지하도로 수요제어 및 차로변경 허용 전략에 따른 운영 효과 평가 - 신월여의지하도로를 중심으로 -

이진각,박상현,고상운 한국도로학회 2024 한국도로학회논문집 Vol.26 No.2

PURPOSES : This study sought ways to connect urban above ground roads and underground roads to utilize urban space more efficiently in the development of underground roads, which are currently under development in order to alleviate problems caused by oversaturated above-ground roads. A simulation analysis was performed to develop an operation strategy that connects above-ground and underground roads to prevent congestion in above-ground areas such as entrances and exits from transferring to underground roads as well as to present its effectiveness. METHODS : Traffic efficiency analysis according to the operation strategy of above ground and underground roads was conducted using VISSIM, a microscopic traffic simulation software. The functions implemented in VISSIM were collected to set effectiveness analysis indicators for each underground road operation strategy. The Shinwol-Yeoui Underground Road was selected as the spatial scope of this study, and a surrounding road network was constructed. In addition, full-scale simulation analysis preparations were completed by performing network calibration based on the actual traffic attribute data of underground and surrounding surface roads within the construction scope. Accordingly, a traffic efficiency evaluation analysis was conducted based on the underground road operation strategy. CONCLUSIONS : Information on the increase in traffic volume within the Shinwol-Yeoui underpass was collected every 15 min. The analysis was divided into an analysis of the traffic situation within the underpass through demand control when the service level reached level D and an analysis of when demand control was not performed. It was found that demand control was necessary for the Shinwol-Yeoui Underpass when the internal traffic volume reached 2,500 vehicles/h. In addition, to analyze the spread of traffic and congestion owing to the weaving phenomenon caused by lane changes in the underpass, an analysis was conducted to observe the traffic improvement effect when full lane changes are possible for the Shinwol-Yeoui Underground Road, which currently has some lane-change-permitted sections. The analysis showed that both the maximum traffic volume and average travel speed showed better results when lane changes were allowed, and the communication situation at Yeoui JCT was found optimal.

Link & Place 개념을 반영한 도로의 기능 및 용도지역 특성 적용성 검토

이진각,손영태,한상진,Lee, Jin-Kak,Son, Young-Tae,Han, Sang-Jin 대한교통학회 2010 교통 기술과 정책 Vol.7 No.2

경제성 분석을 위한 자전거 도로가치 평가 연구

이진각,이상화,손영태 한국도로학회 2006 한국도로학회 학술대회 발표논문 초록집 Vol.2006 No.10

도로 노면 안전성 분석을 위한 물고임 측정장비 개발 및 현장 적용성 연구

이진각,윤덕근,조영오 한국도로학회 2013 한국도로학회논문집 Vol.15 No.3

PURPOSES : The purpose of this study is development of automatic equipment to measure the road water-reservoir which can be one of factors for road traffic safety inspection and its application to safety analysis. METHODS : The scopes of this study are the examination of the riskiness and location of road water-reservoir through literature review,development of appropriate sensor and automatic equipment to survey the road water-reservoir and evaluation of field application. RESULTS: The laser lighting and IR camera were selected to develop the equipment. It was found from the field calibration that there is a high correlation between rutting and road water-reservoir and road water-reservoir caused by rutting can be correctly calculated. About 20.2km of national highway were inspected for case study and field application. It was found from correlation of traffic incident that 2.08km of the latent length for water-reservoir which is related to 12 traffic incidents were analyzed. CONCLUSIONS : This technique can be utilized evaluation method for road condition such as road water-reservoir for conventional evaluation system such as road traffic safety assessment and safety analysis and it can be use to new evaluation system to apply various road condition and traffic condition.

A Novel Computational Method for Biomedical Binary Data Analysis: Development of a Thyroid Disease Index Using a Brute-Force Search with MLR Analysis

이진각,한원석,이준석,윤창노 대한화학회 2017 Bulletin of the Korean Chemical Society Vol.38 No.12

The thyroid disease index (TDI), which estimates thyroid disease progress based on hormone concentration measurements and hormone pattern changes, was developed. In this study, we measured concentrations of hormone profiles in the androgen and estrogen metabolic pathways from 23 patients with thyroid disease, as well as 20 unaffected people. We illustrated that the hormones 2-hydroxyestrone (2-OH-E1), 2-hydroxyestradiol (2-OH-E2), 2-methoxyestrone (2-MeO-E1), 2-methoxyestradiol (2-MeO-E2), and 2-methoxyestradiol-3-methylether (2-MeO-E2-3-methylether) are related to the development of thyroid disease through t-tests. Though the concentration levels of these hormones generally increase as the disease progresses, big fluctuations cause the determining of a disease's progress by measuring hormone levels to be difficult. The differing patterns between the correlation matrices of the disease and control groups possibly indicates changes in hormone releasing patterns during the thyroid disease's progress. Because of a lack of progressive experimental data on thyroid disease, binary data for the two categories (the thyroid disease patients and the control group) was utilized. Binary logistic regression was used to analyze five risk factors associated with thyroid disease, and the highest overall accuracy was 97.7% with three risk factors. Logistic regression models, however, are unable to describe disease progress. Hence, the TDI was developed to estimate thyroid disease progress. An arbitrary ranking of disease progress was generated for the TDI equation. The ranking contained a total number of 29 030 400 entries with six stages from the control group and eight stages from the disease group. Multiple linear regression (MLR) analysis was performed with a brute-force search. The best result among the MLR runs presented strong correlation (r2 values of 0.840 and q2 values of 0.663) between the selected hormones and the values of the disease progress in the training set. Overall accuracy of our novel method was 90.7%, which is worse than the 97.7% of logistic regression models. Brute-force search with MLR analysis might classify different types of thyroid disease progress such as thyroid mass (0.8055), goiter (0.8806), thyroid mass which was a thyroid cancer before operation (0.8951 and 0.9112), and cancer (1.001–2.144). The results show that the TDI is a good indicator of thyroid disease progress and that brute-force search with MLR analysis is useful for biomedical binary data analysis.

Grey System Theory를 이용한 차량 및 보행환경 통합평가

이진각,손영태,한상진,박진영,이상화 대한교통학회 2010 大韓交通學會誌 Vol.28 No.4

In this paper, understanding there is a limitation with a comprehensive and network approach for the evaluation of existing vehicle and pedestrian environments, the authors focus on developing an integrated approach to assessing these environments. The network evaluation here means the assessment at a three- dimensional level that includes evaluation methods of lines/axes in a spatial concept as well as integration of evaluation indicators being used for vehicles and the walking environment. Grey System Theory (GST) was applied based on the theoretical background for network and comprehensive integrated evaluation, and the evaluation of the vehicle and pedestrian environment was performed by assigning target areas to walking preference zones. As a result of the comprehensive evaluation and analysis by GST, even if the service level is the same as the operating indicators (Highway Capacity Manual) of the vehicle and pedestrian environment, or relatively better, it was identified that the total score could be varied over Grey Category because the observed data are calculated after considering the weights between evaluation indicators by the range of Grey Category on the comprehensive evaluation. Considering comprehensively these points, although the indicators on the operation of roads are relatively good, in the event that the indicators on the safety of roads are bad, it was known that the scores over Grey Category also could be changed. The result is that this evaluation method can be used to evaluate the network concept per lane (per axis) as well as to diagnose the current state by type of urban street in the future. 본 연구에서는 기존의 차량 및 보행환경의 평가에 있어서 종합적이고 통합적인 접근방식에 한계가 있다고 진단하고, 이를 고려하는 평가 방법 개발에 중점을 두었다. 여기에서의 통합적인 평가라 함은 차량환경과 보행환경에서 쓰이고 있는 수단별 평가지표에 대한 통합과 더불어, 공간적 개념에서 선/축의 평가방식을 포함한 면적인 차원의 평가라 할 수 있겠다. 본 연구에서는 통합 평가를 위한 이론적 배경으로 Grey System Theory(GST)를 적용하였으며, 대상지역은 보행우선구역 시범사업지로 하여 차량 및 보행환경에 대한 평가를 수행하였다. GST에 의한 종합평가 및 분석결과, 같은 서비스 수준 또는 상대적으로 차량 및 보행환경의 운영지표상(도로용량편람)에서는 보다 양호한 상태라 할지라도 관측된 데이터가 Grey Category 범위에 따라 통합평가 시에는 평가지표간 가중치 등이 고려되어 산정되었기에 Category 상에서의 종합점수는 달라지는 것을 알 수 있었다. 이러한 점을 종합적으로 고려해 볼 때, 도로운영상의 지표들이 상대적으로 좋다고 하더라도 안전상의 지표들이 나쁠 경우에는 그에 따라 Grey Category상의 점수들도 변화하는 것을 알 수 있었으며, 본 평가 방법을 통해 향후 도시가로 형태별로 현재 상태를 진단할 뿐 아니라 노선별(축별), 면적인 개념에서의 평가와 더불어 평가지표간 통합평가가 이루어 질 것으로 기대하고 있다.

신약개발을 위한 타겟단백질의 구조계산

이진각,한원석,윤창노 한국산업미생물학회 2002 생물산업 Vol.15 No.3

운전자 시야를 고려한 사각 교차로의 교차각 평가에 관한 연구

이진각,손영태 명지대학교 산업기술연구소 2001 産業技術硏究所論文集 Vol.20 No.-

Sight distance in a skewed intersection that provides sight hindrance to a driver is conceptualized in this research. In addition, this paper developed a method of available sight distance incorporating visual angle of a driver which varies by driver's pose and by vehicle types. Also, minimum intersection sight distance, the value of A.S.D is obtained by the developed formula. Design velocity for a main road and stopping sight distance in accordance with intersection angle are obtained by using the maximum acceleration performance and response time for a vehicle in a sub road to cross a main road. In conclusion, when a passenger car is analyzed as design vehicle, proper intersection angle is at least over 65 degree and is at least over 70 degree for semi-trailer or large car.

β1,6-GlcNAc Linkage to the Core Glycan on TIMP-1 Affects Its Gelatinase Inhibitory Activities: Aberrantly Glycosylated TIMP-1-MMP2 Complex Modeling Shows Weaker Interaction Compared to Bi-antennary Glycosylated TIMP-1

이진각,한원석,이준석,김용삼,고정헌,유종신,윤창노 대한화학회 2017 Bulletin of the Korean Chemical Society Vol.38 No.3

Matrix metalloproteinases (MMPs) are proteolytic enzymes that can regulate the tumor microenvironment. Metalloproteinase-1 (TIMP-1) is a MMP inhibitor that plays a critical role in the invasion and migration of cancer cells. N-acetylglucosaminyltransferase-V (GnT-V) catalyzes the attachment of a β1,6-N-acetylglucosamine (GlcNAc) linkage to the core glycan, and TIMP-1 has identified target proteins for GnT-V. Recent research reveals that aberrantly glycosylated TIMP-1 showed a weaker inhibition on gelatinase, and that this aberrancy of glycosylation was closely related with cancer cell invasion and metastasis. However, the mechanism of action of glycan modification is not known at the molecular level. In this study, the bi-antennary and aberrant glycan structures were determined by mass spectrometry, and a model of the glycosylated TIMP-1-MMP2 complex was constructed to study the effects of glycosylation on the inhibitory activity of TIMP-1. Then this model was used to examine the effects of attaching a β1,6-GlcNAc linkage to the core glycan on the interaction of TIMP-1 with MMP2. The gelatinase inhibitory activity is decreased when additional a β1,6-GlcNAc moiety is linked to the core glycan on TIMP-1. The modeled structure of the glycosylated TIMP-1-MMP2 complex reveals how aberrant N-linked glycan hinders the interaction of these molecules.

VR 모의주행 시뮬레이터를 활용한 도심 지하도로 내 운전자 주행행태 분석

이진각,박상현,고상운 한국도로학회 2022 한국도로학회지 Vol.24 No.2