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일부(一部) 농촌지역고혈압(農村地域高血壓) 환자(患者)에 대(對)한 위험요인(危險要因)으로서의 생화학적검사치(生化學的檢査値)에 관(關)한 연구(硏究)
장순모 ( Soon Mo Chang ),윤영옥 ( Young Ok Yoon ) 대한임상검사과학회 1984 대한임상검사과학회지(KJCLS) Vol.16 No.1
This study was carried out in Chun cheon City and Chunseong county in 1984, in order to identify the relationship between biochemical test values and hypertension. Biochemical test items were HDL-C, VLDL-C, total cholesterol , triglyceride and uric acid. The results obtained were as follows: 1. The mean values of this biochemical tests in normal control group were 46±13mg/dl for HDL-C, 25±16mg/dl for VLDL-C, 88±22mg/dl for LDL-C, 3.6±1.1 for T-Cholesterol/HDL-C Ratio, 2.1±1.0 for LDL-C/HDL-C ratio, 157±28mg/dl for T-Cholesterol, 150±76mg/dl for triglyceride, 4.1±1.4mg/dl for uric acid. 2. The mean values of the tests in hypertensive group were 40±10mg/dl for HDL-C, 30±18mg /dl for VLDL-C, 97±26mg/dl for LDL-C, 4.4±1.3 for T-Cholesterol/HDL-C ratio, 2.6±0.9 for LDL-C/HDL-C ratio, 168±32mg/dl for T-Cholesterol, 200±123mg/dl for triglyceride, 4.9±1.9 mg/dl for uric acid. 3. The values of HDL-C was lower significantly in hypertensive group than in control group. 4. The values of VLDL-C, LDL-C, T-Cholesterol/HDL-C ratio, LDL-C/HDL-C ratio, T-Cholesterol, T.G. and uric acid were higher significantly in hypertensive group than in contral group.
장순모 ( Soon Mo Chang ) 대한임상검사과학회 2000 대한임상검사과학회지(KJCLS) Vol.32 No.3
Most of posttransfusion hepatitis will be developed by hepatitis C virus. So the ultimate goal of blood donor screening of anti HCV antibodies is specific exclusion of viral carrier from the blood donor population. To evaluate whether various enzymatic immunoassay for anti HCV antibodies are an useful methods to rule out viral carrier or not, the author investigated the sensitivity and specificity of various 2nd generation anti HCV reagent. There were noticed some false positive and false negative by different reagent and also demonstrated same results with control sample confirmed by RT-PCR. From these results it is suggested that 3rd generation anti HCV antibody should be adopted for screening of donor blood.
갑상선 질환에서 혈청 Microsome 항체 측정의 의의
윤영옥 ( Young Ok Yoon ),장순모 ( Soon Mo Chang ),박호자 ( Ho Ja Park ),이준옐 ( Jun Yoel Lee ),양기화 ( Ki Hwa Yang ),정인숙 ( In Sook Chung ),강석진 ( Seok Jin Gang ) 대한임상검사과학회 1984 대한임상검사과학회지(KJCLS) Vol.16 No.1
Since Roitt and his associates discovered antithyroglobulin antibody in serum of the patient with Hashimoto`` s thyroiditis, in 1956, several anti-thyroid autoantibodies were discovered, and have been attributed to the diagnosis of thyroid disease. The authors investigated the incidence and titers of antimicrosomal antibody in the 515 patients with various thyroid disease from October, 1981 to December, 1983, and 104 normal healthy persons, measured by tanned red cell hemagglutination technic. 1) Twenty healthy males were all negative, and ten (11.9%) out of eighty-four healthy female were positive. 2) The disease group with high positive rate included Graves`` disease; 222 cases (91.4%) out of 243 cases, Hashimoto``s disease; 112 cases (92.6%) out of 121 cases, all eight cases of postpartum thyroiditis. 3) The disease group with low positive rate included non-toxic nodular goiter; 14 cases (17.5%) out of 80 cases, non-toxic diffuse goiter; 11 cases (31.4%) out of 35 cases, thyroid tumor; 2 cases (11.1%) out of 18 cases, subacute thyrolditis; 3 cases (30%) out of 10 cases. 4) In 32 cases of Graves`` disease that were follow up more than three times, the titers of anti-microsomal antibody reveal marked fluctuation. In summary, although the positive rate of the anti-microsomal antibody in the Graves disease, Hashimoto``s disease and postpartum thyroiditis, reveal diagnostic significance, the titer of the anti-microsomal antibody which examine in one point, cann`t contribute to reflect the severity of the disease, because of the titer is fluctuated during the course of the disease.
장상우 ( Sang Wu Chang ),서한익 ( Han Ik Sur ),김대식 ( Dae Sik Kim ),김양호 ( Yang Ho Kim ),김영활 ( Young Hwal Kim ),여영규 ( Young Gyu Yeo ),장순모 ( Soon Mo Chang ),민재기 ( Jae Gi Min ),조영주 ( Young Ju Cho ) 대한임상검사과학회 1999 대한임상검사과학회지(KJCLS) Vol.31 No.2
Pareto ana1ysis through qua1ity improvement activities is the study of related subjects to determine if one is more significant than the others and used to identify the most important item in group of items. The Pareto chart breaks down an item into its component parts and then arranges and displays those parts in order of importance. Pareto ana1ysis is used to focus problem-solving activities, so that the area causing the most difficulty is addressed first. We eva1uated error problems in c1inica1 chemistry laboratory from J anuary 1997 to December 1998. We used systems thinking for cause and effect diagram for problem-solving and Pareto analysis to solve the problem factors of ana1ytica1 performance of Hitachi 7150 system for two years. We found that tota1 problems reduced 33.5 percentage during one year after educating system thinking, cause and effect analysis. We conc1uded that 8 1. 19 percentage of the total problems controlled by 23% of the items that are two factors. Upon examination, this 80/20 rule(Pareto distribution) proved true in our working area. We use the Pareto distribution to achive an 80% qualiη improvement by working 20% of the problem causes. We think Pareto an떠ysis is a tool for problem-solving during quality improvement activities for total quality management in medical laboratory science.