn,Hyunchul Rhim,Heung Woo Lee,Ho-Suk Oh,Young-Yeul Lee,Il-Young Choi,In-Soon Kim 대한암학회 2004 Cancer Research and Treatment Vol.36 No.2

        Purpose: The purpose of this study was to assess the efficacy and safety of radiofrequency ablation (RFA) to treat hepatic metastasis in patients with colorectal carcinoma. Materials and Methods: Between May 1999 and July 2002, a total of 45 tumors in 24 patients with colorectal cancer were treated with RFA. Thirteen patients received systemic chemotherapy after the RFA procedure. The ablation was performed percutaneously under ultrasound guidance using cool-tip or expandable electrodes and an RF generator. The medical records as well as the CT scan results taken every 3 months were retrospectively reviewed. Results: The median follow-up duration of the surviving patients was 11.7 months (4.6~32.2 months). Complete tumor necrosis was achieved in 17 patients (70.8%) on an immediate (〈24 hrs) CT scan. The median survival was 17.1 months. The 1- and 2-year survival rates were 80.5 and 25.8%, respectively. In a univariate analysis, complete necrosis, tumor size and post-RFA chemotherapy were significant factors for survival. Nineteen of the 24 patients developed a recurrence or progressed (79.2%). The median progression free survival was 5.5 months. There were no treatment related deaths or serious adverse effects, with the exception of one case of respiratory failure. Conclusion: These results suggest that RFA is a well-tolerated and effective method to treat hepatic metastasis in colorectal carcinomas.(Cancer Res Treat. 2004;36:128-131)

      • KCI등재
      • KCI등재후보

        당뇨 환자에서 활차 운동 후 혈중 t-PA 및 PAI-1 의 변화

        최정혜(Jung Hye Choi),김순길(Sun Gil Kim),이응수(Woong Soo Lee),김태화(Tae Wha Kim),김태영(Tae Young Kim),신진호(Jin Ho Shin),이재웅(Jae Ung Lee),김경수(Kyung Soo Kim),김정현(Jeong Hyun Kim),임헌길(Heon Kim Lim),이방헌(Bang Hun Lee) 대한내과학회 1999 대한내과학회지 Vol.56 No.5

        N/A Objectives : Plasma fibrinolytic activity is determined by the balance between plasmonogen activators and their inhibitors. The aim of this study was to compare the fibrinolytic activity before and after exercise of the type 2 diabetic patients with control group. Methods : We measured plasma tissue-plasminogen activator (t-PA) and plasminogen activator inhibitor-1 (PAI-1) antigen before and after standardized treadmill exercise in 21 type 2 diabetic patients (14 men, 11 women, ages 46.2±5.6 years) and 21 sex and age- matched control group (10 men, 11 women, ages 48.6±5.4 years). Results : 1) Post exercise t-PA antigen increased in both diabetic group (from 7.36±3.89 to 10.62±4.81 ng/ml, p<0.05) and control group (from 8.30±3.99 to 10.99±5.52 ng/ml, p<0.05). But the rise in t-PA antigen with exercise was similar in both group. 2) Both base line and post exercise PAI-1 antigen levels were similar between the diabetic group (from 29.46±10.35 to 31.48±12.94 ng/ml, p>0.05) and control group (from 30.04±10.40 ng/ml to 31.06±10.88 ng/ml, p>0.05). 3) In diabetic group, significant correlations between base line PAI-1 antigen levels and serum triglyceride levels were observed. And post exercise PAI-1 antigen levels were correlated with systolic blood pressure. Conclusion : The results show that plasma t-PA antigen level is increased after vigorous exercise in patients with type 2 diabetes mellitus and plasma PAI-1 antigen level is not changed. The increment of plasma t-PA level is not different with healthy subjects.

      • KCI등재

        한국과 미국 성인자녀의 노부모와의 관계의 질과 부양행동 비교연구

        최정혜(Choi, Jeong Hye) 한국노년학회 2009 한국노년학 Vol.29 No.2

        The purpose of this study is to compare in the U.S. and Korea regarding adult children's quality of relationship and care provision for their elderly parents. The study sample consist of 320 adult children in the U.S. and 554 adult children in Korea with at least one parent living. The U.S. study sample is drawn from the State of California, and the Korean sample is drawn from Gyeongsangnamdo Province. The study result shows that the U.S adult children score higher than the Korean adult children in the quality of relationship measure for their elderly parents. And Korean adult children score higher than the U.S. adult children in the care provision measure for their elderly parents. It is found that the most significant factor influencing American adult children's care provision is caregiving attitude for elderly parents, while for Korean adult children, it is the quality of the relationship between adult children and elderly parents. This study results can serve as a foundation for understanding the U.S. and Korean differences regarding adult children's support for their elderly parents and for providing a solution to caregiving issues for elderly parents. 본 연구는 한국성인자녀와 미국성인자녀의 노부모와의 관계의 질과 부양행동을 비교하였다. 이를 통하여 한국과 미국 두 나라의 성인자녀와 노부모와의 관계 및 부양에 대한 문화적인 차이를 살펴보고, 나아가 우리나라 노부모 부양의 발전 방안모색에 유용한 자료를 제공하고자 한다. 연구대상자는 만 60세 이상의 노부모가 적어도 1명이상 살아있는 성인자녀로서, 미국 캘리포니아 주의 성인자녀 320명과 한국 경상남도의 성인자녀 554명 이다. 연구결과, 성인자녀의 노부모와의 관계의 질은 미국 성인자녀가 한국 성인자녀보다 더 높게 나타났으며, 성인자녀의 노부모 부양행동은 한국 성인자녀가 미국 성인자녀보다 더 높게 나타났다. 성인자녀의 노부모부양행동에 가장 영향을 미치는 변인은 미국은 노부모부양의식으로 나타났으며, 한국은 노부모와의 관계의 질로 나타나 나라간 차이를 보였다. 본 연구 결과를 통하여 노부모 부양행동에 있어서 미국의 경우 성인자녀의 노부모부양의식의 중요성을 알 수 있었고, 우리나라의 경우 성인자녀와 노부모의 세대 간 관계의 질이 중요함을 알 수 있었으므로 향후 우리나라의 노부모 부양정책 방안과 관련하여 성인자녀- 노부모 관계의 질을 강화할 수 있는 프로그램 모색이 필요하다하겠다.

      • KCI등재

        노부모가 지각하는 성인자녀와의 결속도 및 갈등에 관한 연구

        최정혜(Jung Hye Choi),김태현(Tae Hyun Kim) 한국노년학회 1991 한국노년학 Vol.11 No.2

        This research is written in light of the fact that under the present circumstance research on solidarity between aged parents and adult children is almost non-existent. This research intends to compare the city and country. The purpose of this research is to investigate the variables of the elderly problem and to provide useful suggestions on the direction of the establishment of policy relating to the elderly problem. In this research, a questionaire was used composed of a solidarity between aged and adult children index, a discord index, a self-respect index, and a self-control index. The subjects of the inquiry were elderly males and females over the aged of sixty who had one or more married children, and who lived in the rural or urban areas of Kyung Sang South Province. Finally, there were 450 questionaires used in the analysis : 225 in the city, and 225 in the country. The gathered materials were implemented using the SAS Program. The results are as follows : 1) 70.9% of aged parents felt that solidarity was on the low side when asked if their perception of solidarity with their adult children was below average. Also, 67.6% of aged parents felt that discord was on the high side when asked if their perception of discord with their adult children was above average. In addition, aged parents' discord with their adult children was higher in the country than in the city. 2) it was found that aged parents' perception of the variables exerting influence on solidarity with their adult children depended on the age of parents, economic level, type of dependence, gender, region of domicile, and existence or non-existence of spouse. 3) it was found that aged parents' perception of the variables exerting influence on discord with their adult children depended on educational level of parents, health, economic level, type of family, type of dependence, gender, and region of domicile. 4) the intermediary variables of self-respect and self-control were both found to be noticeable factors in aged parents' perception of solidarity and discord with their adult children. 5) it was found that type of family was the factor exerting the greatest power of influence on aged parents' perception of solidarity with their adult children. This was found to be the same both in the city and in the country. 6) it was found that aged parents' perception of solidarity with their adult children had a positive effect on the alleviation of aged parents' discord. 7) the results of the path analysis on aged parents perception of solidarity and discord with their children showed that the indirect path of the intermediary variable of the power. We see from the above results that in order to increase solidarity between aged parents and their adult children and to alleviate discord between them, rather than having a unilateral govermental policy of aged parents' dependence, a policy must be promulgated for elderly dependents which takes into account the differences in the actual situations found in rural and urban areas. In addition, the intermediary variables of self-respect and power of self-control are considerde to be important factors exerting influence on the alleviation of aged parents' discord.

      • KCI등재
      • 『남명집』에 나타난 남명의 실천사상이 부모의 아동양육태도에 주는 함의

        최정혜 ( Jeong-hye Choi ) 경상대학교 중등교육연구소 2016 중등교육연구 Vol.28 No.-

        본 연구의 목적은 부모의 올바른 자녀양육태도 정립을 위하여 우리전통에서 그 해법을 찾아보고자 하였다. 이에 본 연구는 조선시대의 대학자이며 경남지역의 정신적 지주인 남명의 실천 사상을 재조명하여 부모양육태도와의 접목을 시도하였다. 본 연구를 통해 나타난 결과는 다음과 같다. 첫째, 남명의 경의사상을 통한 실천은 부모의 아동양육태도 적용에 있어, 부모가 아동에게 자신의 마음을 인식하고 잘 조절하여 자기 통제력이 발달되도록 양육할 수 있다. 나아가 아동의 인격적 성장을 도모하도록 영향을 줄 수 있다. 둘째, 남명의 일상생활을 통한 실천은 부모의 아동양육태도 적용에 있어, 하학상달의 원리를 적용할 수 있으며, 이는 아동기의 인지발달 단계와도 일맥상통했다. 또한 부모는 아동에게 일상생활에 필요한 기본예절교육, 타인배려의 공동체교육 등 기본교육 강화를 적용할 수 있다, 셋째, 남명의 마음 수양을 통한 실천은 부모의 아동양육태도 적용에 있어, 화, 항, 직, 방의 원리를 적용할 수 있다. 결론적으로 조선시대 남명의 실천 사상은 현대를 살아가는 부모들의 아동양육태도에 효과적으로 적용될 수 있다. The purpose of this study is to resolve the problems of child-battering happened by their parents through the reviewing of Nam-myeong`s literatures and educational viewpoint for taking care of our children. Nam-myeong is the most famous scholar in the Choseon dynasty and his educational pensee is highly noble and ideal for the education of our children. It will provide the righteous solution for the contemporary parents who have to take care of their children. The results obtained from this study are as follows: First, Kyong-eui ideology with established practice can lead for the children to develop their self-control ability and influence to do the good-natured behavior Second, daily-life practice of Nam-myeong can be applied to teach their children how to solve the problems starting from the easy question to difficult one, which is well agreed with their degree of cognitive development. Third, mind-control practice of Nam-myeong is applicable for our children to do the things in everyday life with harmony, responsibility, right attitude, sleek and clean. In conclusion, it can be expected that educational viewpoint of Nammyeong is effectively applicable to contemporary parents who have to take care of their children in our modern society.

      • KCI우수등재

        이용자 생산 콘텐츠 플랫폼 사이트 내에서 생산자 참여가 소비자 선택과 몰입에 미치는 차별적 영향

        최정혜(Jeong Hye Choi),손정민(Jung Min Son),박경민(Kyung Min Park),박선주(Sun Ju Park),정승화(Seung Wha Chung) 한국경영학회 2013 經營學硏究 Vol.42 No.2

        User-generated contents (hereafter, UGC) are the contents produced by individual users. In addition to the conventional role of individuals as consumers, nowadays individuals can play an additional role as producers. Individual producers create their own virtual contents and share them with others, and some active producers try to communicate with their UGC users. As information technology advances and diffuses over space and time, this UGC-related market has grown substantially with the growing numbers of participants and the high quality contents. The popular UGC platform sites include: Youtube.com, Twitter.com, Facebook.com, and Wikipedia.com, which in fact belong to the top 10 Internet sites according to site traffic(Alexa Internet Inc., 2012). There has been much effort to understand the mechanism by which online performance is determined. Well-studied measures include product sales(Van den Bulte and Joshi, 2007; Dellarocas et al., 2007), sales ranks(Chevalier and Mayzlin, 2006), company profit(Liu, 2006; Chan et al., 2011). Key factors to derive online performance include product quality(Dichter, 1966), word-of-mouth among consumers(Liu, 2006), producers` particiation(Schwartz et al., 2011). For example, it is well known that product popularity has a positive influence on product sales(Kohler et al., 2011). Here, product popularity serves as a proxy for product quality and performance is measured using consumers` choices. UGC platformsites provide users opportunities to not only select but also engage by reviewing products and making recommendations, and this kind of behavior can reflect consumers` engagement(O`Hern et al., 2011; Schmitt et al., 2011). Thus, this research extends performance measures beyond choice-based ones and incorporate consumers` engagement-based measure. On the UGC platform sites, producers can easily observe communication among users, and some producers participate in consumers` conversation(O`Hern et al., 2011). Despite this growing producers` participation, there is limited research on its effect on performance. On the one hand, producers` communication with users can improve the relationship with users, which in turn increases users` interest and promote product choice(Doney and Cannon, 1997). On the other hand, producers` participation can inhibit consumers from speaking out(Kohler et al., 2011). Therefore it is needed to understand whether producers` participation improves or deteriorates UGC performance. This research collects data from Youtube.com in the category of `how to & style` using snowball sampling. On Youtube.com, users can view videos and leave comments, and also upload video clips. All the video-related and users` activities are collected and analyzed. The empirical analyses support all the proposed hypotheses. First, producers` participation has the positive impact on the choice-based performance and this positive effect strengthens with increasing product popularity. This means that when producers of popular products communicate with consumers, the choice-based performance improves(Kohler et al., 2011). On the contrary, producers` participation has the negative impact on the engagement-based performance and this negative effect gets stronger as products become more popular. This means that when producers of popular products participate in consumers` conversation, consumers are demotivated and do not express their opinion(Dellarocas et al., 2010). Producers` particition has the positive effect on consumer choice but the negative effect on consumer engagement. Therefore, in order to understand to what extent producers participate, both performance measures must be considered simultaneously. Further empirical investigation provides the following practical guidelines to decide on the level of producers` participation. First, producers of popular UGC should activily communicate with users. Avid participation by producers of popular UGC increases consumers` choices to the much greate

      • KCI등재

        저장 땅콩에서 분리된 Aspergillus flavus의 다양성 및 독소생성능

        최정혜 ( Jung-hye Choi ),나주영 ( Ju-young Nah ),이미정 ( Mi-jeong Lee ),임수빈 ( Su-bin Lim ),이데레사 ( Theresa Lee ),김점순 ( Jeomsoon Kim ) 한국균학회 2021 韓國菌學會誌 Vol.49 No.3

        Peanuts in storage were estimated for mycotoxigenic fungi and mycotoxins. Peanut samples collected from storages in Gochang were mainly contaminated with Fusarium (17.2±28.0%), Penicillium (12.4±28.0%), and Aspergillus (8.0±7.6%). Other genera, including Talaromyces, Rhizopus, Rhizoctonia, Trichocladium, Clonostachys, Mucor, Chaetomium, Trametes, Epicoccum, and Humicola, were also found. Although aflatoxins were not detected in the peanut samples, 29 strains of Aspergillus flavus were identified using molecular marker genes. Among them, 17 selected isolates produced aflatoxins in solid culture media ranging from 0.61-187.82 μg/kg. All of them could produce both aflatoxin B<sub>1</sub> and B<sub>2</sub> and some (n=5) produced additional G<sub>1</sub>, G<sub>2</sub>, or both. This study is the first report that A. flavus stains obtained from Korean stored peanut are aflatoxigenic.

      • KCI등재

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