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원판상 홍반성 루프스에서 발생한 거대한 극세포암의 1예
김명열,차종식,김형배,손영호 대한피부과학회 1982 大韓皮膚科學會誌 Vol.20 No.6
In the past, irritant or radiation therapy have been used to treat discoid lupus erythematosus, therefore malignant and proriferative change in the lesion of discoid lupus erythematosus were not uncommon. In recent year, however, because the preferred treatment of discoid lups erythematosus consisted of steroids and antimalarials, the association with squamous cell carcinoma has been extremely rare. We present a case of giant squamous cell carcinoma arising in the discoid lupus erythematosus in 39 year-old women. She had had a 20 year history of facial discoid lupus erythematoseus. In September of 1976, a thumb tip-sized tumor mass found on the right cheek and the maas grew into the adult palm size rapidly. The tumor show ulceration, serosanguinous discharge, easy bleeding, and foul oder. Histopathologically, the specimen obtained from plaques of the left cheek showed hyperkeratosis with plugging, atrophy of the stratum malpighii, a patchy, chiefly lymphoid cell infiltrate with a tendency to arrangement about the cutaneous appendages, hydropic degeneration of the basal cells, edema and vasodilatation in the dermis. The specimen obtained from tumor mass of the right cheek showed many nests consisted of well differentiated squamous cells, keratin pearls.
건선의 임상적 고찰(I) : 충청지방 건선환자의 임상적 고찰
박장규,차종식 충남대학교 의과대학 지역사회의학연구소 1982 충남의대잡지 Vol.9 No.2
Psoriasis is bright red or silvery white scaly disease, affecting 0.1% to 3.6% of general population in the world. This study was aimed to investigate the clinical manifestations and clinical incidence of psoriasis and was based on analysis of 50 patients with psoriasis seen between October, 1981 and October, 1982 at the Department of Dermatology, Chungnam National University Hospital. The results summerized as follows: 1. Of the 50 patients in this series 28(56%) were male and 22(44%) were female. 2. The mean age of onset in male was 27.1 years and in female it was 18.1 years. The peak age of incidence in male was between 20 and 29 years and in female between 10 and 19 years. 3. 14(28%) in this series had the families with psoriasis in history. 4. The mean duration of the disease for the total sample was 7.1 years, ranging from 6 months to 30 years. 5. Of the 50 patients :in this series 40(80%) showed seasonal variations in their clinical courses. Majority of them(85%) improved during summer. 37 patients(74%) experienced Koebner phenomenon once or more. 6. Spontaneoue and complete remission was experienced by 20(40%) of the patients during the diseases. 7. Itching as a subjective symptom of psoriasis was observed in 36(72%) of ,the patients, and the most patients of them complained mild itching. Severe itching was complained of in 4(11%) of the patients. 8. Arthalgia was complained of 5(10%) of the patients. 9. At the onset following sites were affected in descending order of frequency: scalp (24%), elbow joint(23%), lower extremity(20%), knee joint(20%), trunk(17%), upper extremity(15%), face(8%). Over the course of the disease(average 7. 1 years), the sites affected were lower extremity (84%), upper extremity(82%), trunk(75%), knee joint(74%), scalp(70%), face(40%), in order of frequency.
김윤성,구본길,차종식,박장규,이영 충남대학교 의과대학 지역사회의학연구소 1984 충남의대잡지 Vol.11 No.1
Mondor's disease has been regarded as an obliterative phlebitis usually affecting superficial vein of the chest wall. It is characteristic that the cord-like thrombosed vein which is red and tender at first changes into painless fibrous band. In the past, it was confused with lymphatic spread of carcinoma but it was confirmed that it was benign and related with the systemic diseases or cancer. The authors observed a 57-year-old female with Mondor's disease. 15 days ago, she notified the cord-like lesion on the right chest well, from right axillar fold to right iliac crest. 1. month later, the skin lesion much improved without special treatment.