초파리集團의 選擇利益에 관한 遺傳學的 硏究

崔五木,朴殷圭 圓光大學校 基礎自然科學硏究所 1990 基礎科學硏究誌 Vol.9 No.1

A study on the genetic behavior of sexually selective advantage between wild and visible mutant groups of Drosophila melanogaster was carried out. From nine Korean localities, wild type fruit flies, Drosophila melanogaster, were collected from early September to late October in 1987. For the present experiment using population cages, each cage of nine localities in Korea and Ore-gon-R, ten cages in total, contained two groups of X-linked mutant fruit flies, m : miniature, y : yellow and wild type fruit flies sampled from different localities. Ten pairs of wild type, the miniature and the yellow respectively, were put into a cage, then thirty pairs per cage. Having examined whether sexually selective advantage played among the different phenotypes. There were observed gene arrangement and genotype frequencies in every generation through twenty five successive generations. In all cases the frequency of the wild type increased and that of the mutant types declined, though at different rates in different populations. In each population cage, the culture of Drosophila melanogaster were set up and contained the wild type flies collected from nine Korean localities and miniature and yellow mutant flies which have been feeding in the Laboratory room of Won-Kwang University. Although they were much alike in survival, the miniature female flies were not found at all from the culture after 1-15 generations. The miniature male flies were also eliminated in each population cage through eleven to sixteen generations. Through one to eight successive generations, the yellow female flies were eliminated and so did the yellow male flies through eleven to nineteen successive generations. In regard to this fact, the low efficiency of mutant flies in mating was suggested. All the females discriminated against the mutant males. It seemed reasonable to assume that such selective disadvantage was so effective to eliminate the "less fit" flies in a remarkably short span of time. Environmental variables such as latitude and longitude were hypothesized to cause and interrelation ships between surrounding conditions and sexually selective advantage on +gene -bearing chromosome. The coast-to-inland cline and north-to-south cline in the western side of the Korean peninsula have been disclosed in the present study. And summarized are that, as to the gene frequencies of wild, miniature, yellow, and yellow-miniature of Drosophila melanogaster, the strength of selective advantage was varied due to localities. The wild type was the strongest in selective advantage and weakened in order of yellow-miniature, yellow and miniature.

노자의 생명 치유사상

최오목 원광대학교 대학원 2008 論文集 Vol.40 No.-

The Tao is divided into everything by it's rule. The division of Tao is discribed as the following formations in the Lao-Tzu book. The value of Tao is absolute and boundless, and it is the real source of every kind of goodness. so that Lao-Tzu thaught us to return to the truth of Tao. Lau-Tzu denies the language, the reason, the sensation and the experience to coginze Tao. These instruments have been considered as most useful and appropriate instruments for cognizing truth. Therefore, how to cognize Tao without these instruments is the impotance of the thought of Lao-Tzu. Two important properties of the Tao of Lao-Tzu are formless and nameless. as the formless Ch'i which is fundamental matter for nature in Lao-Tzu's philosophy run through ten-thousand thing, it integrates subject and object, human and cosmos, one and all into one. With the development of material civilization, modern civilization has been the crisis it has destroyed the naturation of life. The thought of Lao-Tzu of nature deals with the issue of idleness leaving itself which can solve the life of naturational destruction in this situation. And, I think Lao-Tzu's view of nature is quite important as a new ethical idea for the naturation rather then any other thought. First, nature and human cannot be seperated and human is the part of nature. In order to solve the naturational problem and preserve the only existing earth. all areas such as science, politics, economic, etc. are important. the most important thing among them is to change the value which is the basis all of these. It is required to trans form from the view of mechanism and human centered idea to the value of union view with nature. therefore, human is not the manager of ecosystem but the part of nature under the universe which should realize and follow the nature's way. Second, the motional law of nature is not based on the movement in a straight line but based on the repetition and circulation. That is, the way of nature is incessantly operated and comes back when it reaches in certain point, then it starts again. So does the recovery of human. There is definitely a disaster which threats the existence of human being among the convenience of materials that we are now enjoying. Third, the nature moves by as itself. Idleness is not the inaction but adapts the behavior of oneself in the movement of Tao without manipulating it artificially. that is, it follows in the order of nature. Therefore, it is the nature itself remains intact. Lao Tzu's view of nature which has this kind of meaning can bring the conversion of idea about the natural life and this though makes people have a humble and modest attitude to the nature as it suppresses the human desire. Because Ten-thousand thing, that is, through the formless Ch'i, have sympathized and will sympathize. Thus we can cognize Homestasis though the Ch'i, Lao-Tzu suggest that we desire more less, we make our body-mind tender, and we make our heart tronquil, as the method of cognition through Ch'i.

磁氣場내 초파리 集團의 發生率 變動과 選擇不利에 관한 遺傳的 硏究

朴殷圭,朴泰永,崔五木 圓光大學校 1994 論文集 Vol.28 No.2

本 硏究에서는 韓國 仙遊島 自然集團 野生型 초파리와 可視 突然變異型 黃色體小翅 초파리를 Helmholtz coils를 이용하여 만든 여러 가지 다른 磁氣場內의 集團에서 發生率 變動과 性的 選擇率을 調査하여 選擇不利에 관한 遺傳的 行動을 觀察하고자 實驗을 實施하여 아래와 같은 結果를 얻었다. 1.地球磁氣場內의 초파리 集團과 각각의 Helmholts coils裝置內 초파리 集團의 野生型 + 遺傳子의 頻度가 世代의 進行에 따라 增加하여 평형을 보여 주었다. 2.地球磁氣場內의 초파리集團과 各各의 Helmholts coils裝置內의 초파리 集團의 突然變異型 ym 遺傳子, y 遺傳子, m 遺傳子들의 頻度는 世代의 進行에 따라 減少하여 낮은 頻度의 평형을 보여 주었다. 3.초파리 集團의 發生率 變動은 地球磁氣場의 5培인 磁氣場內에서의 초파리 集團에서 3世代에 4.89%, 地球磁氣場이 消去된 곳에서의 초파리 集團에서 5世代에 12.56%로 큰 變動을 보여주었으며 相異한 磁氣場內 초파리 集團의 全體平均 發生率은 地球磁氣場內의 초파리 集團, Helmholtz coils 裝置를 이용하여 地球磁氣場이 消去된 곳에서의 초파리 集團, 地球磁氣場의 3培인 磁氣場內에서의 초파리 集團, 地球磁氣場의 5培인 磁氣場內에서의 초파리 集團에서 各各 21.59%, 23.48%, 27.79%로 地球磁氣場內의 초파리 集團에서 發生率이 增加함을 보여주었다. 4.+遺傳子를 운반한 染色體의 選擇率은 10世代까지 平均 頻度가 地球磁氣場 內의 초파리 集團, 地球磁氣場이 消去된 곳에서의 초파리 集團, 地球磁氣場의 3培인 磁氣場內에서의 초파리 集團, 地球磁氣場의 5培인 磁氣場內에서의 초파리 集團이 各各 66.11%, 61.05%, 66.12%, 66.18%로 觀察되었다. 이 結果는 地球磁氣場이 消去된 곳에서의 초파리 集團에서 가장 강한 選擇不利를 보여주었다. 5.突然變異型 ym遺傳子를 운반한 染色體의 選擇率은 各各의 조절된 磁氣場內의 초파리 集團에서 2.81%, 4.99%, 2.12%, 2.82%로 觀察되었다. 이 結果는 地球磁氣場의 3培인 磁氣場內에서의 초파리 集團에서 2.12로 相對的으로 강하게 選擇不利를 보여주었고 地球磁氣場이 消去된 곳에서의 초파리 集團에서 4.99%로 選擇不利가 가장 약하게 작용된 結果를 보여 주었다. 6.突然變異型 y遺傳子를 운반한 染色體의 選擇率은 各各의 조절된 磁氣場內의 초파리集團에서 3.73%, 3.54%, 2.57%, 2.37%로 觀察되었다. 이 結果는 地球磁氣場의 5培인 磁氣場內에서의 초파리 集團에서 더 높은 選擇不利를 보여 주었다. 7.突然變異型 m遺傳子를 운반한 染色體의 選擇率은 各各의 조절된 磁氣場內의 초파리 集團에서 3.31%, 5.66%, 4.20%, 3.87%로 觀察되었다. 이 結果는 地球磁氣場內의 초파리 集團에서 3.31%로 相對的인 강한 選擇不利를 보여 주었고 地球磁氣場이 消去된 곳에서의 초파리 集團에서 5.66%로 가장 약한 選擇不利를 보여주었다. 8.Duncan's multiple range test의 LSD값으로 有意差異 有無 檢定을 하였던 바 野生型의 A group과 突然變異型의 B group사이에 고도의 有意差異가 있음이 밝혀졌다. 9.本 實驗結果는 地球磁氣場과 여러 가지 다른 磁氣場內의 초파리 集團에서 덜 適應된 초파리로 하여금 실로 짧은 기간에 도태될 수 있게 하는 강력한 性的選擇의 예가 되는 것으로 思料된다. To elucidate the genetic behavior of selective disadventage among visible mutants of Drosophila melanogaster bred and kept by the genetic study laboratory room, Wonkwang University and the wild type collected at Sunyoudo island, and reared under the influence of four different strength of magnetic fields, i.e. the ambient, the without, the treble and the quintuple magnetic field, this study was carried out at the above indicated laboratory room. 1.The shown was that the whole mean emergence rates of the wild type Drosophila melanogaster carrying +gene - bearing chromosome was steadily increased by generation passage finally attained equilibrium, until 10th generation, under the influence of ambient and 3 different magnetic fields generated by Helmholtz coils. 2.Of the Drosophila melanogaster populations either bred in the ambient magnetic field or the magnetic fields of three different strength controlled by Helmholtz coils, the emerhence rates of mutants such as ym gene, y gene and m gene-bearing individuals were decreased with generation passage up to the tenth and also shown the equilibrium of being frequency. 3.The variations of emergence rates of Drosophila melanogaster population altering by generation showed the drastic lowest values at the specified generation, for example, 12.56% under the without magnetic field at the fifth genertion and 4.89% under the quintule magnetic field at the third gereration. The Over-all mean emergence rates of Drosophila melanogaster populations reared in controlled magnetic fields, i.e. the ambient and the without, the treble and the quintuple using Helmholtz coils, showed 21.59%, 23.48%, 27.79% and 27.14% respectively. Referring to these data, the fly population raised in the ambient magnetic field showed a relatively lower emergence rate than any one of the other three populations. 4.The mean selective frequencies of +gene-carrying chromosome up to tenth generation, affected by four different magnetic fields, showed 66.11%, 61.05%, 66.12% and 66.18% with the magnetic field strength as mentioned order before. The data explains that Drosophila melanogaster population reared in the without magnetic field showed the highest selective disadventage. 5.The selective frequencies of the individual of ym gene-bearing chromosomes showed 2.81%, 4.99%, 2.12% and 2.82% by the same order of magnetic field strength indicated above. It was shown that the fly population reared at the treble strength generated by Helmholtz coils cleared the relatively strong selective disadvantage being 2.12%, however the opposite value was 4.99% resulted form the without magnetic field. 6.The selective frequencies of the mutant which carries y gene-bearing chromosome showed 3.73%, 3.54%, 2.57% and 2.37% from the four different magnetic fields in the same magnetic order. The results indicate that the fly population form the quintuple magnetic field showed the higher selective disadvantage frequency, 2.37%. 7.The selective frequencies for the mutants carrying m gene-bearing chromosome were calculated as to be 3.31%, 5.66%, 4.20% and 3.87% for the same order of magnetic field strength. The found from this results is that the selective disadvantage frequency for the mutant rearing ym gene chromosome in the ambient magnetic field was stronger than any one of the other, being 3.31%, however the opposite value was resulted from the without magnetic field 5.66%. 8.Through Duncan's multiple range test and LSD value, the highly significant differences between the wild type and any one of the other three mutants were calculated. 9.As the conclusion obtainable from this experiments, the results indicated that such sexual selection was strong enough to eliminate the less "fit" flies bred under the magnetic field impact in a remarkably short span of time, even for the period of tenth generation is not long enough.

한국 초파리집단의 선택불리에 관한 지구 자기장의 5배인 자기장의 영향

박은규,정승문,김중현,최오목 圓光大學校 1995 論文集 Vol.29 No.2

본 연구에서는 한국 선유도의 자연집단 야생형 초파리와 가시돌연변이형 황색체-소시 초파리를 Helmholtz coils 장치를 이용해서 유도한 지구 자기장의 5배인 자기장내의 집단과 비교 집단인 지구 자기장내의 집단에서 발생율 변동과 성적 선택빈도를 조사하여, 선택불리에 관한 유전적 행동을 관찰해서 다음과 같은 결과를 얻었다. 1.야생형 유전자(+)를 운반하는 염색체의 선택빈도는 15세대까지 평균 빈도가 지구 자기장의 5배인 자기장내의 초파리 집단, 지구 자기장내의 초파리 집단이 각각 0.6489, 0.6553으로 관찰되었다. 이 결과는 지구 자기장의 5배인 초파리 집단에서 더 강한 선택불리 행동을 보여 주었다. 2.초파리 집단의 발생율 변동은 지구 자기장의 5배인 자기장내의 초파리 집단 3세대(13.60%), 지구 자기장내의 초파리 집단 6세대(22.35%), 8세대(22.30%)에서 아주 낮은 발생율의 변동을 보여주었으며, 2개의 상이한 자기장내 초파리 집단의 전체 평균 발생율은 지구 자기장의 5배인 자기장내의 초파리 집단, 지구 자기장내의 초파리 집단에서 각각 58.07%, 41.93%로 관찰되었으며, 후자보다 전자에서 발생율이 증가함을 보여 주었다. 3.돌연변이형 황색체-소시 유전자(ym)를 운반한 염색체의 선택빈도는 각각의 자기장내의 초파리 집단에서 0.0542, 0.0646으로 관찰되었다. 이 결과는 지구 자기장의 5배인 자기장내의 초파리 집단에서 0.0542로 상대적으로 강하게 선택불리 행동을 보여 주었다. 4.돌연변이형 황색체 유전자(y)를 운반한 염색체의 선택빈도는 각각의 초파리 집단에서 0.0185, 0.0144로 관찰되었다. 이 결과는 비교 집단인 지구 자기장내의 초파리 집단에서 0.0144로 더 강한 선택불리 행동을 보여 주었다. 5.돌연변이형 소시 유전자(m)을 운반한 염색체의 선택빈도는 각각의 조절된 자기장내의 초파리 집단에서 0.0328, 0.0190으로 관찰되었다. 이 결과도 지구 자기장내의 초파리 집단에서 0.0190으로 상대적인 강한 선택불리 행동을 보여 주었다. 6.수컷이 가지고 있는 Y-염색체의 선택빈도는 각각의 초파리 집단에서 0.2457, 0.2467로 관찰되었다. 이 결과는 지구 자기장의 5배인 초파리 집단에서 0.2457로 더 높은 선택불리 행동을 보여 주었다. 7.Duncan's multiple range test의 LSD값으로 유의 차이 유무 검정을 하였던 바 야생형 유전자의 A 그룹과 돌연변이형 유전자들의 B 그룹사이에서 고도의 유의 차이가 있음이 밝혀졌다. To elucidate the genetic behavior of selective disadvantage among visible mutants of Drosophila melanogaster bred and kept by the genetic study laboratory room. Wonkwang University and the wild type collected at Sunyoudo island in Korea, and reared under the influence of two different strength of magnetic fields, i.e. the quintuple and the ambient magnetic field, this study was carried out at the above indicated laboratory room. 1.The mean selective frequencies of wild gene(+)-carry chromosome up to 15th generation, affected by two different magnetic fields, showed 0.6489 and 0.6553 with the magnetic field strength as mentioned order before. The data explains that the population of Drosophila melanogaster reared in the quintuple magnetic field showed higher selective disadvantage. 2.The variations of emergence rates of the populations of Drosophila melanogaster altering by generation showed the drastic lowest values at the specified generation, for example, 13.60% under the quintuple magnetic field at the third generation and 22.35% and 22.30% under the ambient magnetic field at the 6th and 8th generation. The over-all mean emergence rates of the populations of Drosophila melanogaster reared in controlled magnetic fields, i.e. the quintuple and the ambient magnetic fields using Helmholtz coils, showed 58.07% and 41.93% respectively. Referring to these data, the population of flies raised in the quintuple magnetic field showed a relatively higher emergence rate than the ambient magnetic field. 3.The mean selective frequencies of the individual of ym gene-bearing chromosomes showed 0.0542 and 0.0646 by the same order of magnetic field strength indicated above. It was shown that the population of flies reared in the quintuple strength generated by Helmholtz coils cleared the relatively strong selective disadvantage being 0.0542. 4.The mean selective frequencies of the mutant that carries y gene-bearing chromosome showed 0.0185 and 0.0144 from the two different magnetic fields in the same magnetic order. The results indicated that the population of flies from the ambient magnetic field showed higher selective disadvantage frequency, 0.0144. 5.The mean selective frequencies for the mutant carrying m gene-bearing chromosome were calculated as to be 0.0328 and 0.0190 for the same order of magnetic field strength. The found from this results is that the selective disadvantage behavior for the mutant rearing m gene chromosome in the ambient magnetic field was stronger than the one, being 0.0190. 6.The mean selective frequencies of the male flies which carries Y-chromosome showed 0.2457 and 0.2467 respectively. The results indicated that the male flies from the quintuple magnetic field showed higher selective disadvantage being 0.2457. 7.Through Duncan's multiple range test and LSD value, the highly significant differences between A group of the wild type and B group of the other three mutants were calculated.

光多變色 초파리 迷路集團의 性的 選擇利益에 관한 遺傳的 行動

朴殷圭,金在淳,崔五木 圓光大學校 1992 論文集 Vol.26 No.2

光多變色 迷路集團裝置를 사용하여 4가지 色光에 대한 초파리의 性的 選擇利益에 따른 光鮮好性 差異의 形質을 分析하고자 實驗하였다. 光多變色 迷路集團裝置 속에 野生型 초파리와 突然變異型 黃色體-小翅 초파리를 各各 50쌍씩 즉, 암·수 各各 25%씩을 混入하여 그후 異型接合體 野生型 암컷의 交叉에 의해서 出現된 突然變異型 黃色體 초파리와 小翅 초파리를 同時에 觀察하였던 바, 各 色光 房 초파리 集團마다 差異는 있었으나 모든 경우에서 野生型 초파리의 選擇利益率이 增加하고 突然變異型 초파리의 選擇利益率은 減少하는 傾向이었다. 各 色光 房 野生型 초파리의 +遺傳子를 운반한 染色體의 性的 選擇利益率은 25世代까지 全體 平均 頻度가 黃色光 房에서는 64.20%, 赤色光 房에서는 64.36%, 靑色光 房에서는 65.42%, 暗色光 房에서는 61.74%로 나타났다. 이러한 實驗結果는 陽性 走光性 步行行動을 나타낸 靑色光 房 초파리 集團의 性的 選擇利益率(65.42%)의 效率이 가장 강했음을 보여 주었고 반면에 陰城 走光性 步行行動을 나타낸 暗色光 房의 초파리 集團은 그 效率(61.74%)이 比較的 약한 것으로 觀察되었다. 한편 野生型과 突然變異型 모든 초파리가 各 色光 房의 光鮮好性에 따른 步行行動에 의한 發生率은 各各 25%로 시작했던 實驗이 25世代까지 全體平均 發生率은 黃色光 房, 30.41%; 赤色光 房, 23.24%; 靑色光 房, 41.96%; 暗色光 房과 4.38%로 算定되었다. 이런 實驗結果를 中立値 頻度 25%로 分析하여 보면 黃色光 房과 靑色光 房의 초파리 發生率은 各各 5.41%와 16.96%의 陽性 遺傳率을 보였고 赤色光 房과 暗色光 房에서는 各各 -1.76%와 -11.62%의 陰城 遺傳率로 觀察되었다. 이런 現象은 모든 초파리가 靑色光을 가장 鮮好하고 다음으로 黃色光, 赤色光, 暗色光 순으로 鮮好한다는 것을 보여준 것으로 思料된다. A study on the difference of photo-preference subjected to sexually selective advantage of Drosophila melanogaster in four light chambers was carried out. Each 25% of the wild type and the visible mutants(the yellow bodied-miniature winged) of male and female flies put into the photo-varicolored labyrinth population apparatus. The yellow bodied and the miniature winged mutants were observed by crossing over in the wild type heterozygous female flies. In all cases the selective advantage of the wild type increased and that of the mutants decreased. The sexually selective advantages of +gene bearing chromosome of the wild type in each light chamber were observed as 64. 20% in the yellow light chamber for the whole average frequency through initial to twenty-five generations. as 64.36% in the red light chamber, as 65.42% in the blue light chamber and as 61.74% in the dark light chamber respectively. These results showed that the efficiency of the sexually selective advantage(65.42%) of the blue chamber flies group was appeared high in the walking behavior of the positive phototaxis but to the contrary the flies group in the dark chamber showing negative phototaxis was observed as comparably weak (61.74%). On the other hand, the developmental ratio of all the wild type and the mutants by their walking behavior subjected to photo-preference of each chamber was computed to be of 30.41% in entire average through initial to twenty-five generations in the yellow chamber, 23.24% in the red chamber, 41.96% in the blue chamber, and 4.30% in the dark chamber respectively. As such results were analyzed by the neutral frequency (25%), the developmental ratio of files of the yellow and the blue chambers showed 5.41% and 16.96% respectively as positive realized heritability and in the red and the dark chamber it was observed as -1.76% and -11.62% respectively as negative realized heritability. All these results indicated that all the flies prefered the blue, yellow, red and dark light in order.

老子 無爲思想의 基底

최오목(Choe Oh Mok) 한국도교문화학회 2011 道敎文化硏究 Vol.34 No.-

노자는 인간과 자연을 대립적으로 보지 않고, 합일적통합적 관점에서 인간과 자연의 문제를 파악하고 있다는 점이다. 노자는 천지만물의 움직임은 모두 자연스럽게 진행되지만 인간의 행위만큼은 그러하지 못하고, 인간만이 유일하게 자연을 그와 대립된 하나의 대상으로 바라보는 잘못을 범하고 있다고 지적하고, ‘無爲’를 주장한 것이다. 노자의 ‘無爲’를 심리적인 측면에서 볼 때, 이는 자신의 의식세계의 부정적인 ‘無’를 통해 무의식의 絶對知로부터 나오는 자연스럽고 성숙된 ‘能爲’를 이끌어낼 수 있는 것으로 해석할 수 있다. 이렇게 이끌어낸 ‘能爲’는 본래적으로 부여된 자연과의 조화 및 균형을 회복하게 되는 것인 바, 노자는 이러한 ‘無爲自然’의 처방을 통해 당시 사회의 모든 모순과 문제를 개선하고, 치유하고자 했던 것이다. 현대생물학적 측면에서 노자의 사상을 분석해 볼 때, 노자의 ‘無爲自然’의 처방은 특히 구조와 기능이 발달된 인간의 대뇌 전두엽의 기능을 절제 시키는 생리 작용에 효과가 있다고 본다. 노자는 ‘聖ㆍ智ㆍ仁ㆍ義ㆍ巧ㆍ利’와 같이 인간이 선호하는 세속적 가치들을 끊어버리라고 말한다. 이는 미성숙한 자세로 성급하게 세속적 가치를 추구하다 보면 본성을 잃게 되므로, 절대적이며 자연적인 ‘聖ㆍ智ㆍ仁ㆍ義ㆍ巧ㆍ利’를 능숙하게 추구하며, 서서히 실천하라는 의미인 것이다. 따라서 노자의 부정어의 사용은 보다 더 높은 차원의 절대적 긍정을 이끌어내려는 것으로서, 성숙한 能爲를 전제하고 있는 것이다. 이러한 ‘無爲自然’의 ‘能爲’는 생물학적으로 자율신경계의 생리적 이탈을 막아주는 작용에 영향을 줄 수 있기 때문에, 이러한 사상은 모든 생명체를 지켜주는 무위사상의 핵심이 된다고 본다. 특히 노자가 말하는 聖人은 곧 ‘자연의 본성과 하나 된 인간’으로, 道를 체득하여 天地萬物에 피해를 주지 않는 인간 즉, 사사로움을 넘어 至公無私함을 지향하며, 천지자연의 이치에 부합된 노자 의 ‘聖人’을 통해 바람직한 무위사상의 기저를 이끌어내고자 하였다.

교량의 자동화 균열 검출능 향상을 위한 딥러닝 기반의 초고해상도 디지털 이미지 생성 기술

배현진(Bae, Hyun Jin),장근영(Jang, Kuen Young),안윤규(An, Yun-Kyu) 대한토목학회 2020 대한토목학회 학술대회 Vol.2020 No.10

베이스 커브에 의한 콘택트렌즈 피팅 효과

최오목,강명진 대한시과학회 2000 대한시과학회지 Vol.2 No.2

콘택트렌즈 피탱후 기초검사와 베이스커브의 무작위 피탱검사, 그리고 베이스커브 의 의도적인 변화에 따룬 재피팅검사을 이용하여 중함수의 소프트 콘택트렌즈의 피 팅과 베이스커브의 효과에 대하여 조사하였다. 시험렌즈 피팅후 렌즈의 위치, 순목후 렌즈의 움직임, 자각적 착용감을 평가하여 적합한 베이스 커브를 평가한 결과 본 연 구에 사용한 소재의 소프트 콘태트렌즈에서는 베이스커브가 8.4 mm의 경우 최상의 피탱 효과를 보였다. 베이스커브를 8.4 mm보다 큰 정우 순복후 렌즈 움직임보다 피 팅후 렌즈의 중심이탈정도가 섬하고 자각적 검사결과 의도적인 재피탱을 시도하였다. 다른 제조회사렌즈는 정교한 디자인과 제조상의 차이 때문에 언제나 같은 방법으로 피팅 결과가 나오눈 것은 아니다 본 실험에 사용한 중함수율 소프트콘택트렌즈는 대 다수의 눈에 최적의 피팅을 제공해 주는 것은 8.4mm 베이스 커브 렌즈가 효과적이 었다. The study investigated the effects of base curve radius on the fit of thin, mid-water contact lenses. It was found that central comeal curvature (as measured with the keratometer) was not predictive of the best fitting base curve. Lenses made from vifilcon A (the material used for Focus 1-2 weeks) tended to be most successful. When fit with the 8.4mm lens. For most eyes, fitting a f1atter vifilcon lens led to greater decentration, decreased comfort, and no increase in lens movement. The focus 1 - 2 weeks 8.4mm lens was found to provide on “ optimal" fit in over 60% of eyes tested and a fit of “good" or “better" in nearly 90% of eyes tested. Comparisons of different manufactures' lens found that similiar lenses do not always fit in the same way due to subtle design and production differences. Therefore. differemt products may require different base cuπes to best fit the same patient. This was true even when water content. diameter. and center thickness were approximately the same.

광 다변색 미로장치에 의한 초파리의 광선호성 차이에 관한 연구

최오목(Oh Mok Choe) 원광대학교 생명자원과학연구소 1996 농대논문집 Vol.19 No.-

베이스 커브에 의한 콘택트렌즈 피팅 효과

최오목(Oh Mok Choe),강명진(Myoung Jin Gang) 한국안광학회 2000 한국안광학회지 Vol.5 No.2

The study investigated the effects of base curve radius on the fit of thin, mid-water contact lenses. It was found that central corneal curvature(as measured with the keratometer) was not predictive of the best fitting base curve. Proper lens fit may be the single most important factor that ultimately determines the success of contact lens wear. Comfort, vision, and physiological response are all dependent on the fit of the lens. The percent of optimal fits was highest with the 8.4 ㎜ base curve lens for all three ranges of keratometry values. When fit with the 8.4 ㎜ lens. For most eyes, fitting a flatter lens led to greater decentration. decreased comfort, and no increase in lens movement. The 8.4 ㎜ lens was found to provide on $quot;optimal$quot; fit in over 60% of eyes tested and a fit of $quot;good$quot; or $quot;better$quot; in nearly 90% of eyes tested. Comparisons of different manufactures` lens found that similar lenses do not always fit in the same way due to subtle design and production differences. Therefore, different products may require different base curve radii to fit the same patient. This is even true when water content, center thickness, and diameter are approximately the same. A practitioner fitting a new patient in this lenses should begin with the 8.4 ㎜ base curve radius.