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강지현 ( Ji Hyun Kang ),이지현 ( Ji Hyun Lee ),조경임 ( Kyoung Im Cho ),김태익 ( Tae Ik Kim ),권혁용 ( Hyuk Yong Kwon ),김현진 ( Hyeon Jin Kim ),김명준 ( Myoung Joon Kim ),황치성 ( Chi Sung Hwang ) 대한류마티스학회 2009 대한류마티스학회지 Vol.16 No.3
Background: Aberrations of cardiovascular regulation have been reported in patients who suffer with fibromyalgia (FM). Abnormalities of the cardiovascular autonomic regulation, as well as the correlation between coronary heart disease and depression, have been considered to be the causative factors. The clinical features of transient left apical ballooning syndrome with the patients under acute stress have been clearly described, but the effect of chronic stress such as FM on the myocardium is unknown. We investigated the cardiac strain in FM patients by strain imaging with using the 2D grayscale images, and we quantified the regional myocardial deformation properties. Methods: We investigated 30 consecutive postmenopausal women (mean age: 48±8 years) who satisfied the criteria for fibromyalgia with atypical chest pain by performing standard and 2-dimensional strain echocardiography (2DS). Those patients with hypertension, coronary heart disease or diabetes were excluded. The global and segmental longitudinal deformation parameters of the LV from 3 apical views were analyzed, and the patients underwent a manual tender point survey for determining the number of tender points and tender point counts, and the patients completed the fibromyalgia impact questionnaire (FIQ), the brief fatigue inventory (BFI), and Beck depression inventory (BDI). Results: The global longitudinal LV strain was significantly reduced in the FM patients with a high FIQ score (>40) as compared to the patients with a low FIQ score (-18.61%vs.-22.72%). Also, both the global and segmental longitudinal LV strains were negatively associated with fatigue or the tender point counts. However, there was no significant association between depression and the LV strain. Conclusion: This study showed the reduced myocardial longitudinal deformation in FM patients. This suggested that strain imaging is a feasible approach to assess the regional ventricular function in FM patients.
증례 : 심근교 환자에서 관상동맥 중재술 후 이면성 긴장의 변화를 보인 1예
김석훈 ( Seok Hoon Kim ),박정호 ( Jeong Ho Park ),안정명 ( Jeong Myung Ahn ),김산 ( San Kim ),이정남 ( Jeong Nam Lee ),조경임 ( Kyoung Im Cho ),김태익 ( Tae Ik Kim ) 대한내과학회 2006 대한내과학회지 Vol.71 No.6
급성 심근경색증과 같은 심각한 경우를 제외하면 심근교 환자에서 스텐트를 이용한 관상동맥 중재술은 흔한 알은 아니다. 특히 심근교 환자에서 관상동맥 중재술 전후에 심초음파를 이용한 이면성 긴장을 측정하여 그 변화를 관찰한 보고는 없었다. 이에 저자들은 베타 차단제와 칼슘 길항제 등의 약물 치료에도 빈번한 협심증 증상을 호소한 중증의 심근교 환자에서 관상동맥 중재술 전 감소되어 있던 이면성 긴장의 횡 이동 정도와 방사형 긴장이 관상동맥 중재술 후 정상적인 양상으로 회복되는 변화를 관찰하였기에 문헌고찰과 함께 국내에서는 최초로 보고하는 바이다. The myocardial bridge of the coronary arteries is observed by coronary angiography at a rate of <5% and ordinarily dues not constitute a hazard. Occasionally, the compression of a coronary artery by a myocardial bridge can be associated with the clinical manifestations of myocardial ischemia during strenuous physical activity and might even result in a myocardial infarction or initiate malignant ventricular arrhythmias. A few cases of percutaneous coronary intervention for a myocardial bridge have been reported. However, there are few reports of the changes in the 2-dirnensional strain in the myocardial bridge. We encountered a case of a myocardial bridge in a 48-year-old male patient who had refractory angina despite continuous medication with a beta-blocker and calcium channel blocker. The 2-dimensional strain of the patient changed after percutaneous coronary intervention with stents. We report the first case in Korea with a review of the relevant literature. (Korean J Med 71:673-677, 2006)
동시증착에 의한 Si(111) - 7×7 기판 위에 TiSi₂ 에피택셜 성장
최치규(Chi Kyu Choi),류재연(Jai Yon Ryu),오상식(Sang Shik Oh),염병렬(Byung Ryul Ryum),박형호(Hyung Ho Park),조경의(Kyoung Ik Cho),이정용(Jeong Yong Lee),김건호(Kun Ho Kim) 한국진공학회(ASCT) 1994 Applied Science and Convergence Technology Vol.3 No.4
초고진공에서 기판 Si(111)-7×7 위에 Ti : Si = 1 : 1 또는 1:2 의 조성비로 Ti와 Si을 동시 증착한 후 in situ 열처리하여 TiSi₂ 박막을 에피택셜 성장시켰다. XRD와 XPS 분석결과 동시증착된 혼합 층에서 C49-TiSi₂ 박막의 성장은 핵형성에 의함을 확인하였으며, 양질의 C49-TiSi₂ 박막은 Ti를 증착한 후 Ti와 Si를 동시 증착한 (Ti+2Si)/(Ti)/Si(111)-7×7 구조의 시료를 초고진공에서 500℃에서 열처리하여 얻을 수 있었다. 형성된 C49-TiSi₂/Si(111)의 계면은 깨끝하였고, HRTEM 분석 결과 C49-TiSi₂/Si(111)의 계면은 약 10℃의 편의를 가지면서 TiSi₂[211]││Si[110], TiSi₂(031)││Si(111)의 정합성을 가졌으며, 시료의 전 영역에 에피택셜 성장되었다. TiSi₂ film was grown epitaxially on the Si(111) substrate by means of the coevaporation of Ti and Si (Ti : Si= 1 : 1 to 1 : 2) on Si(111)-7×7 surface followed by in situ annealing in ultrahigh vacuum. X-ray diffraction and X-ray photoelectron spectroscopy showed that silicide formation was initiated by the nucleation of C49-TiSi₂ crystallites in the deposited layer. High-quality epitaxial C49-TiSi₂ layer was obtained by in situ annealing (Ti+2Si)/Ti/Si(111)-7×7 sample at 500℃ for 10 min in UHV. TiSi₂/Si(111) interface was clear and the orientation relationship between the C49-TiSi₂ and the Si(111) substrate deduced from the HRTEM lattice image was TiSi₂[211]││Si[110], TiSi₂(031)/Si(111) with a misorientation angle of 10˚. The whole area of the sample was covered with the epitaxial C49 structure.