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- 저자 : 진기천(Kee Chun Jean) (검색결과 2 건)
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박경태(Kyung Tae Park),박희상(Hee Sang Park),진기천(Kee Chun Jean),이시억(Si Eok Lee),권혁(Hyuk Kwon),김기현(Ki Hyun Kim) 대한내과학회 1989 대한내과학회지 Vol.37 No.2
N/A To investigate the characteristics of the laboratory findings of minimal change nephrotic syndrome (MCNS), we analysed retrospectively the laboratory findings of 43 patients with MCNS confirmed by renal biopsy, and we also studied those of 20 patients with nephrotic syndrome of other histopathologic finding as the control group. The characteristics of the laboratory finding of MCNS were as follows: 1) On urinalysis, the total amount of urine protein per day in MCNS patients was 10.0±6.8 gm and this showed a significantly increased value compared with the control group value of 6.3±3.5 gm (p<0.01), and the cases of severe proteinuria above 11 gm/day were more frequent in MCNS patients (34.8%) than in the control group (10.0%). 2) Serum total protein value was 4.1±0.9 gm/dl in MCNS patients and 4.7±1.2 gm/dl in the control group and was slightly lower in MCNS patients than in the control group. The serum albumin value in MCNS patients was 1.8±0.7 gm/dl and showed a significantly decreased value compared with 2.5±0.8 gm/dl in the control group (p<0.01), and the cases of severe hypoalbuminemia below 1.5 gm/dl were more frequent in MCNS patients (46.5%) than in the control group (15%). 3) On blood lipid study, total cholesterol, LDL and VLDL values in MCNS patients were 461.4±155.2 mg/dl, 988.2±539.0 mg/dl and 341.4±198.8 mg/dl and showed a significant increase compared with the control group values of 336.4±132.5 mg/dl, 632.1±291.2 mg/dl and 187,2±147.7 mg/dl respectively (p<0.01, p<0.05, p<0.05). 4) BUN was 22.9±15.9 mg/dl in MCNS patients and 16.8±7.0 mg/dl in the control group and was significantly increased in MCNS patients compared to the control group (p<0.05). There was no difference between MCNS patients and the control group in serum creatinine value and creatinine clearance rate. 5) Hemoglobin and hematocrit in MCNS patients were 15.5±1.5 gm/dl and 45.6±5.2% respectively and showed a significantly increased over the control group values of 13.1±1.9 gm/gl and 37.9±5.6% respectively (p<0.01, p<0.01). There were 11 cases of eosinophilia among 43 MCNS patients (25.6%) but there were no cases in the control group. 6) The positive rate of HBsAg in MCNS patients was 11.6% and showed a lower value compared with the control group value of 35.0%. 7) Serum IgG in MCNS patients was 493±266 mg/dl and showed a significantly decreased value compared with the control group value of 871S613 mg/dl (p<0.0l). IgM in MCNS patients was 197±82 mg/dl and this was significantly increased compared with the control group value of 141±63 mg/dl (p<0.05), and the IgE value was more increased in MCNS patients (678S385 mg/dl) than in the control group (544±378 mg/dl) (p>0.05). The C3 value was 96±20 mg/dl in MCNS patients and 75±19 mg/dl in the control group and it was significantly increased in MCNS patients compared with the control group (p<0.01).
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최경해,이부경,권혁,진기천,설상영,정정명 인제대학교 1988 仁濟醫學 Vol.9 No.4
저자들은 1981년 1월부터 1988년 6월까지 인제의대 부산백병원 내과에서 위장관계통의 평활근육종 10예를 경험하고 이들에 대한 상세한 임상적 관찰을 실시하여 그 결과를 보고하고자 한다. A clinical study was performed on 10 cases of leiomyosarcoma of the gastrointestinal system admitted to Inje Medical College, Pusan Paik Hospital, from 1981 to 1988, and the following results were obtained. 1) The locations of the leiomyosarcoma were the stomach(3 cases), the duodenum(3 cases) the jejunum(2 cases), the rectum(1 case) and the omentum(1 case), in order of frequency. The age distribution was wide from 12 years to 60 years, the most prevalent age group was fourth decade(4 cases) and the average age was 43 years. The ratio of male to female was 6 : 4, the male being 6 cases and the female 4 cases. 2) The most common symptom was gastrointestinal hemorrhage, 7 cases out of 10, and the duration of illness was variable, from 3 days to 5 years, but was loot closely related to the severity of illness. 3) The incidence of the leiomyosarcoma of the gastrointestinal system as compared with the other malignant tumor in the same period was about 0.9%, the stomach 0.3%, the small intestine 38.5%(the duofenurn 37.5%, the jejunum 40.0%), the rectum 0.8%, and the omentum 33.3%, which was consistent with other monographs. 4) All 10 cases underwent surgical intervention, postoperative chemotherapy was done on 3 cases in which the regimen was VAC(Vincristine, Adriamycin, Cyclophosphamide) and postoperative radiotherapy was done on 1 case. In brief, the leiomyosarcoma of the gastrointestinal system was most frequent in the small intestine, gastrointestinal hemorrhage the commonest clinical symptom, the duration of the illness was mainly less than 1 year, involved any age group and the overall incidence was less then 1% of the gastrointestinal malignancy.
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