http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
전병화(Jeon, Byeong-Hwa),김상섭(Kim, Sahng-Seop),김세훈(Kim, Se-Hoon),장석종(Chang, Seok-Jong) 대한생리학회 1990 대한생리학회지 Vol.24 No.2
The contractile action of barium (Ba<sup>2+</sup>) was investigated in the arterial strip of rabbit renal artery. The helical strip of isolated renal artery was immersed in the Tris-buffered Tyrode s solution equilibrated with 100% O<sup>2</sup> at 37℃ and its isometric tension was measured. Ba<sup>2+</sup>-induced contraction of arterial strip was dose-dependent and its maximal tension corresponded to 92.1±4.5% of tension by K<sup>+</sup>(100 mM). Ba<sup>2+</sup>-induced contraction did not show the tachyphylactic phenomenon in the normal Tyrode s solution. Ba<sup>+2</sup> induced the tonic contraction in the Ca<sup>2+</sup>-free tyrode s solution and that was increased by the extracellula addition of Ca<sup>2+</sup>. During the repeated exposure of the same dose of Ba<sup>2+</sup> (10 mM) in the Ca<sup>2+</sup>-free Tyrode s solution, Ba<sup>2+</sup>-induced contraction was progressively decreased. Even though the intracellular NE-and caffeine-sensitive Ca<sup>2+</sup> was depleted, Ba<sup>+2</sup> induced the tonic contraction. After the pretreatment of lanthnum or verapamil, Ba<sup>+2</sup> did not induce contraction. Ba<sup>2+</sup>-inducedcontraction was suppressed by extracellular K<sup>+</sup> in the normal Tyrode s solution and that was dependent on K<sup>+</sup> concentration. Suppressive effect of K<sup>+</sup> (14 mM) on the Ba<sup>2+</sup>-induced contraction was also dependent on the intracellular Ca<sup>2+</sup> concentration. From the above resuts, it is suggested that Ba<sup>+2</sup> activate indirectly the contractile process by promoting the mobilization of intracellular Ca<sup>2+</sup> and the influx of extracellular Ca<sup>2+</sup>. It is also suggested that action of Ba<sup>+2</sup> on the Ca<sup>2+</sup>-activated K<sup>+</sup> channel can result in the depolarization of cell membrane in the rabbit renal artery.
수소이온농도 변화의 수축물질에 따른 가토신동맥 수축에 미치는 영향과 기전
장석종,김세훈,전병화,박해근,Chang, Seok-Jong,Kim, Se-Hoon,Jeon, Byeong-Hwa,Park, Hae-Kun 대한생리학회 1990 대한생리학회지 Vol.24 No.1
The effects of $H^{+}$ on the arterial contraction and their mechanisms were investigated in the renal artery of a rabbit. The helical strips of isolated renal artery were immersed in the HEPES-buffered or $CO_{2}/HCO_{3}^{-}$-buffered Tyrode's solution. The contractions induced by agonists (norepinephrine, histamine, serotonin and angiotensin II) or high $K^{+}$ were observed with change of extracellular or intracellular $H^{+}$ concentration. The contractions induced by norepinephrine, histamine, serotonin, angiotensin II or high $K^{+}$ in HEPES-buffered Tyrode's solution were inhibited by increase in extracellular $H^{+}$ concentration and potentiated by decrease in extracellular $H^{+}$ concentration. The degrees of these effects were most evident in the contraction induced by serotonin and angiotensin II, moderate in those by histamine and high $K^{+}$, and least in those by norepinephrine. Maximal contraction by norepinephrine, histamine and high $K^{+}$ were not influenced by change in extracellular $H^{+}$ concentration, but influenced in those contration by serotonin and angiotensin II. The attenuated contractions by an acidic pH were not returned to the level of contraction at normal pH (7.4) by elevation of extracellular $Ca{2+}$ concentration. The agonists (norepinephrine, histamine and serotonin)-induced contractions in $Ca{2+}$-free Tyrode's solution were also attenuated by increase in extracellular $H^{+}$ concentration and potentiated by decrease in extracellular $H^{+}$ concentration. Elevation of $Pco_{2}$ in the $CO_{2}/HCO_{3}^{-}$-buffered Tyrode's solution, which increase the intracellular $H^{+}$ concentration, at constant extracellular pH (7.4), increased the contraction by 30 mM $K^{+}$. From the above results, it is suggested that the decrease in contractions by increase in extracellular $H^{+}$ concentration may be resulted from that $H^{+}$ make the receptors less sensitive to agonists and cell membrane hyperpolarize and then inhibit the $Ca{2+}$ influx as well as $Ca{2+}$ release from intracellular $Ca{2+}$ storage site.
조덕주 ( Jo Deog Ju ),전병화 ( Jeon Byeong Hwa ),김성훈 ( Kim Seong Hun ),이상수 ( Lee Sang Su ),손우석 ( Son U Seog ),장연규 ( Jang Yeon Gyu ),목정은 ( Mog Jeong Eun ) 대한산부인과학회 2003 Obstetrics & Gynecology Science Vol.46 No.8
Cerebrovascular disorders (infarction and intracranial hemorrhage), otherwise collectively referred to as stroke, are an uncommon and feared complication of pregnancy. Collectively, these disorders contribute up to 12% of all maternal deaths. Because of t
가토 신동맥 평활근에서 Strontium의 Calcium 대행역할
장윤철(Chang, Yun-Cheol),전병화(Jeon, Byeong-Hwa),장석종(Chang, Seok-Jong) 대한생리학회 1990 대한생리학회지 Vol.24 No.2
The Ca<sup>2+</sup>-substitutional$</TEX> roles of strontium for the contractile processes were investigated in the rabbit renal artery. The contractions induced by either norepinephrine or high K<sup>+</sup> in the condition which intra- and extracellular Ca<sup>2+</sup> were replaced by Sr<sup>2+</sup>, i.e. Sr<sup>2+</sup>-mediated contractions, were dose-dependent. And then the maximal amplitude of contraction, as compared with Ca<sup>2+</sup>-mediated contraction, was about 50% in norepinephrine and about 70% in high K<sup>+</sup>. The Sr<sup>2+</sup>-mediated contractions were independent in the contraction by norepinephrine 10<sup>-5</sup>M) but dependent in those by high K<sup>+</sup>(100 mM) on the extracellular Sr<sup>2+</sup> concentration. Also Sr<sup>2+</sup>-mediated contractions induced by norepinephrine were observed in the Sr<sup>2+</sup>-free Tyrode s solution. The Sr<sup>2+</sup>-mediated contractions induced by either norepinephrine or high K<sup>+</sup> were suppressed by verapamil, a Ca<sup>2+</sup>-channel blocker. By extracellular addition of Sr<sup>2+</sup>, the Ca<sup>2+</sup>-mediated contractions induced by norepinephrine 10<sup>-5</sup>M) or 40 mM K<sup>+</sup> were inhibited but those by high K<sup>+</sup>(100 mM) were increased. And the Sr<sup>2+</sup>-mediated contractions were increased by extracellular addition of Ca<sup>2+</sup> but did not reach the level of Ca<sup>2+</sup>-mediated contraction. Therfore it is suggested that in the vascular smooth muscle of rabbit renal artery Sr<sup>2+</sup> could enter the smooth muscle cells easily through the potential-operated calcium channel (POC) but not easily through the receptor-operated calcium channel (ROG), and Sr<sup>2+</sup> might be stored in the intracellular Ca<sup>2+</sup>-binding site and released by NE and induced the contraction by a way of activating directly the contractile apparatus.
김성훈 ( Kim Seong Hun ),이상수 ( Lee Sang Su ),전병화 ( Jeon Byeong Hwa ),길준철 ( Gil Jun Cheol ),손우석 ( Son U Seog ),목정은 ( Mog Jeong Eun ),이은혜 ( Lee Eun Hye ) 대한산부인과학회 2004 Obstetrics & Gynecology Science Vol.47 No.3
Foreign bodies retained in the peritoneal cavity rarely are documented, owing to medical, legal, and other reasons. A retained surgical sponge in the peritoneal cavity may cause symptoms both in the early postoperative period as well as months or years after the original operation. Among the complications reported following retention of surgical pads and sponges are obstruction, peritonitis, adhesions, abscess formation, erosion into the gastrointestinal lumen, and extrusion via the rectum. Erosion of a surgical sponge into the bowel is uncommon. We report a 33-year-old women in whom retained surgical sponge eroded into the small bowel and produced unusual radiologic findings and complications.