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에탐부톨에 의한 호산구증가증과 전신성 증상증후군 및 이소니아지드에 의한 자가면역간염의 동시발생
최준혁 ( Joon Hyuk Choi ),허내윤 ( Nae Yun Heo ),박승하 ( Seung Ha Park ),박찬선 ( Chan Sun Park ),조경민 ( Kyeong Min Jo ),김우경 ( Woo Gyeong Kim ),남경한 ( Kyung Han Nam ) 대한소화기학회 2016 대한소화기학회지 Vol.67 No.5
Anti-tuberculosis drugs can produce levels of hepatotoxicity ranging from mild elevation of aminotransferase to severe acute hepatitis. A few cases of drug-induced autoimmune hepatitis or the drug reaction with eosinophilia and systemic symptom (DRESS) syndrome by anti-tuberculosis medications have been reported. However, concomitant occurrence of these two disorders has not been reported. Here, we present a case of severe acute hepatitis with DRESS syndrome and autoimmune hepatitis resulting from primary standard anti-tuberculosis drugs. Both conditions were successfully treated with a systemic steroid regimen. (Korean J Gastroenterol 2016;67:267-271)