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대장암에서 CD31과 D2-40 발현에 의한 혈관성 및 림프관성 미세혈관 밀도 측정
윤상인(Sang In Youn),김범규(Beom Gyu Kim),차성재(Seong Jae Cha),박성준(Sung Jun Park),장인택(In Taek Chang),박성일(Sung Il Park),이태진(Tae Jin Lee) 대한외과학회 2007 Annals of Surgical Treatment and Research(ASRT) Vol.73 No.4
Purpose: Angiogenesis and lymphangiogenesis play important roles in the growth, progression and metastasis of colon cancer. We performed this study in order to investigate the significance of the CD31 and D2-40 expressions as prognostic factors in colon cancer. Methods: The angiogenic and lymphagiogenic microvessel density was assessed by immunohistochemical staining of CD31 and D2-40 on samples that were resected from 66 patients with colorectal cancer. Results: Strong correlation was observed between the CD31 microvessel density and being positive for having tumor emboli and lymph node metastasis (P=0.001, P=0.003). The D2-40 lymphatic vessel density was correlated with being positive for having tumor emboli (P=0.0001), the depth of invasion (P=0.0001), lymph node metastasis (P= 0.0001) and the cancer stage (P=0.0001). The D2-40 lymphatic vessel density was also correlated with the CD31 count (P=0.003). Conclusion: These results suggested that the CD31 and D2-40 expressions are useful predictors of lymph node metastasis and they are prognostic factors for colon cancer.
온라인 필기인식에 관한 방법연구와 이를 활용한 응용프로그램 제작
윤상인;유진식;공희경;김흥식 인제대학교 2012 仁濟論叢 Vol.27 No.1
Recently with the spread of smart phones is increasing the importance of handwriting recognition technology. Therefore, we studied these online handwriting recognition technology for real-time input. In this research process we study the distance filtering method, the catching feature points, chain code, and similarity matching techniques and make possible the actual coded. We implemented the on-line symbol recognition method which recognize up to 91% of the capital letter. That you can use handwriting recognition to target programs, the children learn to play program planning and production.