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채식자와 비채식자에서 혈청 지질, 지단백 및 총 항산화능의 비교
김수길(Su Gil Kim),김현일(Hyun Il Kim),엄민섭(Min Sup Yum),조호(Ho Jo),오용열(Yong Yeol O),권한진(Han Jin Kwan),조욱현(Wook Hyun Cho),박정식(Jeong Sik Park) 대한내과학회 2000 대한내과학회지 Vol.58 No.2
N/A Background : Previous studies have demonstrated that modified or oxidized lipoproteins play a key role in the process of atherogenesis, particularly in hyperlipidemic individuals. Low density lipoprotein(LDL) is modified by oxygen free radical from damaged tissue or inflammatory cells. Further changes in the LDL molecule lead to an oxidized form (oxidized LDL), which is recognized by the macrophage scavenger receptor. Scavenger receptors on macrophages recognize and bind oxidized LDL. As uptake continues, the macrophages change to lipid-laden foam cells, the components of the fatty streak, which is the precursor atherosclerotic lesion. Antioxidants are known to prevent modification of LDL by free radicals and possibly also atheroma formation. This study was designed to compare the total antioxidant status and other lipid profiles in vegetarian and non-vegetarian groups in Korean adults to see the effect of diet modification on antioxidant status. Methods : 174 vegetarian and 150 non-vegetarian male adults were recruited for lipid test including total cholesterol, triglycerides, HDL-cholesterol, LDL-cholesterol, lipoprotein(a), and total antioxidant status during annual routine physical examination. Result : 1) Total antioxidant status was significantly high in vegetarian group(1.390±0.288 mmol/L) compared to non-vegetarian group(1.155±0.290 mmol/L)(p<0.001). 2) In non-vegetarian group, total antioxidant status was significantly low in smokers(1.041±0.288 mmol/L) compared to non-smokers(1.227±0.328 mmol/L)(p<0.001). 3) Correaltions between lipid profiles and total antioxidant status in vegetarian and combined groups were not significant. Conclusion : Total antioxidant status in vegetarian group was significantly higher compared to non-vegetarian group. Among non-vegetarian group, smoker group showed lower total antioxidant status compared to non-smoker group. And there was no significant correlations between lipid profiles and total antioxidant status.(Korean J Med 58:197-203, 2000)
성만영,정세진,김종열,조호열,이현석 고려대학교 공학기술연구소 1993 고려대학교 생산기술연구소 생기연논문집 Vol.29 No.1
The Current-Voltage characteristics of LIGBT is verified by SPICE simulation which includes design parameters and process parameters. Important parameter is lateral current gain(h_(fe)) of pup bipolar which consists of p-body, n^- layer and p^+ anode. This current gain is obtained from Ebers-Moll equation. On-resistance of LIGBT consists of channel resistance(R_E) and effective bulk-resistance(R2) which depend on biased gate voltage(V_G). Analysis and modeling of on-resistance are developed from physical structure(geometry and doping profiles) so that it is used in optimizing a design condition of devices.