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우울 증상이 호전된 비우울 집단과 우울집단 간의 인지요인의 비교
장유경(You-Kyung Jang),장세헌(Se-Heon Jang),제영묘(Young-Myo Jae),이대수(Dae-Su Lee),홍성욱(Sung-Wook Hong),윤창영(Chang-Young Yun) 대한생물치료정신의학회 2007 생물치료정신의학 Vol.13 No.2
본 연구는 우울증으로 진단받고 약물치료 후 우울증상이 잔존하는 우울군과 증상이 관해된 비우울군간의 인지요인의 특성을 비교분석하고자 하였다. 한국형우울척도(KDS)를 사용하여 우울군(n=18)과 비우울군(n=28)으로 나누었다. 자동적 사고 척도, 역기능적 태도척도, 귀인양식 척도를 시행하여 인지적 특성을 살펴보았다. 자동적 사고 척도에서는 두 군간의 유의미한 차이가 있었으며, 자동적 사고척도는 KDS와 강한 상관관계가 있었다. 역기능적 태도 척도와 귀인양식에서는 두 군간 의미있는 차이를 보이지 않았다. 이러한 연구 결과를 토대로 본 저자는 자동적 사고는 기분 상태 의존적인 인지요인이며 역기능적 태도와 귀인양식은 아마도 개인의 영속적인 특질을 반영하며 우울증과 관련하여서 자동적 사고에 비해 보다 지속적으로 영향력을 미치는 것으로 보았다. 따라서 우울 증상의 재발에 취약할 수 있는 기저의 우울 생성적 인지 요소를 제거하기 위해서는 약물치료에 의한 표면적인 우울증상의 감소 외에 보다 적극적인 치료적 개입이 요구됨을 제안하였다. Objectives:This study was performed to compare the cognitive factors between recently recovered non-depressed group and currently depressive group. Methods:To measure the degree of depressive mood, KDS(Korean Depression Scale) was used. We divided patients in two groups. One is recently recovered non-depressive group(n=28) and the other is currently depressive group(n=18) during antidepressant medication. To assess the cognitive state, we administered DAS(dysfunctional attitude scale), ASQ(attributional style questionnaire), and negative ATQ(automatic thought questionnaire). Results:In ATQ score, there was a significant difference between two groups(t=3.453, p=.002). ATQ score strongly correlated with KDS score(r=.786, p<0.01). But, there was no significant differences between two groups in mean scores of DAS and all positive and negative attributional style subscales, even though DAS score correlated with KDS score significantly(r=.383, p<0.01). This means that ATQ score decreased according to remission of depression. But DAS and especially negative attributional style score didn’t changed even though improvement of depression with antidepressant medication. Conclusions:We concluded that automatic thoughts were the mood state-dependent cognitive factor and dysfunctional attitude and attributional styles were cognitive factors that maybe reflect more permanent personal traits and underlying vulnerabilities of depression than automatic thoughts. We also concluded that the additive treatments more than antidepressant medication would be needed to change the dysfunctional attitudes and attribution styles, which could possibly act as the depressogenic factors in recently recovered non-depressive patients during maintenance antidepressant medication.
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인유 , 조제 분유 및 시유의 총지방질 조성 , 총지방산 조성 및 비타민 E 함량의 비교
윤태헌,임경자,장유경 ( Tai Heon Yoon,Kyung Ja Im,You Kyung Jang ) 한국유화학회 1984 한국응용과학기술학회지 Vol.1 No.1
The lipid and fatty acid compositions and vitamin E content were analyzed in 48 human mature milk, 3 infant formulas (modified milk powder) and 8 market milk samples. The total lipid content in modified milk powder was similar those in human milk and market milk when total solids content of modified milk powder was corrected to that of human milk. In comparison with human milk, modified milk powder contained a lower proportion of triglycerides and higher proportions of phospholipids, free fatty acids and cholesterol esters. The ratios of phospholipids/ triglycerides, total cholesterol/ triglycerides and total tocopherol/ total lipids in modified milk powder were significantly higher than those in human milk and market milk. The American recommendation fro linoleic acid (0.7 IU/g) could be satisfied with human milk, modified milk powder and market milk. The proportions of short-and medium-chain even numbered saturates were higher and the proportions of long-chain derivatives of linoleic (ω6 series) and linolenic (ω3 series)acids were lower in modified milk powder and market milk than in human milk. It is concluded that in view of their levels in breast milk, the polyenoic derivatives of linoleic and linolenic acids must be taken into account when assessing infant foods.
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급성 신부전, 패혈증 환자에게 척수강내 약물 주입 펌프 삽입 1례: 증례보고
김량규 ( Raing Kyu Kim ),장유경 ( You Kyung Jang ),성현영 ( Hyun Young Seong ),신영재 ( Young Jae Shin ),고재철 ( Jae Chul Koh ) 경희대학교 경희의료원 2020 慶熙醫學 Vol.35 No.1
The implantable intrathecal drug delivery pump has been widely used for patients with severe intractable pain. Though it can be effectively used when there are side effects or tolerance caused by using high-dose opioids, in a patient with an unstable condition, such as sepsis or organ failure, one might be hesitated to use such an invasive procedure. Nevertheless, terminal cancer patients are often unstable and many patients are still suffering from pain without the help of the procedure. In this case report, we report an intrathecal drug delivery pump insertion in a terminal cancer patient with repeated acute renal failure and sepsis. The procedure was performed under general anesthesia, with careful attention to the various catheters on the patient’s body which could potentially be obstructed or cause surgical field contamination. After the procedure, the patient showed significant pain reduction, reduced opioid intake, and improved quality of life without specific side effects.
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윤태헌(Tai Heon Yoon),장유경(You Kyung Jang) 한국식품영양과학회 1983 한국식품영양과학회지 Vol.12 No.1
알맞은 수준의 linoleic acid섭취시에는 5,8. 11-eicosatrienic acid가 혈장에서 미량 검출되지만 식이에 linoleic acid가 없거나 부족할 경우 5, 8, 11-ei-cosatrienoic acid가 증가하고 반면에 linoleic acid와 arachidonic acid는 감소한다. 뿐만 아니라 피부염, 탈모, 미토콘드리아 기능 변화, 모세관 취약성, 조직 변화 등의 변화가 일어난다. EFA결핍의 발현에 식이의 EFA부족 그 자체는 물론 단백질 부족, 고콜레스테롤혈증을 일으키는 인자들, 당뇨병, 다발성 경화증, 동맥 경화증 등 여러 요소들이 영향을 미치고 있다. EFA결핍은 특히 여러 가지 임상적 요인으로 인하여 장기간의 무지방 비경구 영양을 공급받는 환자에서 자주 보고되고 있는데, 거의 대개 지방 유탁액의 정맥 주사로 예방내지 치료한다. EFA결핍을 미연에 방지하기 위한 linoleic acid의 섭취량은 환자의 연령이나 지방 유탁액의 투여 방법에 따라 다르지만 EFA 결핍으로 인한 생화학적 비상정적인 상태의 경우 경구적으로 최소한 총 칼로리의 1%를, 비경구적으로는 2%를 공급하여 주면될 것이다. The recent work on symptomatology and therapy of essential fatty acid (EFA) deficience has been reviewed EFA deficiency is due to an absence of dietary linoleic acid which cannot be synthesized endogenously in man.<br/> The diagnosis of EFA deficiency is based on clinical features such as the appearance of scaly skin rash, sparse hair growth or failure to thrive, which occur late in the course of EFA deficiency and biochemical features occurring within two weeks of fat-free diet. The amount of linoleic acid required to prevent EFA deficiency varies with age of the patient and route of fat administration.
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윤태헌(Tai Heon Yoon),임경자(Kyung Ja Lim),장유경(You Kyung Jang) 한국식품영양과학회 1982 한국식품영양과학회지 Vol.11 No.3
초유 및 성숙유의 지방질 조성을 TLC-FID 방법으로 분석, 정량하였던 바 분리된 지방질 성분 중 triglyceride 수준이 초유에서보다 성숙유에서 유의하게 높았으며, 기타의 지방질 성분들은 초유 및 성숙유간에 유의한 차이가 나타나지 않았다. Lipid composition of human milk samples (ten colostrum and 10 mature) was analyzed by quantitative thin-layer chromatography with flame ionization detector. Six kinds of lipid components existed in human milk. Among them, triglyceride which was most abundant lipid component showed significantly lower levels in colostrum than in mature milk. Other lipid components have no significant differences between colostrum and mature milk.
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