Effect of Maternal Dietary Restriction on Serotonin and Catecholamine Levels of the Developing Rat Brain

Kyung-Ja Chang(장경자),Haymie Choi(최혜미) 韓國營養學會 1985 Journal of Nutrition and Health Vol.18 No.1

타우린과 베타알라닌이 실험적 당뇨유발 쥐의 혈당 및 혈중지질농도에 미치는 영향

장경자(Chang Kyung Ja) 韓國營養學會 1999 Journal of Nutrition and Health Vol.32 No.3

저열량균형식, 운동 및 행동수정에 의한 비만여성의 치료에 관한 연구

장경자(Kyung-Ja Chang) 한국식품영양과학회 1995 한국식품영양과학회지 Vol.24 No.4

체지방이 30% 이상으로 비만이라 판정되는 20~62세의 지원자들에게 저열량 균형식, 무리하지 않은 유산소 운동 및 개인별 비만의 원인을 교정하고 평생체중을 조절하기 위한 영양상담과 교육을 포함한 행동수정을 통해 5주 동안 비만을 치료하고 성인병과 관련된 위험 요인들의 변화를 살펴보았다. 활동량, 식습관, 식이섭취조사를 실시하여 개인별 비만의 원인을 진단한 후 잘못된 식생활을 교정할 수 있도록 주 3회의 영양상담과 매주 1회의 영양교육을 실시하였다. 식이요법은 1일 1끼의 식사와 3회의 조제식이를 통해 열량이 1200㎉ 정도가 되고, 양질의 단백질, 비타민, 무기질은 성인 권장량의 100~150% 이상이 되도록 하였다. 식전에 식이 섬유와 물을 복용하고 식사 기간은 20분 이상으로 천천히 섭취하도록 하였으며, 튀긴음식, 가공식품, 패스트푸드, 술, 청량음료, 달고 기름진 음식, 짜고 자극적인 음식 등은 제한하였다. 주당 3~5일간 1시간 정도의 가벼운 유산소 체조를 실험대상자 전원이 모여서 실시하였다. 먹은 식품, 활동, 운동, 감정상태, 피로여부 등을 일지로서 기록하게 하여 상담을 통해 교정하고 관찰하여 긍정적인 내적동기를 갖도록 교육하였다. 비만치료기간 중 탈락한 대상자의 수는 총 16명 중 5명(31.3%)이였으며, 비만도는 대상자의 대부분이 경증이고, 불규칙적인 식사, 빨리 먹는 습관, 과식, 짜게 먹는 습과, 야식, 음주 등의 비만의 원인이 되는 습관들을 가지고 있어 식습관 점수는 개선이 요구된다고 진단되었다. 5주 동안의 비만치료로 체중은 평균 4.8㎏(주당 0.96㎏)이 감량 되었으며, 체지방, body mass index, 허리, 팔, 둔부의 둘레가 유의적으로 감소되었다. 혈압, 공복시의 혈당, 혈액중의 중성지방, 총콜레스테롤, HDL-콜레스테롤은 변화가 없었으나, LDL-콜레스테롤은 유의적으로 감소하였다. A multidisciplinary weight control program was conducted for obese women. The major components of the program included low calorie diet therapy, exercise, behavior modification and nutritional education and counseling. Sixteen healthy volunteers in excess of body fat, above 30%, were enrolled in the group support program. But 5 person were dropped out in the 2nd week of treatment. During the 1st week of group orientation, individual cause of obesity was assessed through a computer program including survey of dietary intake, activity, eating habits and life styles. During the 5 weeks of treatment, 4.8㎏ of average weight loss was accomplished using a following program ; low calorie diet(1200㎉/day with all essential nutrients), low impact aerobic exercise (50~60% of VO₂max , 1 hour/day in a group, 3~5 days/week), behavior modification of individual life styles and eating habits causing obesity and nutritional education concerning nutrition, role of exercise such as brisk walking, importance of slow eating in regular meal pattern and internal motivation for weight reduction, health risk of obesity and rapid weight loss, weight recycling and yo-yo syndrome, etc. Nutritional counseling was conducted 3 times per week with checking self-records of foods, activity, emotional state and tiredness. Before and immediately after 5 weeks of treatment, blood pressure, fasting blood glucose, cholesterol and triglyceride were measured and compaired with paired t-test. After 5 weeks of treatment, body weight, body mass index, body fat and circumferences of waist, upper arm and hip were significantly decreased. Also LDL-cholesterol was significantly decreased after obesity treatment.

Effect of Maternal Undernutrition on the Growth and Composition of Young Rat Brain

Kyung-ja Chang(장경자),Haymie Choi(최혜미) 韓國營養學會 1981 Journal of Nutrition and Health Vol.14 No.2

인천시 주부의 풍미 증진제에 대한 인식실태

장경자,차원,Chang, Kyung-Ja,Cha, Won 대한지역사회영양학회 2000 대한지역사회영양학회지 Vol.5 No.4

The purpose of this study was to investigate the perception and use of flavor enhancer products. This study was carried out through questionnaire and the subjects were 503 housewives in Inchon. The results are summarized as follows. As for age, 51.9% of the subjects were 40 years or older. Also, 60.0% of the subjects had received a high school education. As for occupation, full-time housewives accounted for 63.7%. Monthly household income of most subjects were 1 million won or more, and monthly food expenses of most subjects were 300 thousand won or more. Also 71.0% of subjects lived in apartments. As for taste of flavor enhancer products, 58.3% of subjects perceived that it was mediocre, 31.3% said good, 6.2% said bad, and 1.8% said very bad. Most subjects perceived that the convenience of flavor enhancer products was good and there was a significant difference among the groups divided by education level. As for economy of flavor enhancer products, there were significant differences among groups divided by household income and food expenses. Most subjects perceived that the safety of flavor enhancer products was not good. Most subjects considered the date of manufacture, manufacturers, food additives, packaging and price when they purchased flavor enhancer products. Also, 70.0% of subjects were going to reduce the amount of flavor enhancer products they use in the future. Most subjects needed flavor enhancer products good for health. Therefore, it may be necessary to develop and to produce safe, nutritious, tasty, cheap and various flavor enhancer products.

일부 지역 대학생의 생활 스트레스, 식행동, 식품 선택에 관한 상관성 연구

성민정,장경자,Sung, Min-Jung,Chang, Kyung-Ja 동아시아식생활학회 2006 동아시아식생활학회지 Vol.16 No.6

This study was performed to investigate stress levels, dietary behaviors and food choices, and their correlations in college students. General characteristic stress scores, using a stress test, and the dietary behaviors and food choices of subjects under stress were measured in 358 subjects (185 males and 173 female). The mean total stress scores of the male and female students were $67.91{\pm}44.85$ and $85.62{\pm}48.91$, respectively. Female students were more stressed than males in relation to family, value, future, friends, and study related factors. There were gender differences in the food intake and frequency of eating sweet things when under stress. Stress increased the food intake and frequency of eating sweet things in female students. Especially, stress factors, such as value, economic, future, friends and study problems increased the food intake of female students. Female students preferred sweet tasting items; whereas, male students preferred hot tasting items when under stress. These results show the effect of life stresses on the dietary behaviors and food choices of college students. Stress not only increased energy consumption in certain individuals, but also changed their food choices. Therefore, education with regard to nutrition is necessary if college students are to practice good eating habits for the correct management of life stresses.

대학생의 영양섭취 실태에 관한 연구

유정순,장경자,변기원 ( Jeong Soon You,Kyung Ja Chang,Ki Won Byun ) 대한가정학회 1994 Human Ecology Research(HER) Vol.32 No.4

일부 지역 대학생의 생활 스트레스와 수면, 신체계측, 영양소섭취 상태와의 상관관계

성민정,장경자,Sung, Min-Jung,Chang, Kyung-Ja 한국식품영양과학회 2007 한국식품영양과학회지 Vol.36 No.7

대학생의 생활 스트레스와 수면, 신체계측, 영양소섭취 상태와의 상관관계를 알아보고자 자기 기입식 설문조사와 신체계측 및 체성분 검사, 식이섭취조사를 실시한 결과는 다음과 같다. 대학생들의 평균 수면 시간은 남학생 7.0시간, 여학생 7.1시간이었고, 수면 점수는 남학생 40.6${\pm}$5.7, 여학생 41.5${\pm}$5.3으로 수면 시간과 수면 점수에 있어 남녀 간에 유의한 차이를 보이지 않았다. 수면과 생활 스트레스 간의 상관관계에서 남녀 모두에게 수면 시간은 생활 스트레스의 수준(스트레스 경험 빈도, 중요도, 총 스트레스 점수)과 상관관계를 보이지 않았으나, 수면의 질을 나타내는 수면 점수와 생활 스트레스 수준(스트레스 경험 빈도, 중요도, 총 스트레스 점수)을 살펴보았을 때, 남녀 모두에게 생활 스트레스와 수면의 질 간에 매우 유의한 음의 상관관계를 보여(p<0.01) 수면의 양보다는 수면의 질이 생활 스트레스와 더 상관이 있음을 보여주었다. 생활 스트레스 경험 빈도, 중요도, 총점과 신체계측 간에 상관성을 보았을 때 남학생은 생활 스트레스 경험 빈도, 중요도, 총점과 신체계측 및 체성분 간에 유의한 상관관계가 나타나지 않았으나 여학생은 생활 스트레스 경험빈도, 총점이 신체발달 점수와 유의한 음의 상관관계를 보였다(p<0.05). 남학생의 경우 경제 문제와 신체계측과의 상관관계에서 체중(p<0.05), 허리둘레(p<0.05), 엉덩이둘레(p<0.05)와 유의적인 음의 상관관계를 보였다. 여학생은 이성 문제에 대한 스트레스와 BMI(p<0.05), 체지방률(P<0.01), 복부지방률(p<0.01), 비만도(p<0.05) 간에 유의적인 음의 상관관계를 보였고, 친구 문제와 BMI(p<0.05), 비만도(p<0.05), 엉덩이둘레(p<0.05)간에 유의적인 양의 상관관계를 보였으며 학업 문제에서 체지방률(p<0.05), 복부지방률(p<0.05)과 유의적인 양의 상관관계를 보였다. 영양소 섭취량과 생활 스트레스와의 상관관계에서 몇몇 영양소와 생활스트레스 간에 유의한 상관성을 보였으며, 생활 스트레스 원인별로 그 양상이 달랐다 남학생은 대체로 동물성 식품으로부터 얻을 수 있는 영양소인 칼슘, 철분 등과 생활 스트레스 간에 양의 상관관계를 보였다. 이상에서 조사된 바에 의하면 대학생의 생활 스트레스는 수면의 양보다는 수면의 질과 상관성이 있었으며 체성분, 영양소 섭취상태와도 상관성을 보였다. 생활 스트레스에 적절히 대처하는데 올바른 식습관 및 생활습관의 확립이 도움이 될 것으로 사료되며 대학생을 대상으로 운동, 자신이 좋아하는 취미활동 하기, 상담제도 이용 등의 올바른 생활스트레스 관리 방법에 대한 교육과 바람직한 식생활을 위한 영양교육이 필요하다고 사료된다. This study was performed in order to investigate the stress levels, sleep, anthropometric measurement and nutrient intakes their correlations of college students. General characteristics, stress scores using a stress test, sleep scores using a sleep test, anthropometric measurement, body composition using Inbody 3.0 and nutrient intakes using 3-day recalls were measured in 353 subjects (183 males and 170 females). Mean total stress score of the male students was 68.2${\pm}$45.0 and that of the female students was 86.5${\pm}$48.7. Stress for study, future, economic and value-related factors were higher than other factors in both male and female students. Female students were more stressed than male in friend, family, study, future and value-related factors. Mean sleeping time and sleep scores of the male students were 7.0 hrs and 40.6${\pm}$5.7, respectively and that of the female students were 7.1 hrs and 41.5${\pm}$5.3, respectively. Mean height, weight, percent body fat (PBF) and waist-hip ratio (WHR) of the male students were 174.8 cm, 73.3 kg, 19.0% and 0.84, respectively. Mean height, weight, PBF, and WHR of the female students were 161.7 cm, 55.3 kg, 28.7% and 0.81, respectively. Mean energy and protein intakes of the male students were 2026.3 kcal (77.9% EER) and 83.0 g (150.9% RI) and those of the female students were 1538.2 kcal (73.2% EER) and 60.7 g (134.9% RI), respectively. In male students, sleep duration, professor and future problem showed significantly negative correlation (p<0.05). For both male and female students, in correlations between sleep scores, life stress experience frequency and importance, the total scores showed significantly negative correlation (p<0.01). Sleep scores (sleep quality) have more significant correlation than sleep duration in life stress. In male students, correlations between economic problem and weight, waist circumference and hip circumference showed significantly negative correlation. In female students, correlations between different gender problem and body mass index (p<0.05), PBF (p<0.01), WHR (p<0.01) and obesity degree (p<0.05) showed significantly negative correlation while correlation between study problem and PBF (p<0.05), WHR (p<0.05) showed significantly positive correlation. In male students, there were significantly positive correlations between life stress experience frequency and carbohydrate calcium, iron, vitamin A; correlation between importance and calcium, iron as well as correlation between total life stress scores and iron (p<0.05). In female students, correlation between life stress experience frequency and thiamin along with correlation between importance and thiamin showed significant negative correlation (p<0.05). College students need to practice good life habits for the purpose of correctly managing life stress.

여자 대학생의 식생활 실천 지침과 체성분에 관한 연구

정희정,장경자,Chung Hee-Chung,Chang Kyung-Ja 동아시아식생활학회 2006 동아시아식생활학회지 Vol.16 No.3

To study the correlation between body composition values and practice of the Standard Guideline for Korean Dietary Life, a nationwide cross-sectional survey was conducted with 378 female college students living in four Korean cities in December 2005. Among the student subjects, 98 were analyzed for body fat mass, percent body fat, waist-hip ratio(WHR), body mass index(BMI) and obesity degree using Inbody 3.0(Biospace Co, Seoul, Korea). Percent body fat was at a high level of 54.1 %, WHR was at a high level of 58.2% and BMI was at a high level of 41.8%. However, both weight and body fat were below normal at 79.5% and 77.6%, respectively. Percent body fat, WHR, and BMI were slightly negatively correlated with vegetable consumption, but slightly positively correlated with beer intake. WHR > 0.8 was significantly negatively correlated with exercise. Standard Guideline for Korean Dietary Life was practiced to and above normal level by 64.6% of the female college students. However, female college students who are within the normal range of body composition value should notice that obesity will relate to abdominal or visceral fat on their body.

노인환자에서 Digoxin의 약동학적 매개변수 변화

박창선(Chang Sun Park),배성미(Seong Mee Bae),양성희(Seong Hee Yang),황보신이(Shinn Hwangbo),홍경자(Kyung Ja Hong),장춘곤(Choon Gon Jang),이석용(Seok Yong Lee) 대한약학회 2002 약학회지 Vol.46 No.1

The elderly patients are the most frequent users of digoxin because of increased prevalence of the two primary indications for digoxin therapy; atrial fibrillation (AF) and congestive heart failure (CHF). This study was Performed to observe a variation in digoxin pharmacokinetic parameters in advancing age and changing kidney function, and to compare the measured clearance with the calculated clearance. The 123 drug monitoring records of inpatients who had achieved steady state concentration of digoxin at a tertiary hospital from April 1999 to October 2001 were reviewed. In advancing age, measured digoxin clearance, volume of distribution and creatinine clearance were reduced. Compared with the calculated digoxin clearance, the measured digoxin clearance was more reduced in patients without CHF Especial1y: in elderly patents without CHF the measured digoxin clearance was lower than the calculated digoxin clearance. In contrast to non-CHF patients the measured value was greater than the calculated value in all CHF patients. Findings from this study indicate that the calculated digoxin clearance in elderly patients without CHF substantially overestimated the true clearance. Thus, it appears that the use of calculated digoxin clearance to estimate serum digoxin concentration may result in underestimation of the true serum concentration in a number of elderly patients without CHF.