http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : 장아람 ( Ah Ram Chang ) (검색결과 2 건)
- 무료
- 기관 내 무료
- 유료
-
이미연(Me Yeon Lee),장아람(Ah Ram Chang),김학재(Hak Jae Kim),김규보(Kyubo Kim),김진호(Jin Ho Kim),박찬일(Charn Il Park),하성환(Sung Whan Ha),우홍균(Hong-Gyun Wu),김일한(Il Han Kim) 대한방사선종양학회 2007 Radiation Oncology Journal Vol.25 No.4
목 적: 데스모이드 종양의 수술 후 방사선치료 성적을 분석하고 예후인자를 평가하기 위하여 후향적 연구를 진행 하였다. 대상 및 방법: 1984년 6월부터 2005년 10월까지 서울대학교병원에서 데스모이드 종양으로 수술 후 방사선치료를 시행 받은 환자 27명에 대한 의무기록을 분석하였다. 남자 13예, 여자 14예였으며 연령은 3∼79세였다(중앙값, 28 세). 종양은 복부 외(21예), 복벽(6예)에 위치하였고 종양의 크기는 장경 기준 2.5∼25 cm (중앙값, 7.5 cm)였다. 첫 수술 후 방사선치료를 받은 환자가 13예, 국소 재발 종양에 대한 반복 수술 후 방사선치료를 받은 환자가 14예 였다. 방사선치료는 분할 선량 1.8∼2.0 Gy로 총 45∼66 Gy (중앙값, 59.4 Gy)를 조사하였다. 결 과: 추적관찰 기간의 중앙값은 61개월(범위, 12∼203개월)이었다. 병변의 국소 진행은 2예에서, 국소 재발은 6예에서 관찰되었다. 5년 무병생존율과 5년 무진행생존율은 각각 61%와 70%였다. 다변량 분석 결과 광범위절제술을 시행한 경우 용적축소수술을 시행한 경우보다 무병생존율이 높았고(p=0.028), 첫 수술 후 방사선치료를 시행하는 경우와(p=0.046) 방사선 선량이 60 Gy 이상인 경우에(p=0.049) 무진행생존율이 높았다. 첫 수술 후 방사선치료를 시행한 경우 최종 관찰까지 수술 횟수가 중앙값 1회(범위, 1∼3회)였으나 첫 수술 후 방사선치료를 시행하지 않은 경우 수술 횟수가 중앙값 3.5회(범위, 2∼6회)였다(p<0.001). 결 론: 처음 진단 시 수술 후 방사선치료를 시행한 경우 국소 제어율은 높았고 총 수술 횟수는 적었다. 따라서 재발의 위험도가 높은 용적축소수술을 받은 환자 등에서는 수술 후 조기 방사선치료의 시행이 바람직하다. Purpose: This retrospective study was conducted to assess outcome and to determine the prognostic factors in patients with a desmoid tumor treated with postoperative radiotherapy. Materials and Methods: Twenty-seven patients with a desmoid tumor who were treated with postoperative radiotherapy between June 1984 and October 2005 were analyzed. There were 13 male and 14 female patients. The age of the patients ranged from 3 to 79 years (median age, 28 years). Tumors were located in an extra-abdominal area (21 cases), and in the abdominal walls (6 cases). The tumor size ranged from 2.5 to 25 cm (median size, 7.5 cm) in the largest linear dimension. Thirteen cases received radiotherapy after initial surgery, and 14 recurrent cases received radiotherapy after additional surgery. The total radiation dose given was 45∼66 Gy (median dose, 59.4 Gy), and the fraction size was 1.8∼2.0 Gy. Results: The median follow-up period was 61 months (range, 12∼203 months). Two patients developed local progression and six patients experienced local recurrence. The 5-year disease-free survival rate and the 5-year progression-free survival rate were 61% and 70%, respectively. Wide local excision was associated with better disease free survival with statistical significance (p=0.028). Radiotherapy after initial surgery (p=0.046) and a higher radiation dose of more than 60 Gy (p=0.049) were associated with better progression free survival with statistical significance. At the time of the last follow-up, the number of additional surgeries was higher in patients that received radiotherapy after reoperation (p<0.001). Conclusion: Radiotherapy after the initial operation improved local control and decreased the number of subsequent operations. Thus, postoperative radiotherapy after an initial operation is recommended in patients with a high risk of recurrence for a desmoid tumor.
-
정윤호 ( Yun Ho Jung ),최현숙 ( Hyun Sook Choi ),천영국 ( Young Koog Cheon ),문종호 ( Jong Ho Moon ),조영덕 ( Young Deok Cho ),장아람 ( Ah Ram Chang ),원종호 ( Jong Ho Won ) 대한소화기학회 2011 대한소화기학회지 Vol.58 No.5
Background/Aims: CyberKnifeTM stereotactic body radiotherapy (SBRT) has been thought as a promising treatment modality for inoperable or recurred pancreaticobiliary malignancies. But, clinical course of CyberKnifeTM treatment have not been established yet, so we report the experience of CyberKnifeTM treatment in 19 patients with recurred or advanced pancreaticobilliary malignancies. Methods: Between July 2008 and May 2009, 19 patients (gallbladder cancer 4, common bile duct cancer 5, and pancreatic cancer 10) with recurred (12) and advanced pancreaticobiliary cancer (7) underwent CyberKnifeTM treatment in Soonchunhyang University Hospital. Tumor size was evaluated at 1, 3, 6, 8 and every 3 months after SBRT. Results: The mean age was 60.2 years, and the mean size of target lesions was 28.1±1.30 mm. After CyberKnifeTM treatment, the average size of target lesions was decreased; 2.53±4.18 mm from months 0-1 in 19 patients, 2.47±4.7 mm from months 1-3 in 15 patients, 0.08±5.11 mm from months 3-6 in 12 patients. However, the average size of target lesions was increased 3.67±8.98 mm from months 6-8 in 6 patients. There were 2 cases of massive duodenal ulcer bleeding after CyberKnifeTM treatment, one of them expired due to ulcer bleeding. Also, other minor complications appeared such as 1 case of abdominal pain and 1 case of diarrhea. Conclusions: CyberKnifeTM treatment seems to be effective in local control of pancreaticobiliary cancer, but we experienced serious complications. Further prospective studies will be needed for the proper evaluation of role of CyberknifeTM treatment in patients with advanced pancreaticobiliary malignancies. (Korean J Gastroenterol 2011;58:264-269)
ScienceON
스콜라연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
