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최봉혁(Bong-Hyuk Choi),김종배(Jong-Bae Kim),도명술(Myoung-Sool Do) 한국식품영양과학회 2005 한국식품영양과학회지 Vol.34 No.10
With the decoding of human genome in 2004 and the recent development in nutritional science, there has been an integration of molecular biology and nutrition. As a consequence a new word “molecular nutrition” has been formed and recently the word ‘nutrigenomics’ is coined and widely being used. The field of science that showed the most positive result from grafting the science of nutrition and nutrigenomics is obesity. In 1994, Jeffrey Friedman from Rockeffeler University announced that ob gene and obesity has a close relationship and since then there’s been a huge research done on genes related to obesity from the molecular nutrition’s point of view. Even now there are many genes presented which are supposed to be related to obesity and big efforts are put into finding what exactly those genes do. Moreover studying only in the context of genes was not enough so functional genomics, which is the study of the functions of cells and the functions and effects between genes and protein products, is being studied. This review article discusses the relationship between nutrition and genes and the general idea of nutrigenomics. The article also discusses about the current research status on these subjects.