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요추기능제한을 동반한 입원 환자들에게 있어서 견인보행운동요법을 포함한 통합한의치료의 유효성: 후향적 의무기록 분석
강병구 ( Byeong-gu Gang ),전세환 ( Se Hwan Jeon ),조용규 ( Yongkyu Cho ),이근재 ( Keunjae Lee ),윤영석 ( Youngsuk Yoon ),김종호 ( Jongho Kim ),이원준 ( Won Jun Lee ),한수빈 ( Subin Han ),금창준 ( Chang Jun Kum ),고원일 ( Wonil Koh 한방재활의학과학회 2018 한방재활의학과학회지 Vol.28 No.4
Objectives Low back disability, along with low back pain, places a significant social burden in terms of work loss and medical expenses. Motion-Style-Acupuncture-Treatment using Traction (T-MSAT) is employed as one of the conservative treatments to such conditions. In the present study, effectiveness of Korean Medical treatments, including T-MSAT, was investigated in inpatients with low back disability and low back pain. Methods Among the patients who were admitted between January 2018 to June 2018 with disabled low back function, ones that were treated with T-MSAT were identified. Pain and function were compared at the point of admission and discharge, using Numerical Rating Scale (NRS) and Oswestry Disability Index (ODI), respectively. Results Over the hospitalization period of 34.55 days, pain intensity significantly decreased from NRS score of 6.14 to 3.26 and low back function also significantly improved from ODI score of 50.93 to 33.73 upon receiving Korean Medical treatments including T-MSAT. Conclusions Korean Medical treatments including T-MSAT were found to be effective in inpatients with low back disability with a statistical significance. To evaluate the sole effectiveness of T-MSAT, rigorous clinical trials are necessitated in future. (J Korean Med Rehabil 2018;28(4):51-57)
염수초 포제법에 따른 두충의 항산화 및 항염증 활성 변화 비교연구
고원일 ( Wonil Koh ),이진호 ( Jinho Lee ),하인혁 ( In-hyuk Ha ),정화진 ( Hwa-jin Chung ),이인희 ( In-hee Lee ),이재웅 ( Jae-woong Lee ),김은지 ( Eun Jee Kim ),강병구 ( Byeong-gu Gang ),전세환 ( Se Hwan Jeon ),조용규 ( Yongkyu Cho 대한한의학회 한방재활의학과학회 2017 한방재활의학과학회지 Vol.27 No.2
Objectives The present study aimed to investigate the change in marker compounds, anti-oxidative and anti-inflammatory effects of salt-water processed Cortex Eucommiae. Methods To evaluate the influence of processing on anti-oxidant effect of Cortex Eucommiae, changes in total phenol, total flavonoid, 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging, 2,2`-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) free radical scavenging, and ferric reducing antioxidant power (FRAP) between processed and raw Cortex Eucommiae were assessed. In addition, nitrite assay was conducted to determine the influence of processing on anti-inflammatory effect of Cortex Eucommiae. Cell viability was also examined as to elucidate whether processing affects cytotoxicity of Cortex Eucommiae. Finally, high-performance liquid chromatography (HPLC) analysis was conducted to monitor changes in pinoresinol diglucoside amount of processed and raw Cortex Eucommiae. Results Salt-water processed Cortex Eucommiae showed higher total phenol and flavonoid amount, compared to raw Cortex Eucommiae. Furthermore, anti-oxidative activity of processed Cortex Eucommiae was improved as discovered in DPPH, ABTS, and FRAP assays. Anti-inflammatory effect of Cortex Eucommiae was also enhanced following salt-water processing, as evidenced in nitrite assay. HPLC analysis found that the amount of pinoresinol diglucoside, widely known as the marker compound of Cortex Eucommiae, increases through salt-water processing. All experiments were performed with non-toxic concentration of Cortex Eucommiae; processing did not affect the cytotoxicity of Cortex Eucommiae up to the currently adopted concentration. Conclusions The present results support that salt-water processing of Cortex Eucommiae is beneficial in terms of marker compound amount, anti-oxidative, and anti-inflammatory activities. Additional investigations are needed to standardize the processing method of Cortex Eucommiae. (J Korean Med Rehabil 2017;27(2):29-38)