우분의 병리소견과 진단적가치

정우익,Chung Un Ik 대한수의사회 1977 대한수의사회지 Vol.13 No.4

코로나 이후의 동북아 정세와 원칙 있는 남북관계 로드맵

정우익,김용근 한국문화융합학회 2022 문화와 융합 Vol.44 No.5

After Corona 19, the situation in Northeast Asia has changed rapidly, causing many questions to be raised by experts in all fields, including politics, diplomacy, and society. South Korea is trying to change the way it relies heavily on the US and China by devising an effective strategy in line with the rapidly changing situation in Northeast Asia. In preparation for a further escalation of the US-China conflict, the New Southern Policy and the New Northern Policy are promoting the diversification of countries for diplomatic and economic cooperation, thereby enhancing Korea’s status in the world. In addition, it is necessary to study and promote strategies for improving inter-Korean relations, a long-cherished dream in accordance with the circumstances of the times. The basis of that strategy should be denuclearization and peace negotiations, inter- Korean economic cooperation, and regional peace and economic cooperation.

학교통일교육의 과제와 방향

정우익,김용근 한국문화융합학회 2023 문화와 융합 Vol.45 No.11

This study aims to explore the current reality of unification education and find out how to move toward proper unification education in order to find effective ways to increase the awareness of unification, especially among the younger generation. To achieve the goal of the study, the necessity of unification and unification education was investigated from a legal perspective, and the results of the unification consciousness survey targeting the whole nation and the school unification education survey targeting students were compared and analyzed. Through this, the tasks and directions of school unification education were presented. In order for unification education to stand right, the government (Ministry of Education), teachers, and students must all make efforts. The government shall secure class hours for unification education so that unification education can be carried out smoothly in schools, and shall operate training and workshops so that professional and new unification education methods can be carried out. In addition, teachers and students will have to feel that unification is a survival situation facing us and engage in learning.

실험적 위궤양 발생에 대한 뇌실내 Calcitonin의 영향

정우익,현재헌,고차만 연세대학교 원주의과대학 1989 원주의대논문집 Vol.2 No.1

제 1 회 국무총리 , 교육부장관상 ; 전국 초 , 중 , 고 , 대학생 한자교육 진흥을 위한 글 현상공모 수상작 ; 은상 (수상시 ) - 작은 글자 속에 큰 뜻이

정우익 전국한자교육추진총연합회 2001 한글한자문화 Vol.19 No.-

완전 절제된 제IIIA기 비소세포폐암에서 Cyclin D1, p53, Bcl-2 단백질 발현의 의의

정경영,양우익 대한흉부심장혈관외과학회 1998 Journal of Chest Surgery (J Chest Surg) Vol.31 No.12

연구목적: 폐암은 protooncogene의 활성화와 종양억제유전인자(tumor suppressor gene)의 비활성화 등 다단 과정에 의하여 발생한다. 치료목적의 완전 절제가 가능하였던 제 IIIA기 비소세포폐암 환자에서 cyclin D1, p53, bcl-2 gene의 변이가 폐암에 미치는 영향을 조사하고자 하였다. 대상 및 방법: 1990년부터 1995년까지 연세의료원에서 치료목적의 완전절제가 가능하였던 stageIIIA 비소세포폐암 환자 100명의 paraffin block과 임상기록을 이용하였다. 각 환자의 조직절편을 labelled streptavidin-biotin method로 immunohistochemical 염색하였고 cyclin D1, p53, Bcl-2 immunostaining을 위한 조직절편들은 immunostaining하기 전 citrate buffer 내에서 10분에서 20분간 microwave oven으로 전처치한 후 cyclin D1은 NCL-cyclin D1-GM으로 p53는 lone DO-7으로 bcl-2는 clone 124로 overnight incubation하였다. 수술 후 평균 추적조사기간은 24.1 개월(range; 2∼84 개월)이었다. 결과: 100예의 폐암 중 56예가 편평상피세포암, 37예가 선암, 5예가 adenosquamous cell carcinoma, 2예가 대세포암이었고 수술 후 5년 생존율은 32.1%이었다. cyclin D1의 양성율은 35 %, p53는 56 %, bcl-2는 17 %였으나 cyclin D1, p53, Bcl-2 단백질 양성 발현과 생존율과의 상관관계는 없었다. 결론: 연구결과 cyclin D1, p53, Bcl-2 단백질 양성 발현이 비소세포폐암 발생기전과 연관되어 있으나 수술 후 예후인자로서는 부적당한 것으로 판단되었다. Background: Lung cancer formation is a multistage process involving activation of protooncogene and inactivation of tumor suppressor genes. We evaluate the significance of cyclin D1, p53, bcl-2 gene mutations in patients with curatively resected stage IIIA non-small cell lung cancer(NSCLC). Material and Method: One hundred consecutive cases of stage IIIA lung cancers from patients operated on curatvely between 1990 and 1995 for which adequate paraffin blocks and clinical history were available. Immunohistochemical studies were performed on the representative tissue sections from each case by the labelled streptovidin- biotin method. Sections for cyclin D1, p53, Bcl-2 immunostaining were pretreated in a microwave oven for 10 to 20 minutes in citrate buffer before immunostaining. The overnight incubation with NCL-cyclin D1-GM for cyclin D1, with clone DO-7 for p53, with clone 124 for bcl-2 was done. Mean follow-up was 24.1 months (range 2-84 months) after operation. Result: One hundred cases of lung cancers were composed of 56 cases of squamous cell carcinoma, 37 cases of adenocarcinoma, 5 cases of adenosquamous cell carcinoma, and 2 cases of large cell carcinoma. The 5-year survival was 32.1%. The positive expression rate of cyclin D1 was 35%, p53 was 56%, and bcl-2 was 17%. But there were no correlation between cyclin D1, p53, Bcl-2 protein expression and survival. Conclusion: These observation indicate that cyclin D1, p53, bcl-2 protein overexpression might be implicated in the oncogenesis of non-small cell lung carcinomas but they have no usefulness as a prognostic marker.

응급실을 내원한 요관결석 환자에서 크기가 5 mm 이상인 집단과 5 mm 미만인 집단 간의 임상적 특성과 neutrophil-lymphocyte ratio, platelet lymphocyte ratio, C-reactive protein의 비교

정원동,최우익,정원호,박동진,서영진,전재천 대한응급의학회 2021 대한응급의학회지 Vol.32 No.5

Objective: The size and location of ureter stones are important factors in their spontaneous passage. We compared the clinical characteristics and neutrophil-lymphocyte ratio (NLR), platelet lymphocyte ratio (PLR), and C-reactive protein (CRP) of patients who visited the emergency department with ureter stones of ≥5 mm and <5 mm in size. Methods: We retrospectively reviewed 699 patients who visited the emergency department of two medical centers from January 2017 to December 2019. We compared microscopic hematuria, pyuria, NLR, PLR, CRP, the grade of hydronephrosis, and the location of ureteral calculi between the two groups. Results: There were 419 patients with ureter stones less than 5 mm and 280 patients with stones more than 5 mm in size. NLR was 2.82 (1.44-4.73) and 3.12 (1.94-5.75) in patients with stones <5 mm and ≥5 mm, respectively (P=0.001). PLR was 117.2 (88.2-164.9) and 136.0 (98.9-199.7) in patients with stones <5 mm and ≥5 mm, respectively (P=0.001). CRP was 0.29 (0.29-0.29) and 0.29 (0.29-1.04) in patients with stones <5 mm and ≥5 mm, respectively (P<0.001). The proportion of microscopic hematuria was 84.7% and 76.4% in patients with stones <5 mm and ≥5 mm, respectively (P=0.006). The proportion of pyuria was 20.5% and 41.8% in patients with stones <5 mm and ≥5 mm, respectively (P=0.01). Conclusion: In patients with ureter stones ≥5 mm, CRP, NLR, and PLR were significantly higher than patients with ureter stones <5 mm. However, further studies are needed before using these indicators to make clinical decisions regarding ureteral stone management.

심장의 원발성 맥관육종 -1예 보고-

조미연,정순회,양우익,최경훈,이종국 대한병리학회 1993 Journal of Pathology and Translational Medicine Vol.27 No.4

回轉翼航空機 修理附屬 最適需要豫測 硏究

崔錫喆,鄭宇益 國防大學校 2000 敎授論叢 Vol.20 No.-

본 연구는 야전에서 항공기 수리부속의 보급 환연으로 인하여 항공기 가동률이 저하되는 것을 해소하기 위한 목적으로 실시하였으며, 육군에서 운용하고 있는 회전익 항공기 중 한 개 기종의 수리부속 중에서 연간 1개 이상 소요되는 주요 수리부속을 대상으로 가장 적합한 수요예측 모형을 도출하기 위한 연구이다. 본 연구에서는 현재 육군항공에서 사용중인 수요예측기법(이동평균법)과 제시하고자 하는 새로운 예측기법인 최소자승법과 적응지수평활법을 동일한 언어로 프로그래밍한 후, 과거의 수리부속 소모실적 데이터를 특성별로 그룹화하여 각각의 설계된 모형에 적용한 결과를 상호 비교함으로써 항공기 수리부속을 예측하기 위한 가장 적합한 수요예측 모형을 제시하고자 하였다. 결과 분석은 각각의 모형을 실행시킨 예측치와 과거의 실적치와의 절대오차를 모형별로 비교하여 정확도를 측정하였으며, 결과적으로 적응지수평활법이 항공기 수리부속의 수요를 예측하는데 가장 적합한 기법임이 수치적으로 입증되었다. 향후 항공기 수리부속의 수요실적에 대한 자료가 지속적으로 관리된다면 보다 과학적이고 정확한 예측기법으로 정착될 것으로 기대된다.

전종격동에 생긴 췌장낭 -1예 보고-

권계원,정경영,양우익 대한병리학회 1998 Journal of Pathology and Translational Medicine Vol.32 No.11