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정정숙 ( Jung Suk Jung ),신승미 ( Seung Mee Shin ),김애정 ( Ae Jung Kim ) 한국식품영양학회 2010 韓國食品營養學會誌 Vol.23 No.2
Sulgidduk samples containing 1, 2, and 4% Adenophora rernotifora powder and a control were examined for moisture content, gelatinization property, color, textural characteristics, and sensory qualities to determine the optimal ratio of Adenophora remotiflora powder in the formulation. The highest viscosity, lowest viscosity, final viscosity, setback and breakdown decreased as the contents of Adenophora remotiflora powder increased in the gelatinization property of flour blends of rice cake made with Adenophora remotiflora powder. The water content of rice cake with Adenophora remotflora powder was 40.54-41.30% and there was no significant difference between samples with Adenophora remotiflora powder. L values indicating brightness were highest in the control group and all of the a values displayed green color indicating that they were negative. The b values were lowest in the control group and the values increased as the level of Adenophora remotiflora powder increased. Evaluation of the mechanical charcteristics of rice cake with Adenophora rernotiflora powder, hardness, cohesion, adhesion and chewiness were all higher in the control group and as its contents were rich, such properties were reduced. In addition, there was no significant difference between adhesion and chewiness. Adhesion and elasticity were low in the control group and as its contents were rich, such properties increased. The results of the sensory test revealed that the, control group containing 1% Adenophora remotiflora powder had the highest color, flavor, taste and overall preference.
Resveratrol Induces Cell Death through ROS-dependent MAPK Activation in A172 Human Glioma Cells
Jung Suk Jung(정정숙),Jae Suk Woo(우재석) 한국생명과학회 2016 생명과학회지 Vol.26 No.2
다형성 신경교모세포종은 사람의 원발성 뇌종양 중 가장 흔하면서 악성이 높은 종양의 하나로 수술과 방사선 치료, 화학치료 등 집중적 치료에도 불구하고 사망률이 높은 종양이다. 레스베라트롤은 다양한 자연산 물질에 포함되어 있는 폴리페놀의 일종으로 여러 종류의 암세포들에서 항암 작용이 있음이 보고되어 있으나 그 기전은 명확하게 밝혀져 있지 않다. 본 연구에서는 사람의 신경교모세포종 기원 세포인 A172 세포에서 레스베라트롤에 의한 세포 사멸 효과와 그 기전을 확인하고자 하였다. 레스베라트롤은 A172세포에서 활성산소종의 생성을 촉진하였으며 N-acetylcystein 혹은 catalase 등의 항산화제들을 전처치시 레스베라트롤의 세포 사멸 효과가 차단되었다. 레스베라트롤은 ERK와 p38 kinase, JNK 등의 인산화를 촉진하였으며 이들 인산화 효소의 억제제들을 전처치하면 레스베라트롤의 세포 사멸 효과가 차단되었다. Caspase 억제제를 전처치시 레스베라트롤에 의한 caspase-3의 활성화와 세포 사멸이 차단되었으며, N-acetylcystein을 전처치시 레스베라트롤에 의한 ERK의 활성화와 caspase-3의 활성화가 차단되었다. 이들 결과를 종합하면 레스베라트롤은 A172 세포에서 활성산소종의 생성을 촉진하며 이는 ERK와, p38 kinase, JNK 등의 활성화를 통해 caspase-의존성 기전으로 세포사멸을 유도하는 것으로 사료된다. Glioblastoma multiforme is the most common and most aggressive type of primary brain tumor in humans. Despite intensive treatment, including surgery, radiation, and chemotherapy, most patients die of the disease. Although the anti-cancer activity of resveratrol has been demonstrated in various cancer cell types, its underlying mechanism in glioma cells is not fully elucidated. The present study was undertaken to investigate the effect of resveratrol on cell viability and to determine the molecular mechanism in A172 human glioma cells. Resveratrol caused the generation of reactive oxygen species (ROS), and resveratrol-induced cell death was prevented by antioxidants (N-acetylcysteine and catalase), suggesting that an oxidative mechanism is responsible for resveratrol-induced cell death. Resveratrol-induced phosphorylation of extracellular signal-regulated kinase (ERK), p38 kinase, and c-Jun N-terminal kinase (JNK), and resveratrol-induced cell death were prevented by inhibitors of these kinases. Resveratrol-induced activation of caspase-3 and cell death were prevented by the caspase inhibitors. ERK activation and caspase-3 activation induced by resveratrol was blocked by N-acetylcysteine. Taken together, these results suggest that resveratrol causes a caspase-dependent cell death via activation of ERK, p38, and JNK, mediated by ROS generation, in human glioma cells.
한국 소방방수피복의 착용만족도 및 개선방안에 관한 조사연구
정정숙(Jung Sook Chung),이연숙(Youn Soon Lee) 대한가정학회 1999 Human Ecology Research(HER) Vol.37 No.12
This study analyzed firefighter's actual wearing condition of tumout gear. The results are as follows: 1. When a firefighter is employed, Korea applies only the minimum of firefighters stature and weight but America applies both the minimum and the maximu
관광브로슈어의 언어적·시각적 메시지 요소가 관광태도 변화에 미치는 영향
정정숙(Chung Jung Sook) 대한관광경영학회 2017 觀光硏究 Vol.32 No.2
본 연구는 관광브로슈어의 커뮤니케이션 효과와 관광브로슈어의 언어적·시각적 메시지요소가 관광태도 변화에 미치는 영향을 알아보는 것이다. 본 연구를 위하여 문헌연구와 실험설계가 병행되었으며 실험설계는 사전 사후 설계를 사용하였다. 본 연구의 실험대상은 안동시 관광브로슈어이며, 피실험자는 200명의 대학생이었다. 주요 연구 결과는 다음과 같다. 관광브로슈어의 노출은 긍정적인 커뮤니케이션 효과가 있었다. 관광브로슈어의 언어적·시각적 요소는 모두 관광태도(인지적, 감정적, 행동적) 변화에 긍정적인 영향을 미치는 것으로 나타났다. 또한 언어적 요소와 시각적 요소의 관광태도변화에는 차이가 있었으며, 언어적 요소에 대해 더 높은 긍정적인 관광태도를 형성하는 것으로 밝혀졌다. This study is to examine the communication effects of tourism brochure and the impacts of verbal and visual components of travel brochure on tourists attitude change. A combination of secondary research and experimental design used for this study. A pretest-post test design was employed. Object of this study was travel brochures of Andong and the subjects were 200 university students. The highlights of the results are as follows: The exposure to the tourism brochure positively influenced the respondents attitude toward the travel destination. The components verbal and visual component per se positively influenced tourists attitude(cognitive, affective, behavioral) change of travel brochure. Also attitude change toward verbal and visual components was found different and the respondents showed more positive attitude toward verbal component.