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이복희,이수봉,이태형,정현욱,정동철,Lee, Bok-Hee,Lee, Su-Bong,Lee, Tae-Hyung,Jung, Hyun-Uk,Jeong, Dong-Cheol 한국조명전기설비학회 2006 조명·전기설비학회논문지 Vol.20 No.1
본 논문은 임펄스전류에 따른 접지시스템의 과도 특성에 관한 것으로 임펄스 전류를 심매설 봉상 접지전극과 그리드 접지전극에 인가하였을 때 나타나는 과도접지임피던스를 조사하였다. 과도접지임피던스는 인가전류의 상승시간과 접지전극의 크기 및 형태에 강하게 의존하며, 접지전극의 인덕턴스는 짧은 시간 영역에서 접지시스템의 과도 접지임피던스에 크게 영향을 미치는 것으로 나타났다. 또한 심매설 봉상접지전극은 짧은 시간영역에서 과도접지임피던스를 줄이는데 효과적이었다. This paper presents the transient behaviors of grounding system impedance against lightning impulse currents. The dynamic characteristics of the deeply driven ground rod and grounding grid subjected to the impulse current were investigated. The transient ground impedance strongly depends on the configuration and size of grounding electrodes and the shapes of impulse currents, and the inductance of grounding electrodes has a significant affect on the transient ground impedance of grounding system Also, the deeply-driven ground rod was effective to reduce the transient ground impedance in time domain of miceroseconds.
이복희(Bok-Hee Lee),이수봉(Su-Bong Lee),이태형(Tae-Hyung Lee),정현욱(Hyun-Uk Jung),정동철(Dong-Cheol Jeong),길형준(Hyoung-Jun Gil) 한국조명·전기설비학회 2005 한국조명·전기설비학회 학술대회논문집 Vol.2005 No.5월
This paper presents the transient behaviors of grounding system impedance against lightning impulse currents. The dynamic characteristics of the deeply driven ground rod and grounding grid subjected to the impulse current with various rise time were investigated. It was found that the transient ground impedance strongly depends on the configuration and size of grounding electrodes and the shapes of impulse currents, and the inductance of grounding electrodes has a significant affect on the transient ground impedance of grounding system in the short time domain.
마가목 및 현지초 추출물의 골손실 및 연골손상 억제효과
문은정(Moon, Eun-Jung),윤유석(Youn, You-Suk),최보윤(Choi, Bo-Yun),정현욱(Jeong, Hyun-Uk),박지호(Park, Ji-Ho),오명숙(Oh, Myung-Sook),소윤조(Soh, Yun-Jo),김선여(Kim, Sun-Yeou) 한국산학기술학회 2010 한국산학기술학회논문지 Vol.11 No.9
본 연구에서는 마가목 (SC), 현지초 추출물 (GT) 및 이들의 1:1 혼합물 시료 (MIX)가 골손실 및 연골손상 억제에 효과가 있는지 알아보기 위해, 각각의 시료를 조골세포주인 MG-63 세포, 파골세포로의 분화를 유도한 Raw264.7 세포와 연골세포로의 분화를 유도한 ATDC5 세포에 처리하여 세포분화 조절 정도를 확인하였다. 각 세포 의 분화 정도는 alkaline phosphatase (ALP) 활성 측정, tartrate-resistant acid phosphatase (TRAP) 염색법 및 alcian-blue 염색법으로 확인하였다. 이들 시료는 MG-63 세포에서 ALP 활성에는 영향을 미치지 않았으나, 마가목 추 출물 (SC) 및 마가목과 현지초 추출물의 혼합시료 (MIX)는 농도 의존적으로 파골세포의 분화를 억제하고 연골세포 의 분화를 촉진하는 것으로 나타났다. 이상의 결과를 종합하여 볼 때, 마가목과 현지초는 골손실과 연골 손상으로부 터 보호할 수 있는 중요한 천연물 소재임을 확인할 수 있었다. 나아가 이들 추출물의 작용기전 및 활성물질 구명에 대한 연구는 추후 더 진행되어야 할 것이다. This study was carried out to investigate the effect of Sorbus commixta (SC), Geranium thunbergii (GT) and their mixture (SC:GT=1:1, MIX) on inhibition of bone loss and chondral defect. To examine their activities, we measured the alkaline phosphatase (ALP) activity in human osteoblast-like MG-63 cells and performed tartrate-resistant acid phosphate (TRAP) staining in osteoclast differentiated from Raw264.7 cells. To investigate the influence on chondrocyte differentiation, we performed alcian-blue staining in chondrocyte differentiated from ATDC5 cells. All of SC, GT and MIX did not increase ALP activity in MG-63 cells. However, SC and mixture (SC:GT=1:1, MIX) significantly inhibited osteoclastic differentiation. And they also induced chondrocyte differentiation. These results suggest that SC and GT may have a potential for the treatment of bone loss and chondral defect by suppression of osteoclast differentiation and stimulation of chondrocyte differentiation. Therefore, clarification of their mechanisms and active components will be needed.
현지초(玄之草)의 진통(鎭痛) 및 항염증(抗炎症) 효과
오명숙 ( Myung Sook Oh ),주미선 ( Mi Sun Ju ),정현욱 ( Hyun Uk Jeong ),김효근 ( Hyo Geun Kim ),박건혁 ( Gun Hyuk Park ),윤유석 ( You Suk Youn ),김영옥 ( Young Ock Kim ),김선여 ( Sun Yeou Kim ) 대한본초학회 2010 大韓本草學會誌 Vol.25 No.3
Objectives: The present study investigated the anti-nociceptive and anti-inflammatory properties of the water extract of Geranii Herba (The stem and leaves of Geranium thunbergii Sieb. et Zucc.) in the animal models of pain and inflammation. Methods: We evaluated the anti-nociceptive and anti-inflammatory activities of Geranii Herba extract (GHE) using the writhing test, tail-flick test, carrageenan-induced paw edema and xylene-induced ear edema models. Two dose of GHE (100 and 1000mg/kg) was administrated orally to the mice. Control group received normal saline and ibuprofen (50mg/kg) was used as a positive control drug. Results: GHE 1000mg/kg treated group showed an increased tail-flick response time in the tail-flick test and inhibitory effect on writhing syndrome induced by acetic acid. Treatment with GHE at the same dose inhibited ear edema induced by xylene and foot edema induced by carrageenan toxicity. Conclusion: The results demonstrate that GHE has anti-nociceptive and anti-inflammatory effects in the various models of nociception and inflammation.