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차성재,박성준,Seong Jae Cha,M,D,and Sung Jun Park,M,D 대한갑상선-내분비외과학회 2003 The Koreran journal of Endocrine Surgery Vol.3 No.1
The authors present a clinical analysis of 69 cases of primary hyperparathyroidism during the last 32 years from 1963 to 1994 which were reported in Korean Medical Journals. There were 69 patients, 21 males and 48 females, with a male to female ratio of 1 to 2.3. The age distribution was between 4 months and 65 years. The presenting clinical manifestations were musculoskeletal symptoms (66.7%), renal symptoms (49.3%), and general weakness (21.7%) in that order of frequency. There were 2 patients with asymptomatic hypercalcemia. The mean preoperative serum Ca and P levels were 13.1 mg% and 2.4 mg%. The mean postoperative serum Ca and P levels were 8.0 mg% and 2.7 mg%. The mean preoperative and postoperative PTH levels were 3275 pg/dl (normal range; 220∼660 pg/dl) and 392 pg/dl. Preoperative localization was done using ultrasonogram, computed tomogram, thallium-technetium subtraction scan, and arteriogram. Positive localization was made in 84.8% (28/33), 72.7% (24/33), 84.2% (16/19), and 100% (9/9), respectively. In one patient, magnatic resonance imaging was performed and positive localization was made. The location of the lesion was more common in the lower part of thyroid than the upper part and on the left side rather than the right side. There were 7 patients with ectopic locations including the thoracic inlet (2), intrathymus (1), intrathyroidal (1), mediastinum (2), and right subclavicular (1). All patients were treated surgically. The final histopathologic findings were single adenoma in 63, carcinoma in 3, and primary hyperplasia in 2 patients. There was 1 patient with double tumors composed of adenoma and carcinoma. (Korean J Endocrine Surg 2003;3:32-38)
차성재(Seong Jae Cha),박성준(Sung Jun Park),임현묵(Hyen Muck Lim) 대한두경부종양학회 1997 대한두경부 종양학회지 Vol.13 No.2
결론적으로 저위험군환자에서는 수술방법 및 수술후 보조적인 치료법인 방사선요드동위원소 치료 및 갑상선 흐르몬 억제 치료가 생존을 증가에 별다른 영향을 주지 않으리라 생각된다. 이러한 이유는 사실상 이들 환자에서는 사망률의 위험성이 거의 없어 생존율을 확인할 방법이 없기 때문이다. 따라서 저위험군에서는 광범위한 수술방법을 피하고 고위험군에서는 환자 개개인의 상태에 따라 수술방법이 선택되어야 하며 갑상선 전절제술은 확실한 예후의 증가나 다른 적절한 치료 방법이 없을 경우 조심해서 선택되어야 된다고 사료된다. Background: There is considerable controversy concerning the most appropriate surgical treatment of patients with DTC. Objectives: In order to selection of the appropriate surgical treatment for DTC, we have analyzed the outcome of the different types of surgical treatment in low and high risk groups of DTC. Materials and Methods: From January 1968 through december 1980, a total of 71 patients with DTC were treated surgically at our institution. According to Cady and Rossi's scoring system, the patients were divided into low risk and high risk groups. Results: Seventy percent of patients were defined as low risk group with a 4% death rate whereas 30% of patients at high risk with a death caused by thyroid cancer in 38%(p<0.05). There was no difference in mortality between ipsilateral lobectomy and total thyroidectomy in both low and high risk groups(p>0.1). Conclusion: In our study, total thyroidectomy was not benefit in high risk group. These results suggested that total thyroidectomy must be selected carefully and based on clear evidence of major improvement in outcome or absence of other suitable surgical approaches. However, follow up study of more cases will be needed for accurate determination of the efficacy of total thyroidectomy in high risk group.
이성민(Sung Min Lee),장인택(In Taik Chang),김범규(Beom Gyu Kim),차성재(Sung Jae Cha) 대한외과학회 2007 Annals of Surgical Treatment and Research(ASRT) Vol.72 No.6
Morgagni hernia is known as the smallest form of diaphragmatic hernia and it is usually asymptomatic. However, almost all the cases reported in the Korean literature have been symptomatic and they were surgically repaired. The authors report here on a case of Morgagni hernia that was found accidentally during the preoperative workup of a patient who suffered from panperitonitis with cecal perforation. The patient was transferred from the local hospital with complaints of pain in the entire abdomen. On the preoperative CT, a large paracardial mass and a collection of intra-peritoneal free air were identified. After reduction of the hernia contents, the hernia was repaired with using mesh. The patient showed a rapid recovery without any complication.
대장암에서 CD31과 D2-40 발현에 의한 혈관성 및 림프관성 미세혈관 밀도 측정
윤상인(Sang In Youn),김범규(Beom Gyu Kim),차성재(Seong Jae Cha),박성준(Sung Jun Park),장인택(In Taek Chang),박성일(Sung Il Park),이태진(Tae Jin Lee) 대한외과학회 2007 Annals of Surgical Treatment and Research(ASRT) Vol.73 No.4
Purpose: Angiogenesis and lymphangiogenesis play important roles in the growth, progression and metastasis of colon cancer. We performed this study in order to investigate the significance of the CD31 and D2-40 expressions as prognostic factors in colon cancer. Methods: The angiogenic and lymphagiogenic microvessel density was assessed by immunohistochemical staining of CD31 and D2-40 on samples that were resected from 66 patients with colorectal cancer. Results: Strong correlation was observed between the CD31 microvessel density and being positive for having tumor emboli and lymph node metastasis (P=0.001, P=0.003). The D2-40 lymphatic vessel density was correlated with being positive for having tumor emboli (P=0.0001), the depth of invasion (P=0.0001), lymph node metastasis (P= 0.0001) and the cancer stage (P=0.0001). The D2-40 lymphatic vessel density was also correlated with the CD31 count (P=0.003). Conclusion: These results suggested that the CD31 and D2-40 expressions are useful predictors of lymph node metastasis and they are prognostic factors for colon cancer.