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에어 매트리스와 산소 포화도 측정기를 이용한 수면호흡장애 자동 검출 시스템 개발
정필수,박종욱,주은연,이경중,Jeong, Pil-Soo,Park, Jong-Uk,Joo, Eun-Youn,Lee, Kyoung-Joung 대한의용생체공학회 2017 의공학회지 Vol.38 No.4
The present study proposes a system that can detect sleep-disordered breathing automatically using an air mattress and oxygen saturation. A thin air mattress was fabricated to reduce discomfort during sleep, and respiration signals were acquired. The system was configured to be synchronized with a polysomnography to receive signals simultaneously with other bio-signals. The present study has been conducted with nine adult male and female patients with sleep-disordered breathing, and sleep-disordered breathing events have been detected by applying the signals acquired from the subjects to the rule-based detection algorithm. The sensitivity and positive predictive values were found to evaluate the performance of the system, which are 91.4% and 89.7% for all events, respectively. The comparison of apnea hypopnea index(AHI) between the polysomnography and the proposed method showed squared R-value of 0.9. This study presents the possibility of detecting sleep-disordered breathing at hospitals or homes using the proposed system.
정필수(Pil Soo Jeong) 퇴계학부산연구원 2008 퇴계학논총 Vol.14 No.-
This research interpreted "Chungsanga" which is one of "12 songs of Dosan(陶山十二曲)" by the Korean cogitation system.Firstly, "Chungsanga" is interpreted in respect of Yin-Yang(陰陽). In "green mountain" and "flowing water", mountain is Yang(陽) and water is Yin(陰), and Yin and Yang are in opposing relationship. Mountains are always green and water flows constantly. "We" in the last line of "Chungsanga" can be interpreted that we should exist harmoniously even though we are in opposing relationship like mountains and water. And "Chungsanga" is interpreted in respect of "Five Elements(五行)". Green mountain is "To(土)" and "flowing water" is "Soo(水)". The relationship between "To" and "Soo" in the concept of Five Elements is "ToKukSoo(土剋水). A green mountain is green because of trees and trees are green because of live earth. Live earth means that the earth contains water. To and Soo in opposing relationship but they exist harmoniously and make trees grow. "We" in the last line can be interpreted that we should exist and develop harmoniously. "Chungsanga" is interpreted by concept of the Book of Change(周易). "Green mountain" and "flowing water" are "SanSooMongKwae(山水蒙卦)" among 64 Kwae(卦) of the Book of Change. The meaning of the "SanSooMongKwae" is that we should set a goal and achieve the goal through brave and correct attitude like water flows and flows to reach the ocean overcoming difficulties. Toigye wrote "Chungsanga" after realizing the truth of life taught in the "SanSooMongKwae" in the Book of Change to practice the truth. If interpreted by concept of the Book of Change and Yin-Yang and Ffive Elements, the meaning of "Chungsanga" is that green mountains and flowing water exist and develop harmoniously even though they are in opposing relationship and we humans should learn the truth from nature. This methodology is suggested as a method of appreciation and interpretation of literary works in a creative manner.
정필수 ( Pil Soo Jeong ),박수진 ( Su Jin Park ),김은미 ( Eun Mi Kim ),박지영 ( Ji Young Park ),박유리 ( Yu Ri Park ),강대영 ( Dae Young Kang ),차현욱 ( Hyun Ouk Cha ),이경기 ( Kyoung Ki Lee ),김성희 ( Seong Hee Kim ),박최규 ( Choi 한국가축위생학회 2016 韓國家畜衛生學會誌 Vol.39 No.2
In the study, we developed and evaluated a uracil N-glycosylase (UNG)-supplemented single-tube nested reverse transcription-polymerase chain reaction (UsnRT-PCR) assay that can carried out first-round RT-PCR and second-round nested PCR in a reaction tube without reaction tube opening and can simultaneously detect EU- and NA-PRRSV. The UsnRT-PCR confirmed to have a preventing ability of mis-amplification by contamination of pre-amplified PRRSV DNA from previous UsnRT-PCR. Primer specificities were evaluated with RNAs extracted from 8 viral strains and our results revealed that the primers had a high specificity for both genotypes of PRRSV. The sensitivity of the UsnRT-PCR was 0.1 TCID50/0.1 mL for EU- or NA-PRRSV, respectively, which is comparable to that of previously reported real time RT-PCR (RRT-PCR). Clinical evaluation on 110 field samples (60 sera and 50 lung tissues) by the UsnRT-PCR and the RRT-PCR showed that detection rates of the UsnRT-PCR was 70% (77/110), and was relatively higher than that of the RRT-PCR (69.1%, 76/110). The percent positive or negative agreement of the UsnRT-PCR compared to RRT-PCR was 96.1% (73/76) or 90.9% (30/33), showing that the test results of both assays may be different for some clinical samples. Therefore, it is recommend that diagnostic laboratory workers use the two diagnostic assays for the correct diagnosis for the relevant samples in the swine disease diagnostic laboratories. In conclusion, the UsnRT-PCR assay can be applied for the rapid, and reliable diagnosis of PRRSV without concerns about preamplified DNA carryover contamination that can occurred in PCR process in the swine disease diagnostic laboratories.
압전센서를 이용한 코골이와 심박 검출을 위한 자동 알고리즘
에르덴바야르,박종욱,정필수,이경중,Urtnasan, Erdenebayar,Park, Jong-Uk,Jeong, Pil-Soo,Lee, Kyoung-Joung 대한의용생체공학회 2015 의공학회지 Vol.36 No.5
In this paper, we proposed a novel method for automatic detection for snoring and heart beat using a single piezoelectric sensor. For this study multi-rate signal processing technique was applied to detect snoring and heart beat from the single source signal. The sound event duration and intensity features were used to snore detection and heart beat was found by autocorrelation. The performance of the proposed method was evaluated on clinical database, which is the nocturnal piezoelectric snoring data of 30 patients that suffered obstructive sleep apnea. The method achieved sensitivity of 88.6%, specificity of 96.1% with accuracy of 95.6% for snoring and sensitivity of 94.1% and positive predictive value of 87.6% for heart beat, respectively. These results suggest that the proposed method can be a useful tool in sleep monitoring and sleep disordered breathing diagnosis.