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구척 분획물의 성장기 흰쥐 장골 길이 성장에 대한 효과
임강현 ( Im Gang Hyeon ),김명규 ( Kim Myeong Gyu ),김호현 ( Kim Ho Hyeon ),박선영 ( Park Seon Yeong ),이동환 ( Lee Dong Hwan ),부영민 ( Bu Yeong Min ),김호철 ( Kim Ho Cheol ) 대한본초학회 2003 大韓本草學會誌 Vol.18 No.3
목적: 狗育의 성장촉진효과는 이미 보고된바 있다. 본 실험은 狗育추출물을 핵산층, 클로로포름층, 에칠아세테이트층, 부탄올층 및 물층의로 분리하여 어느 분획의 성장촉진효과가 가장 뛰어난지를 연구하기위해 구상되었다. 방법: 장골 길이성장에 대한 효과를 측정하기 위하여 테트라사이클린을 이용한 형광염색법과 성장관 높이 및 성장관 내 연골세포 증식도를 측정하였다. 결과 : 실험결과 핵산층 투여군에서 유의한 골성장억제를 관찰할 수 있었고, 클로로포름층 및 부탄올층 투여군에선 모두 골성장이 유의하게 증가되었다. 결론 : 狗育에서 청소년기 골 길이성장을 조절하고 촉진시키는 작용을 가질 것으로 생각되어지는 성분은 클로로포름층 및 부탄올층에 함유되어있을 것으로 예상되며 핵산층의 경우는 성장을 억제하는 성분을 함유하고 있을 것으로 생각된다. N/A
성장관련 한약 혼합제제의 흰쥐 장골 길이성장에 대한 효과
임강현 ( Im Gang Hyeon ),김호현 ( Kim Ho Hyeon ) 대한본초학회 2003 大韓本草學會誌 Vol.18 No.3
N/A Objectives : This study was designed to investigate the effects of herbal composition on the growth of longitudinal bone in the adolescent male rats. Methods : Longitudinal bone growth was measured by fluorescence microscopy after injection of tetracycline, which formed fluorescent band to the bone forming sites. To examine the effects on the growth plate metabolism, the heights of growth plate was measured. Results : Treatment of herbal composition (200 mg/kg 및 500 mg/kg) significantly enhanced longitudinal bone growth compared with control group. And herbal composition promoted the height of growth plate. Conclusion : Herbal composition enhanced longitudinal bone growth and promoted the height of growth plate in adolescence male rats .
강순아 ( Kang Sun A ),장기효 ( Jang Gi Hyo ),박성규 ( Park Seong Gyu ),임종필 ( Im Jong Pil ),전훈 ( Jeon Hun ),최훈 ( Choe Hun ),임강현 ( Im Gang Hyeon ) 대한본초학회 2003 大韓本草學會誌 Vol.18 No.4
N/A Objectives : This study was designed to investigate the effects of herbal composition on obese rats induced by high fat diet(@% of calories). Methods : Body weight, fat mass, and serum cholesterol were measured to find out the activity of herbal composition. Serum AST and ALT were tested to check the toxicity as well. Results : Treatment of herbal composition significantly decreased the weight gain and epididymal fat mass compared to control group. Serum total cholesterol level was significantly reduced by herbal containing diet. Also, herbal composition promoted the ratio of HDL cholesterol and total cholesterol. Conclusion : Results of this study showed that herbal composition might reduce body weight, body fat mass and improve the lipid composition in the obese rats fed high fat diet.