A Correlation Analysis of Serum Creatinine Based eGFR and Serum Cystatin C Based eGFR with Thyroid Dysfunction Patients

임구,박형두,성호중,Lim, Gu,Park, Hyung-Doo,Sung, Ho Joong Korean Society for Clinical Laboratory Science 2017 대한임상검사과학회지(KJCLS) Vol.49 No.3

Serum creatinine-based eGFR and serum cystatin C-based eGFR are the most popular methods for measuring renal function. Thyroid hormone is known to affect serum creatinine-based eGFR and serum cystatin C-based eGFR; however, the clinical significance of thyroid dysfunctional patients of renal function evaluation has not been fully elucidated to date. This study examined the effect of thyroid hormone on serum creatinine-based eGFR and serum cystatin C-based eGFR. Moreover, we also evaluated the correlation analysis between serum creatinine-based eGFR and serum cystatin C-based eGFR in patients with thyroid dysfunction. A total of 442 patients with hypothyroidism and 284 patients with hyperthyroidism were investigated. A correlation analysis between thyroid hormone and serum creatinine- (and cystatin C-) based eGFR was performed. A correlation analysis between thyroid hormone and serum cystatin-C based eGFR indicated that serum cystatin-C based eGFR is more of an independent biomarker than serum creatinine-based eGFR in thyroid dysfunction patients. Therefore, serum cystatin C-based eGFR more accurately reflects renal function than serum creatinine-based eGFR in thyroid dysfunction patients.

세단 승용차량 트렁크용 휠체어 수납 시스템에 관한 연구

임구,김영재,김연옥,양순용 사단법인 유공압건설기계학회 2019 드라이브·컨트롤 Vol.16 No.3

Wheelchair users experience difficulty when using transportation. This is because wheelchair users must use transportation means together with wheelchairs. Therefore, in this paper, we developed a wheelchair storage system for passenger's car trunk. The mechanism is designed to allow a wheelchair and the device to be housed simultaneously in the narrow space of the trunk of the sedan passenger car. Additionally, this wheelchair storage system has implemented an initial load reduction mechanism that can mechanically reduce the initial load. This wheelchair storage system verified the system's operability through the production of the prototype. This system was actually installed in the trunk of the sedan passenger's car to verify the storage process. The operation and storage process of the wheelchair storage system was been perfectly verified. This wheelchair storage system will help a lot of self-driver or an assistant (female or elderly) who use wheelchairs.

양성돌발성두위현훈에서 일 년 재발률과 연관된 예후인자

임구일 대한이비인후과학회 2014 대한이비인후과학회지 두경부외과학 Vol.57 No.5

Background and Objectives Although benign paroxysmal positional vertigo (BPPV) was treated with particle repositioning maneuver (PRM) with a high success rate, the condition often recurred. The purpose of this study was to evaluate the variables for one year recurrence of BPPV recurrence. Subjects and Method Retrospective review was performed for 295 patients diagnosed as BPPV visiting clinic between February 2010 and June 2012. All patients underwent a complete otolaryngologic, audiologic, and neurologic evaluation. The appropriate PRM was performed, depending on the type of BPPV. Patients who received treatment were classified into two groups according to recurrence: a no recurrence group (n=240) and a recurrence group (n=55). Optimal independent variables were determined by using logistic regression analysis with forward stepwise selection. Binary logistic regression analyses were adjusted for age, sex, day of symptoms, associated ear disease, involved ear, type of otolith, affected canal and visit of treatment sessions. Results Average follow up time was 12 months. The recurrence rate was 18.6%. Two variables had a statistically significant impact on one year recurrence. The number of visits for treatment sessions was higher in the recurrence group than in the no recurrence group (mean±standard deviation=3.67±2.49 versus 2.44±1.55, p<0.001). The other variable was age being above 40 years (p=0.037). Age above 40 years was an independent variable for the one-year recurrence. Patient sex, day of symptoms, associated ear disease, involved ear, type of otolith and affected canal had no statistically significant impact. Conclusion Our data suggested that the number of visit for treatment sessions and age above 40 years were variables associated with the one-year recurrence of BPPV. Korean J Otorhinolaryngol-Head Neck Surg 2014;57(5):314-9

의료법인의 자법인 설립 이슈 : 의료법인의 자법인 도입 경과 및 추진 방안

임구일 한국보건행정학회 2014 한국보건행정학회 토론집 Vol.2014 No.1

Serum Vitamin D and Long-term Outcomes of Benign Paroxysmal Positional Vertigo

임구일 대한이비인후과학회 2019 Clinical and Experimental Otorhinolaryngology Vol.12 No.3

Objectives. The purpose of the present study was to examine the effect of serum vitamin D concentrations on the long-term recurrence rates of benign paroxysmal positional vertigo (BPPV) patients. Methods. The present study was conducted with patients diagnosed with BPPV from June 2014 to April 2016. Whether the patients’ sex, age, types and locations of semicircular canals, diabetes, hypertension, hyperlipidemia, and vitamin D concentrations affect their recurrence rates was examined using Pearson chi-square tests, independent samples t-tests and Cox proportional hazards regression analyses. The effects of vitamin D concentrations on long-term recurrence rates were examined using Kaplan-Meier estimates and log-rank tests. Results. The recurrence rates obtained with Kaplan-Meier estimates were 18% and 50% at 12 months and 24 months, respectively. When the patients were divided into groups with vitamin D concentrations of <10 ng/mL and ≥10 ng/mL and the recurrence rates of the groups were compared, the difference was statistically significant (P=0.040). In addition, when the patients were divided into groups with vitamin D concentrations of <15 ng/mL and ≥15 ng/mL and the recurrence rates of the groups were compared, the difference was statistically quite significant (P=0.017). In a Cox regression model, variables such as age, sex, the types and locations of semicircular canals, hypertension, diabetes, hyperlipidemia, and 25-hydroxy vitamin D did not significantly affect recurrence. Conclusion. The present study investigated the recurrence rates of BPPV in patients for a long time without limiting the sex, age, or locations of semicircular canals and it could be seen that serum vitamin D concentrations significantly affected the recurrence of BPPV.

양성 돌발성 두위현훈의 치료 후 장기추적 연구: Kaplan-Meier 생존분석

임구일 대한평형의학회 2016 Research in Vestibular Science Vol.15 No.1

Objective: The objective of this study is to determine the long-term recurrence rate of benign paroxysmal positional vertigo (BPPV) and the factors associated to such recurrence.Methods: Retrospective review was performed for 295 patients diagnosed as idiopathic BPPV. After successful resolution by particle repositioning maneuver, all patients were followed up by visiting clinic or telephone. A study period was 1–56 months and average follow up period for study population after the initial treatment was 26 months. The rate of recurrence was estimated according to the method of Kaplan-Meier and compared by the log-rank test. Results: Overall recurrence rate by Kaplan-Meier estimate was 50% at 30 months. Kaplan-Meier estimate suggests the effect of patient age, sex and visit of treatment sessions in initial episode on BPPV recurrence over 3 year follow-up period. Recurrent rate was significantly higher in patients aged 40 years or older (p<0.013) and in patients with three or more visit of treatment sessions (p<0.015). However, there was no significant association between recurrence rate and sex.Conclusion: The long-term recurrence of BPPV was associated with age above 40 years and the number of visit for treatment sessions. This finding suggests that the recurrence of BPPV may be related with aging process.Res Vestib Sci 2016;15(1):17-21

MALDI(Matrix-Assisted Laser Desorption/Ionization) 질량분석법

임구일,최영식 한국광학회 2005 광학과 기술 Vol.9 No.1

코로나 판데믹 이후의 이비인후과 진료환경의 변화 (개원가를 중심으로)

임구일 대한의사협회 의료정책연구소 2021 의료정책포럼 Vol.19 No.1

기관 캐뉼 발거 곤란증

봉정표,임구일,유기원,이준규,박성원,홍기수 대한기관식도과학회 1998 大韓氣管食道科學會誌 Vol.4 No.2

Background and Objectives : Decannulation failure may result from factors such as inadequate ability 0 clear secretion, mucosal induration, granulation tissue, restenosis, tracheal wall depression and vocal cord palsy. We were to evaluate the effectiveness of surgical treatment on the basis of site and type of stenosis. Materials and Method : A series of 44 cases of decannulation difficulty between 1993 and 1997 were reviewed. The following data were collected on each of these patients : primary disease, indication for tracheostomy, site of stenosis, endoscopic findings of stenosis, surgical techniques used for treatment. Results : Primary diseases were 30 head trauma, 4 neck injury, 10 other diseases. Indication for tracheostomy were 37 prolonged intubation, 4 emergency tracheostomy, 3 laryngeal trauma. Endoscopic findings of stenosis were 24 granulation tissue, 16 laryngotracheal collapse, 4 combined with granulation tissue and collapse. Site of stenosis were 3 glottic, 9 subglottic, 24 stomal, 1 substomal, 7 mixed. 22 of 24 cases were decannulation using endoscopic treatment. Conclusion : The most common cause of failed decannulation was sternal granulation tissue. The most effective treatment of granulation tissue was endoscopic technique.

일가족 내에서 발생한 Melnick-Fraser증후군

봉정표,이준규,임구일,김성수 대한이비인후과학회 1999 대한이비인후과학회지 두경부외과학 Vol.42 No.3