http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : 이장규(JangKyuLee) (검색결과 3 건)
- 무료
- 기관 내 무료
- 유료
-
운동생리학 : 규칙적인 운동이 Type Ⅱ 근섬유 내 지질대사 관련 유전자 및 PPAR 단백질의 발현과 효소 활성도에 미치는 영향
박수연(SooYeonPark),이종삼(JongSamLee),이장규(JangKyuLee),조인호(InHoCho),김창근(ChangKeunKim) 한국체육학회 2004 한국체육학회지 Vol.43 No.3
We investigated whether regular exercise exerts any significant roles in regulatory genes (i.e., fatty acid translocase [FAT/CD36] mRNA, carnitine palmitoyl transferase [CPT]-1 mRNA β-hydroxyacyl CoA dehydrogenase [β-HAD] mRNA, pyruvate dehydrogenase kinase-4 [PDK4] mRNA, mitochondrial uncoupling protein-3 [UCP3] mRNA) and proteins (peroxisome proliferators-activated receptor [PPAR] α and ν ) expression and enzyme (citrate synthase [CS] and [β-HAD]) activities that closely involved in lipid uptake and oxidation in skeletal muscle cells. Sixteen female Sprague-Dawley rats were used, and divided into two experimental conditions: either untrained (n=8) or trained (n=8). While rats in untrained group performed no training, animals in trained group undertook 8wk of regular exercise (4 times wk-1, 1000m session-1) on the treadmill. The expression of all genes important for lipid oxidation tended to increase in trained group but statistical significance was only found in PDK4 (p〈0.01) and UCP3 (p〈0.05). Despite increases in the expression of some of genes involved in lipid metabolism there was no effect of chronic exercise on PPARα and ν protein abundance in extensor digitorum longs (EDL) muscle (p>0.05). Similar to PPAR protein expressions, oxidative enzymes were not shown any significant effect following 8w k regular exercise program. This study suggested that activation of PPAR α and ν may not be necessary for the coordinated induction of fatty acid oxidative genes after chronically trained muscle. Additional studies examining the exercise duration and intensities of this molecular response, the major transcriptional regulators, and gene expressions should be undertaken.
-
운동생리학 : 수영이 MCAO 유발 후 뇌허혈 및 하지의 근위축에 미치는 영향
이정필(JeongPilLee),김호성(HoSeongKim),김영주(YoungJuKim),신영오(YoungOhShin),이장규(JangKyuLee),오재근(JaeKeunOh) 한국체육학회 2004 한국체육학회지 Vol.43 No.4
This study was undertaken to determine the improving effects of swimming training on brain ischemic lesions and muscle atrophies caused by middle cerebral artery (MCA) occlusion in male rats. Rats were divided into four groups: MS(MCAO plus swim), MC(MCAO plus control), SS(Sham plus swim), SC(Sham plus control). From 4d after induction, MS and SS rats were participated in swimming exercise during 30min. Rats were sacrificed 24h after last treatment and brain slices were prepared for TTC stained to assess lesion size, and also TA muscle were prepared for histochemical analysis. The infarct volumes of MS were significantly decreased than MC. The wet weights and relative wet weights to body weights of paretic side in MS were significantly heavier than MC. The relative wet weights to body weights in SC were significantly heavier than MC whereas no significantly differences between MS and SS. Increased percentages of type I and decreased percentages of type IIb were denoted in paretic sides than healthy sides of MS. The CSAs of type I in paretic sides of MS were significantly larger than MC and than healthy sides. These finding suggest that earlier started swimming training can prevent increasing infarct volume and improve muscle atrophy of TA induced MCAO.
-
운동생리학 : 장시간의 운동이 노화에 따른 쥐 근육 내 pro- 및 macro-glycogen 동운에 미치는 영향
어수주(SuJuEo),이종삼(JongSamLee),조인호(InHoCho),표재환(JaeHwanPyo),박수연(SooYeonPark),김효식(HyoSikKim),이장규(JangKyuLee),김창근(ChangKeunKim) 한국체육학회 2005 한국체육학회지 Vol.44 No.5
The purpose of this study was to examine that the effect of one single bout of prolonged exercise on pro- and macro-glycogen mobilization in aging rat skeletal muscle. Forty eight rats were used and divided into three groups by age; 0 week (n=16), 16 weeks (n=16), 32 weeks (n=16). Each experimental group was further divided into two subgroups; either control (n=8) or exercise (n=8). All animals in exercise groups performed one bout of 3hr swimming exercise (30min × 6bouts). One week before the animals were sacrificed, oral glucose tolerance test (OGTT; 2 grams of glucoseㆍkg<sup>-1</sup> of body mass) was undertaken. At pre-determined time points, the animals were anesthetized by inhalation of ether, and red vastus lateralis muscle was rapidly dissected out and used for total glycogen content as well as pro- and macro-glycogen content measurement. Body mass was significantly heavier in 16wk (302.0±11.1 g) and 32wk (325.7±10.1 g) compared to 0wk (117.8±0.9g), but it was not statistically different between 16wk and 32wk. Three hours of swimming exercise significantly lowered plasma glucose concentration in all experimental groups (p<.001). Resting insulin concentration was only significantly different between 0wk and 32wk (not 16 wk). In aspects of serum insulin concentration, it was the highest in 32wk, and was the lowest in 0wk after 3hr swim exercise. Although resting total glycogen concentration was not significantly different among experimental groups, proglycogen concentration was significantly increased and macroglycogen concentration was significantly decreased in aged muscle. Although 3hr of swim exercise significantly lowered muscle PG content, MG level was not significantly altered. In summary, as aging process continued, PG concentration was increased and the degree of mobilization was continuously increased. This implies that PG may play a major role for energy production during prolonged exercise in aged rat skeletal muscles.
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
