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        실험계획법을 이용한 표면처리공정의 최적화

        장순명 ( Soon-myung Chang ),권혁무 ( Hyuck-moo Kwon ),홍성훈 ( Sung-hoon Hong ),이민구 ( Min-koo Lee ) 대한설비관리학회 2017 대한설비관리학회지 Vol.22 No.2

        Mintage industry is getting more competitive in the global market due to the reduction of the native market in accordance with the change of social environment; therefore many corporators are attempting monopolistic supply through specific standard setting. The purpose of this study is to determine the optimum conditions of the surface treatment process which influences the new paper pH. In this paper, DOE (Design Of Experiments) is used to determine the optimum condition of the surface treatment process for practical field application. The output variable was selected as paper pH and the input variables were selected as four chemicals. The experiments were conducted as full factorial experiments by 2-level, 4-factors. Through the design of experiments, the results of this study verified main effects and interaction effects of the input variables, derived a regression model and optimum conditions of the surface treatment process for paper pH using the response optimizer.

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      • 체외순환과 대사에 대하여

        김종환,장순명,송요준,노준량,서경필,이영균 中央醫學社 1974 中央醫學 Vol.26 No.5

        The clinical cases of twenty consecutive intracardiac operations under the cardiopulmonary bypass with the disposable bubble oxygenator of RyggKyvsgaard and the Sigma Motor pump during past 3 months were reviewed to evaluate the effects of the extracorporeal circulation on the body by observing the hematologic and metabolic studies. The hematological examinations observed periodically revealed the effect of hemodilution with the lowered hemoglobin and- hematocrit values with which patients did well, and the tendencyy of mild anemia continuing even on dismissal from hospital. The platelet counts were decreased markedly along with the bypass and remained rather low after the operation in most cases. However, these. alterations did not result in clinically related significant complications. On the other hand, the changes in the serum electrolytes were minimal being kept in the near physiological range including calcium and magnesium levels_ Though, additional amounts of potassium were administered to keep the serum. potassium level a little high to avoid possible occurrence of cardiac arrhythmias after surgery. The metabolic effects of extracorporeal circulation on the body were studied with the arterial blood gas analyses performed on the blood samples taken periodically before, during and after bypass. The general tendency was toward moderate respiratory alkalosis during perfusion and mild metabolic acidosis with the result of keeping the pH values within the normal range. The respiratory component of the alterations were mainly the moderately lowered carbon-dioxide tension in the blood during perfusion rising only to normal level with the termination of the bypass. It was suggested that the addition of small amounts "of carbon dioxide to the oxygenator along with the sufficient amount of 'oxygen -may be beneficial to avoid these potentially dangerous respiratory imbalance .during perfusion. The metabolic acidosis present before perfusion weremuch corrected toward normal with perfusiorz'-probably from the result of bicarbonate .added during and after surgery. However, these metabolic acidosis were not so :severe that extraordinary amounts of bicarbonate should be given for the cor section. The average amount of bicarbonate given during and after perfusion was 133.8 mEq. with several cases getting a little more because of the prolonged perfusion. On the whole, the cardiopulmonary bypass was carried out successfully with the only mild deviation of the observed data from normal physiological values. There were 6 hospital deaths, 30% hospital mortality, 3 out of 10 cyanotic heart ,diseases, 2 out of 4 ventricular septal defects, none of 3 atrial septal defects and 1 out of 4 prosthetic valve replacements in 3 cases. The complications seen in the survivors from surgery were not definitely related to the bypass itself.

      • 同種肝臟移植에 關한 實驗的 硏究 -豫報-

        金洙泰,朴哲圭,蔣舜明,金鏞日,朴容眩,洪俊浩,吳壽明,羅成均,金晋煥 최신의학사 1970 最新醫學 Vol.13 No.4

        Preliminary experiment of six auxiliary and four orthotopic canine hepatic allotransplantation was undertaken in this laboratory in 1969. Buster's and Hori' s methods and the other modifications were tried for six auxiliary and four orthopic allogenic transplantation avoiding the use of venous bypass. The one method <Fig. l-(3)> for the recipient procedure, is followed by: 1. Side to side portacava1 shunt, 2. Right hepatectomy, 3. Orthotopic allotransplantation, 4. Left hepatectomy. The two cases of survival, 10 days and 45 days respectively, were observed in the cases of auxiliary heterotopic allotransplantation, and the latter case is still alive at the time of this roport. On the 6th postoperative day, liver scanning revealed the graft is still in function in the former case. The necrosis of graft liver was noted upon autopsy on the 10th postoperative day. The liver function and C. B. C. were checked at a few days interval after transplantation in the latter case. Within 4 weeks, the liver function had become almost within normal limits, but the elevation of alkaline phosphatase is still persistent. His general condition appears to be healthy.

      • 개(犬)에서의 腎臟移植 硏究 : 移植腎의 病理組織所見 및 常壓低溫灌流保存에 關하여

        金洙泰,金晋煥,金宇基,朴哲圭,洪俊浩,吳壽明,兪明鍾,金鏞日,朴容眩,蔣舜明,池堤根 최신의학사 1970 最新醫學 Vol.13 No.3

        Canine renal transplantation was done in this laboratory in 1969. 1. The six dogs of fourteen autografts were observed for six months. All of them showed weight gain from the postoperative immediate debilitated states at the end of postoperative one month. 2. The five dogs of renal homografts into an untreated recipients with immunosupnressive drug survived for seven days on the average. 3. In the eight cases of inguinal homografts treated with azathioprine or azathioprine and prednirsolone, the transplanted kidneys could discharge clear urine for 15 days on the average from -the ureterostomy on the abdominal wall. One of them continued urination until the postoperative 24th day at the time. of removing the graft. 4. The kidneys perfused using continuous flow rate of 320 m1/hr for three or four hours with 4°C 1,000 ml of Ringer's lactate solution containing heparin 50mg and procaine t gm revealed almost normal histological architectures. 5. The six homografts perfused for three hours using the above stated method could discharge clear urine for 4. 5 days on the average. One of them continued clear urination until the postoperative 7th day at the time of removing the graft. 6. The six homografts perfused for four hours using the same method continued urination for 3.8 days except one kidney which was missed due to death of the recipient from severe bleeding from the surface of the kidney within 24 hours after transplantation.

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