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한국성인에서 S상결장경검사로 관찰된 대장 용종의 빈도와 특성

이화영(Hwa Young Lee),김재준(Jae Jun Kim),김영호(Young Ho Kim),성인경(In Kyung Sung),전성국(Seong Gook Jeon),손희정(Hee Jung Son),이풍렬(Poong Lyunl Rhee),고광철(Kwang Chul Koh),백승운(Seung Woon Paik),이종철(Jong Chul Rhee),오영륜(Y 대한내과학회 1998 대한내과학회지 Vol.55 No.1
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N/A Objectives: Colorectal polyps play an integral role in the development of colon cancer. The prevalence of colorectal polyps in Korea was reported to be 5-12%. However, these results were obtained from retrospective studies, in which the subjects were symptomatic patients. Therefore, we performed a prospective study in asymptomatic Korean adults to determine the prevalence, characteristics, and risk factors of colorectal polyps. Methods Flexible sigmoidoscopy was done during the period between August 1994 to November 1995 in 2,985 aymptomatic individuals who visited Samsung Medical Center for health check-ups. Results : 1) Polyps were found in 590 subjects (20.4%) out of 2,985 individuals. The prevalence rate increased with age. 2) In histologic findings of colorectal polyps, there were 369 cases (45.8%) of adenomatous polyps, 245 cases (30.4%) of hyperplastic polyps and 5 cases of carcinomas. 3) Moderate to severe dysplasia was found in 15.4% of adenomatous polyps and the grade of dysplasia increased with polyp size. 4) The prevalence rate of polyps increased according to obesity, blood cholesterol and triglyceride level, the frequency of alcohol consumption and the amount of smoking in cases. Conclusions: Screening by sigmoidoscopy is considered to be beneficial for detection of colorectal polyps in asymptomatic Korean adults, especially in individuals with risk factors such as obesity, heavy smoking and alcohol consumption.
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부식제에 의한 상부 소화관 손상에 대한 내시경적 연속추적검사에 관한 고찰

박충기(Choong Kee Park),김학양(Hak Yang Kim),신호균(Ho Kyun shin),정인구(In Goo Jung),전성국(Sung Gook Jun),유재영(Jae Young Yu) 대한소화기학회 1990 대한소화기학회지 Vol.22 No.2
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The ingestion of caustic agents can initiate a progressive and devastating injury to the esophagus and stomach. Since the introduction of concentrated alkaline cleansers in the 1960s, the incidence of seveve injury has increased. If the patient survives the acute effects of caustic ingestion, the reparative response can result in esophageal and gastric stenosis and an increased incidence of esophageal cancer. There are little reports in the case of the strong acid was ingested, and especially no reports about the periodic gastrofiberscopic examination. We have done the periodic gastrofiberscopic examination every a week for four times to whom ingested the caustic agents. The results obtained were as follows: 1) Male to female ratio was 7:6. The mean age was 33.6 years. (range: 18 to 59) 2) Amount of acid ingested was about 30 to 100 cc. 3) The motive of ingestion was accidental in 2 patients, suicidal attempt in 11 patients, and 4 patients of whom was major depression patients. 4) Patients with ulcer had more severe and many symptoms than patients with gastritis and esophagitis. 5) Of the 13 patients, stricture developed in 5 patients, esophageal stricture in 3 patients, and gastric antral stricture in 2 patients. 6) The esophageal injury was more severe than the gastric injury, probably that is due to ingestion of highly concentrated acid. 7) In 3 patients, serial fiberoptic gastroscopy demonstrated nodular regeneration at 2 weeks after ingesting caustics, esophageal or gastric antral stricture 3 or 4 weeks later. 8) In 5 patients with stricture, 4 patients required operation. Remaining patients without stricture were treated conservatively with antacid or H2 antagonist without subsequent complication.9) None of 13 patients expired. 10) 9 patients had followed-up from 3 months to 15 months after ingestion, 8 patients of whom were free of symptoms, only 1 patient persisted anorexia and dysphagia.

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