백서에서 유발된 염증에 대한 Triamcinolone Acetonide 이온도입 경피투과 효과

정대인,김태열,김계엽,김명훈,Jung Dae-In,Kim Tae-Youl,Kim Kye-Yoep,Kim Myong-Hoon 대한물리치료학회 2003 대한물리치료학회지 Vol.15 No.2

This study investigated the effects of triamcinolone acetonide by iontophoretic transdermal drug delivery on anti-inflammatory action into the rats and which had carrageenan-induced hyperalgesia and edema in the feet, trauma-induced tissue damage in the thigh. Each group was treated under the fellowing conditions. 1. Group I : Control group 2. Group II : Application of direct current 3. Group III : Application of 0.1$\%$ triamcinolone acetonide solution 4. Group IV : Iontophoresis of 0.1$\%$ triamcinolone acetonide solution The degree of anti-inflammation was evaluated by the paw withdrawal latency, the change in volume of foot the change of paw edema, histological change in rats. 1. In paw withdrawal latency, group IV showed the most significant therapeutic effect than the other groups at 0, 3, 6 and 9 hours(p < 0.001). 2. In paw edema experiment in the foot, group IV showed the most significant effect than group I at 0, 3, 6 and 9 hours. It meant that there was effective anti-inflammatory reaction in group I (p < 0.001). 3. In the light microscopic observation, group IV showed the most significant reduction of haemorrhage, hyperemia and infiltrative inflammation. From the results, the iontophoresis with triamcinolone acetonide is more effective than using each groups. It is one of the effective physical agent which delivered large molecular weight drug into the body. The continuous study is needed for many interesting issues of iontophoretic transdermal drug delivery in new future.

지연성 근육통에 대한 Triamcinolone Acetonide의 이온도입 경피투과

정대인,김명훈,황태연,윤세원,최은영,Jung, Dae-In,Kim, Myong-Hoon,Hwang, Tae-Yeun,Yoon, Se-Won,Choi, Eun-Young 대한임상전기생리학회 2003 대한임상전기생리학회지 Vol.1 No.1

This study investigated the effects of triamcinolone acetonide by iontophoretic transdermal drug delivery on anti-inflammatory action into the human which had excentric exercise-induced delayed onset muscle soreness in the non-dominant arm. The degree of anti-inflammation was evaluated creatine posphokinase(CPK) by serum enzyme activity and subjective pain threshold by soreness muscle scale in clinical study. The results Were as follows; 1. In a subjective pain scale, all groups showed non-significant difference but, showed a tendency to decrease numerical value in human. 2. In the serum CPK level, iontophoresis group showed more significant reduction than other groups at 24, 48 and 72 hours. From the results, the iontophoresis with triamcinolone acetonide is more effective than using each groups. The continuous study is needed for many interesting issues of iontophoretic transdermal drug delivery in new future.

뇌졸중 유병경험자와 정상 노인의 신체활동 강도에 따른 심혈관질환 위험요인 비교

정대인(Dae-In Jung),고대식(Dae-Sik Ko),김현중(Hyun-Joong Kim) 대한심장호흡물리치료학회 2021 대한심장호흡물리치료학회지 Vol.9 No.2

Purpose : This study aimed to analyze the difference in the cardiovascular risk factors between post-stroke elderly patients and healthy elderly patients, according to the intensity of physical activity, to determine the effect of physical activity on stroke-related cardiovascular risk factors. Methods : This study involved 4,956 elderly participants(aged >65 years) out of 24,269 subjects who participated in the 7th National Health and Nutrition Examination Survey(2016–2018). Variables that were risk factors for cardiovascular disease in the selected subjects were analyzed. Results : Total cholesterol was significantly higher in the healthy elderly group compared with the post-stroke elderly group(P < 0.05 ), and fasting blood glucose was significantly higher in the post-stroke elderly group compared with the healthy elderly group(P < 0.05 ). H DL c holesterol w as s ignificantly h igher in t he healthy e lderly group compared w ith the p ost-stroke elderly group(P < 0 .05 ). Conclusion: Comparison of the intensity of physical activity revealed the importance of blood sugar control through regular aerobic exercise and exercise intensity. It is suggested that this can serve as basic data for health promotion in stroke patients and the preventive management of cardiovascular disease in healthy elderly people.

20대와 40대의 급성 및 만성요통환자의 척추주위 근육에 관한 횡단면의 비교

김대훈(Dae-Hun Kim),박진규(Jin-Kyu Park),박윤진(Yun-Jin Park),정대인(Dae-In Jung),김성수(Seong-Su Kim) 한국콘텐츠학회 2011 한국콘텐츠학회논문지 Vol.11 No.6

이 연구는 20대와 40대의 급성과 만성 요통환자를 대상으로 척추 주위근육의 단면도를 비교하는 것이다. 20대(남자-9, 여자-10)와 40대(남자-8, 여자9)의 대상자들은 MRI로 요추(4번 하부 종단판) 단면도의 척추주위근육(장요근, 다열근, 척추기립근)들의 크기를 PACS(free-handling technique of the picture archiving and communication system(PACS)을 이용하여 측정하였다. 연구 결과 20대 급성과 만성 요통환자들의 척추 주위근들의 차이는 통계학적으로 유의성이 없게 나타났으나, 40대 급성과 만성 요통환자들의 척추 주위근들의 차이는 만성 요통환자들이 근 위축이 통계학적으로 유의성 있게 나타났다. 또한 20대와 40대의 만성요통환자 척추 주위근들의 차이도 40대 만성요통 환자들에게 유의성 있게 나타났다. 연구에서 20대 만성환자들의 근 위축은 나타나지 않았으나 40대 만성환자들은 다양한 이유로 근 위축이 나타났다. 따라서 40대의 만성 요통환자들은 조기의 다양한 요부 근력 운동 및 기능적 활동 등으로 허리 주위근육의 위축을 감소시키는 것이 필요하다. The purpose of this study was to compare acute and chronic LBP patient in twenties and forties, respectively by size measure paraspinal muscle (cross-sectional area; CSA). CSA of paraspinal muscle (psoas, multifidus, erector muscle) size was measured by free-handling technique of the picture archiving and communication system(PACS) using MRI at the level(lower end-plate of L4) in twenties(9 males, 10 females) and forties(9 males, 8 females) in acute and chronic LBP patient. The results of this study showed no significantly difference between acute and chronic LBP (p>0.05) in twenties patients. However, there was significant difference between acute and chronic LBP (p<0.05) in forties patients. Also, there was significant difference in paraspinal muscle CSA between chronic LBP patients in twenties and chronic LBP patients in forties (p<0.05). This study showed that paraspinal muscle atrophy was observed in forties with various cause, but Not chronic LBP patients in twenties. Accordingly it is required for chronic LBP patients in forties to minimize trunk muscle atrophy through immediate back muscle dynamic exercise and early functional activity.

뉴노멀 시대의 ‘소수적인 신학’(Minority theology)에 관한 소고 - 질 들뢰즈의 소수성을 중심으로

정대인(Dae-in Jung) 한국기독교학회 2021 한국기독교신학논총 Vol.122 No.-

전지구적 자본주의 문명이 야기한 기후변화와 생태계 파괴는 결국 코로나 바이러스를 통한 팬데믹 사태를 불러왔다. 한국 사회는 이제 팬데믹이라는 부정적인 것과 함께 머물기를 준비해야 하는 시점에서 사회 전반의 표준에 대한 재성찰을 요구하고 있다. 이런 취지에서 본 소고는 제도화된 기독교의 표준을 비판적으로 고찰하며, 기독교의 뉴노멀을 질 들뢰즈(Gilles Deleuze)의 소수성을 중심으로 재구성하고자 한다. 들뢰즈에게 소수성은 표준화/균일화 같이 정해진 영토를 벗어나는 창조와 생성의 탈영토화(deterritorialization)를 의미한다. 본고에서는 기독교의 표준을 추동하는 보편성과 초월성의 신학을 ‘다수적인 신학’(majority theology)으로 규정하며, 이를 ‘소수적인 신학’(minority theology)과 대비시킨다. 소수적인 신학은 제도화된 기독교의 표준을 벗어나는 흐름을 의미하며, 본 소고에서는 1) 감응의 존재론 2) 내재성의 구도를 뉴노멀 시대의 기독교 신학의 새로운 조건으로 제언하고자 한다. Climate change and ecological destruction led by a global capitalist civilization eventually gave rise to the COVID-19 pandemic. At this very moment, Korean society has the need to acknowledge that it must prepare for a “tarrying with the negative” of the pandemic, and as such, is currently pushing for a re-examination of the notion of ‘normal’ in society as a whole. This paper critically reviews the norms of institutionalized Christianity and attempts to organize the New Normal of Christianity centered on the concept of a minority developed by Gilles Deleuze. Deleuze argues that minority means the deterritorialization of creation and formation that go beyond the prescribed territory such as norms/uniformity. This paper prescribes the ideological and transcendental theology that drives this form of norms in Christianity as a ‘majority theology’ and contrasts it with ‘minority theology’. Minority theology can be defined through the flows that deviate from the norms of institutionalized Christianity. The present study suggests 1) an ontology of affect, and 2) the plane of immanence: as the characteristics of minority theology, and proposes these elements as the new conditions for Christian theology in the age of the New Normal.

긴장성 두통이 있는 대학생들에게 시청각적 엔터테인먼트와 연부조직 가동술이 압력통각역치, 바이오피드백, 뇌파에 미치는 영향

정대인(Dae-In Jung),이은상(Eun-Sang Lee),김현중(Hyun-Joong Kim) 한국엔터테인먼트산업학회 2020 한국엔터테인먼트산업학회논문지 Vol.14 No.7

긴장성 두통은 성인들에게 나타나는 두통 중 가장 흔한 일차성 두통이다. 장기간의 두통은 만성 두통을 야기시키고 일상생활에 큰 영향을 미친다. 본 연구의 목적은 긴장성 두통의 병원성 요인과 심인성 요인의 관리에 적합한 시청각적 엔터테인먼트와 연부조직 가동술을 통해 긴장성 두통에 기여하는 바를 비교하고자 한다. 연구대상은 6개월 이상 간헐적 혹은 지속적인 두통을 호소한 자로 선정된 30명에서 시청각적 엔터테인먼트군, 연부조직 가동술군, 시청각적 엔터테인먼트와 연부조직 가동술군 각각 10명씩 배정하였다. 배정된 군에서는 사전검사 후 4주간 주 3회씩 총 12회의 중재를 받고 사후검사를 실시하였다. 평가는 압력통각역치감각과 바이오피드백을 이용한 정신생리학적 변수, 뇌파를 측정하였다. 측정된 결과는 이요인 반복측정 분산분석을 통해 측정 시점에 따른 군간의 교호작용을 분석하였다. 압력통각역치 결과, 오른쪽 등세모근의 결과에서 교호작용이 나타났으며 (p<.05), 시청각적 엔터테인먼트를 통한 중재군에서 가장 큰 증가의 폭을 보였다. 따라서 병원성 요인의 근육에 대한 직접적인 접근이 아닌 심리학적인 요소에 입각한 시청각적 엔터테인먼트를 통해 근육에 대한 통증역치에 긍정적인 영향이 보였지만 통계학적으로 유의하지 않았던 정신생리학적 변수와 뇌파에도 긍정적인 평균값의 변화량이 관찰되었다. 이를 통해 긴장성 두통의 관리에 있어 시청각적인 자극은 고려되어야 한다고 제언한다. TTH(tension-type headache) is the most common primary headache among adults. Long-term headaches cause chronic headaches and have a better impact on daily life. The purpose of this study is to compare the contributions to TTH through AVE(audio-visual entertainment) and STM(soft tissue mobilization) suitable for management of pathogenic and psychogenic factors of TTH. The participants of this study were from 30 people who complained of intermittent or persistent headaches for more than 6 months, and 10 participants each in the AVE group, STM group, and AVE plus STM group. In the assigned group, a total of 12 sessions were performed three times a week for 4 weeks after the baseline, followed by post-test. Outcome measures measured PPTs(pressure pain thresholds), psychophysiological parameters, and EEG(electroencephalogram). The measured results were analyzed for interaction between time and group through a two way rmANOVA(repeated measurement variance analysis). As a result of the PPTs, interaction was found in the results of the right trapezius (p<.05), and the more improvement was observed in the AVE group. Therefore, through AVE based on psychological factors rather than direct access to the muscles of pathogenic factors, a positive impact on the PPTs was shown, but the average value of the psychophysiological parameters and brain waves that were not statistically significant. The amount of change was observed. Through this, it is suggested that audio-visual stimulation could be considered in the management of TTH.

라이프케어테인먼트 기반 50세 이상 한국성인의 무릎관절염 유병률과 관련요인

정대인(Dae-In Jung),박종항(Jong-Hang Park),고대식(Dae-Sik Ko) 한국엔터테인먼트산업학회 2018 한국엔터테인먼트산업학회논문지 Vol.12 No.7

본 연구의 목적은 무릎관절염을 K/L 2등급 이상과 3등급 이상으로 구분하여 유병률의 차이를 알아보고 관련요인을 규명하여 무릎관절염의 예방교육자료 및 보건사업의 기초자료를 제공하기 위해 실시하였다. 국민건강영양조사 제5기 3차년도 자료 중 50세 이상 성인 2,906명을 최종대상자로 선정하였다. 연구결과 한국 50세 이상 성인의 K/L 2등급 이상 무릎관절염의 유병률은 33.4%이었고, 이를 남성과 여성의 유병률로 구분하면 각각 20.1%, 43%이었다. K/L 3등급 이상은 19.9%이었고, 남성은 9.5%, 여성은 27.3%이었다. 무릎관절염은 K/L 2등급 이상에서 성, 연령, 교육정도, 흡연상태, 체질량지수, 무릎관절통 유무, 무릎관절 통증수준과 유의한 상관성이 있었고, K/L 3등급 이상은 성, 연령, 체질량지수, 무릎관절통 유무, 무릎관절 통증수준과 유의한 상관성이 있었다. This study was performed to provide the basic data for healthcare services and educational materials to prevent knee osteoarthritis by identifying different prevalence of Kellgren/Lawrence grade 2 and 3 and their related risk factors. Among the 5th survey in 3rd year Korean National Health and Nutrition Examination Survey data, 2,906 people over 50 years old were selected as final subjects. The result showed that the prevalence of knee osteoarthritis as K/L grade 2 was 33.4% in Koreans over 50 years old and the prevalence in male and female were 20.1% and 43% respectively. The prevalence of K/L grade 3 for knee osteoarthritis was 19.9% and the prevalence in male was 9.5% and in female was 27.3%. For knee osteoarthritis as K/L grade 2, gender, age, educational level, smoking status, body mass index, knee joint pain, and the level of knee pain were significantly correlated and for K/L grade 3, gender, age, body mass index, knee joint pain, and the level of knee pain showed significant correlations.

노인장기요양보험제도 내 가정방문물리치료 도입에 관한 인식도 및 필요성 조사

정대인(Dae-In Jung),김찬규(Chan-Kyu Kim),고대식(Dae-Sik Ko) 한국콘텐츠학회 2014 한국콘텐츠학회논문지 Vol.14 No.6

본 연구는 노인장기요양보험제도에서 가정방문물리치료 제도의 도입과 정착을 위해 수급자 측면의 환자와 공급자 측면의 물리치료사의 인식 및 필요성에 대한 의견을 알아보고자 하였다. 조사 참여자는 광주광역시 소재 의료기관에 근무하는 물리치료사(130명)와 환자(96명)를 대상으로 설문조사를 실시하였다. 연구결과 환자(60.4%)와 물리치료사(75.4%)는 장기요양보험제도에서 간호사 및 간호조무사에 의해 제공되는 신체활동 지원서비스는 전문성이 부족하며, 가정방문물리치료를 통해 질적인 치료가 가능할 것이라고 응답하였다(환자 47.9%,물리치료사 59.2%). 또한 장기요양보험제도 개선 시 가장 우선순위에 대한 질문에서 환자는 급여비 절감(35.4%)과 대상자 확대(32.3%),치료사는 전문인력 확대(73.8%)와 다양한 재활서비스의 도입(20.2%)순으로 응답하였고,재활팀의 도입이 필요하다고 응답하였다. 가정방문물리치료가 필요한 이유는 환자가 의료기관에 가기 힘듦(PT 30.0%)과 노인의 신체기능이 향상(pt47.1%)되기 때문이라고 응답하였다. 결론적으로 물리치료사뿐만 아니라 수요자인 환자 대부분에서 노인장기요양보험제도 내에 가정방문물리치료 도입에 관한 필요성 및 인식도가 현저히 높은 것으로 나타나 제도의 시행이 시급한 것으로 판단된다. This study aims to investigate the awareness and needs of patients as consumers and therapists as providers on the introduction of home physical therapy in the long-term care insurance. The survey participants were 96 patients and 132 physical therapists to a questionnaires, we analyzed for frequency of each questionnaire about awareness and necessity. As a result of the test, they considered that physical activity support services provided by nurse and nurses aid ware not specialized enough(pt60.4%, PT 75.4%) and quality therapy should be available through a home physical therapy(pt47.9%, PT 59.2%). Also, patients responded that the priorities to improve long-term care insurance were given to lowering expenses(35.4%) and expanding coverage of subjects(32.3%) while the physical therapists responded that professionals should be expanded(73.8%) and diverse rehabilitation services(20.2%) and a rehabilitation team should be introduced. They responded that the reasons of home physical therapy were needed that it was hard for patients to visit medical centers(PT 30.0%) themselves and it would be improvable for them to get physical function in elderly(pt47.1%) through the service. In conclusion, as most patients as well as physical therapists responded that home visit therapy services should be introduced and their awareness of it was very high, it is suggested that the service should be quickly introduced as soon as possible.

가상현실 체험형 운동과 요부안정화운동에 따른 뇌졸중환자의 낙상관련 신체․심리적 비교 분석

정대인(Dae-In Jung),서태화(Tae-Hwa Seo),고대식(Dae-Sik Ko) 한국콘텐츠학회 2012 한국콘텐츠학회논문지 Vol.12 No.8

이 연구는 뇌졸중 환자를 대상으로 낙상예방을 위하여 가상현실 체험형 게임 운동(Nintendo-Wii Sport-NWS)과 요부안정화 운동을 실시하고 낙상관련 신체?심리 기능 변화를 측정하였다. 뇌졸중환자 30명을 대상으로 신체적 기능은 정적, 동적균형으로 측정하였고 심리적기능은 낙상효능감을 측정하여 운동 전과 운동 후, 각 운동군간을 비교분석하였다. 정적균형은 BBS, FRT, 동적균형은 TUG, 10m 보행검사, 낙상효능감은 낙상 효능감 지수로 측정되었다. 그 결과 두군 모두 신체?심리적기능에서 유의한 개선을 나타내었다. 그러나 BBS, FRT, 10m보행에서 요부안정화 운동군이 더 통계적으로 개선된 것으로 나타났으며 낙상효능감은 가상현실 체험형 게임 운동 군에서 더욱 개선된 것으로 나타났다. 결론적으로 가상현실 체험형 게임운동은 뇌졸중환자의 신체?심리적 기능 증진에 긍정적인 영향을 미친다. This study conducted the following experiment to examine change of physicopsychological function on lumbar stabilization exercise(LSE) and virtual reality game training(Nintendo Wii Sport-NWS) to stroke patients subject for fall prevention. Psychological function was measured by falls efficacy with stroke patients and physical function was measured by static and dynamic balance on comparative analysis of pre, post exercise and each groups in 30 stroke patient subject. Static balance was measured by BBS, FRT, dynamic were measured by TUG, 10m walking test and falls efficacy with stroke patients was measured index of falls efficacy. These result lead us to the conclusion that each group were statistically improved at all physicopsychological test. but BBS, FRT, 10m walking test were more statistically improved at LSE group and falls efficacy with stroke patients were more improved at virtual reality game training group. Consequently, virtual reality game training would be lead to positive increment of physico sychological function on stroke patient.

음악 템포에 따른 유산소 운동이 스트레스 요소에 미치는 효과

정대인(Dae-In Jung),장일용(Il-Yung Jang),이은상(Eun-Sang Lee) 대한심장호흡물리치료학회 2020 대한심장호흡물리치료학회지 Vol.8 No.1

Purpose : The purpose of this study is to assess changes in the circulatory system according to the tempo of music while performing treadmill exercises. Methods : This study selected a total of 21 healthy students (ten male and eleven female) in the department of physical therapy at Gwangju Health University. Participants exercised for 30 minutes once a week for a total of three weeks. Participants’ heart rate, autonomic nervous system activity, and blood pressure were measured at pre-test and post-test intervals. In the first week, treadmill exercise was completed without music. In the second week, we applied slow tempo music (60~80 bpm) while using the treadmill, and in the third week, we applied fast tempo music (120~140bpm). The measured data were analyzed by repeated-measurements ANOVA using the before and after values for each music tempo. The results are displayed as differences between the three groups. Results : There were no significant differences in heart rate, systolic blood pressure, diastolic blood pressure, or RMSSD (autonomic nervous system) between the three groups. There was a significant difference in LF/HF (autonomic nervous system) between the three groups. Conclusion : According to our results, there was some evidence for music tempo benefiting the autonomic nervous system during exercise. However, there is a need for more study on this subject. Continued research on this subject could provide benefits to the science of physiotherapy as it relates to cardiopulmonary treatment.