http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
양성자 화학적 이동영상기법(<sup>1</sup>H-CSI)을 이용한 정위적 뇌생검
장경술,손병철,김문찬,최병길,김의녕,김범수,최보영,백현만,홍용길,강준기,Chang, Kyung-Sool,Son, Byung-Chul,Kim, Moon-Chan,Choi, Byung-Gil,Kim, Euy-Neying,Kim, Bum-Soo,Choe, Bo-Young,Baik, Hyun-Man,Hong, Yong-Kil,Kang, Joon-Ki 대한신경외과학회 2000 Journal of Korean neurosurgical society Vol.29 No.12
Objective : To obtain more reliable sample in stereotactic biopsy, authors adopted proton chemical shift imaging ($^1H$-CSI)-directed biopsy. Until now, proton single voxel spectroscopy($^1H$-SVS) technique has been reported as a technique using metabolic information in stereotactic biopsy. The authors performed $^1H$-CSI with a stereotactic headframe in place and evaluated the pathologic results obtained from local metabolic information through $^1H$-CSI. Methods : $^1H$ CSI-directed stereotactic biopsy was performed in four patients. $^1H$-CSI and conventional Gd-enhancement stereotactic MRI was done simultaneously after application of the stereotatic frame. After reconstruction of metabolic maps of NAA/Cr, Cho/Cr, and Lactate/Cr ratios, the focal areas of increased Cho/Cr ratios and decreased NAA/Cr ratios were selected for target sites in the MR images Results : There was no difficulty in performing $^1H$-CSI with the stereotactic headframe in place. In pathologic examinations, the samples taken in area of increased Cho/Cr ratios and decreased NAA/Cr ratios showed the features of increased cellularity, mitoses and cellular atypism, thus facilitated the diagnosis. The pathologic samples taken from the area of increased Lactate/Cr ratios showed prominent feature of necrosis. Conclusion : $^1H$-CSI was feasible with stereotactic head frame in place. The final pathologic results obtained in our samples were concordant with the local metabolic informations from $^1H$-CSI. Authors believe that $^1H$ CSI-directed stereotactic biopsy may provide us advantages in obtaining more reliable tissue specimen in stereotactic biopsy.
윤수정,박종욱,최병길 啓明大學校 醫科大學 1996 계명의대학술지 Vol.15 No.4
면역계의 생리기능은 self와 nonself의 식별로서, 외부 물질에 대한 자신의 방어 기전으로 정의될 수 있다. 면역계는 골수 lymphocyte인 B cell과 흉선 lymphocyte인 T cell로 구성되며, 이들은 여러 가지 apoptosis 관련 유전자들에 의해 그 수가 조절된다. 흉선이나 골수에서의 분화 성숙 과정에서는 Bcl-2계 유전자가, 말초에서 일어나는 autoreactive T cell 및 B cell 의 제거에는 Fas/fas ligand 유전자가 각각 관여하는 것으로 밝혀졌다. 그리고 세포성 면역 반응이 최고에 이른 후 항원특이 세포들의 수가 점차 사라지는 과정, 즉 activation-induced cell death 역시 Fas/Fas ligand 및 TNF/TNF receptor 등의 유전자에 의해 조절되는 것으로 알려졌다. 본 논문에서는 면역세포들의 생존을 조절하는 apoptosis 관련 유전자들에 대해 최신 연구를 중심으로 요약하고자 한다.
崔炳吉 慶北大學校 醫科大學 1961 慶北醫大誌 Vol.3 No.2
Author investigated acetate oxidation of Escherichia Coli 0111 strain by employing the manometric technique and foregoing results were obtained. With these results, it was concluded that: ⑴ Acetate oxidation of E. Coli 0111 belongs to so called Oxidative Assimilation. i, e. CH_2COOH+1,5O_2=1,5CO_2+1,5H_2O+0,5(CH_2O) Though what the compound expressed in(CH_2O) might be was not identified directly, through the determination of alkaline soluble sugar contents of Acetate oxidining cells andcontrol cells, it was qualititatively assured that a portion of acetate is assimilated into the bacterial cell as the sugar, ⑵ By applying the principle of simultaneous adapltation, it was partly concluded that E. coli contains the enzymes neccessary for the oxidation of such compounds occurring in Krebs cycle as succinate fumarate, malate etc. ⑶ Using the tetracycline as an ibhibitor, it was shown that tetracycline did not exhibit any appreciable offect on the Acetate and succinate oxidation of E. coli in the concentration of 200 microgram per mililiter.