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이윤종 ( Yun Jong Lee ),최영주 ( Young Joo Choe ),이은봉 ( Eun Bong Lee ),김현아 ( Hyun Ah Kim ),송영욱 ( Yeong Wook Song ) 대한류마티스학회 2000 대한류마티스학회지 Vol.7 No.3
Wegener`s granulomatosis is a serious multi-systemic disease pathologically characterized by necrotizing vasculitis and granuloma. Although nervous system is one of major target organs in Wegener`s granulomatosis, the involvement of facial nerve was rarely reported as an initial symptom. We experienced a female patient with Wegener`s granulomatosis presenting otitis media, sinusitis and right facial palsy. Nasal mucosal biopsy revealed necrotizing vasculitis with granuloma formation, which was consistent with Wegener`s granulomatosis. During steroid and cyclophosphamide therapy, she developed paralysis of abducens nerve. Methyprednisolone pulse therapy was administrated with symptomatic improvement. We describe a case of Wegener`s granulomatosis presenting facial nerve palsy.