소음인(少陰人) 태음병(太陰病) 심하비증(心下?證)의 병증약리(病證藥理) 고찰

서영광,이지원,이준희,최원철,이의주,고병희,Seo, Young-Kwang,Lee, Ji-Won,Lee, Jun-Hee,Choi, Won-Cheol,Lee, Eui-Ju,Kho, Byung-Hee 사상체질의학회 2010 사상체질의학회지 Vol.22 No.3

1. Objective: Gastric Stuffiness (心下?證) in the Soeumin Taeeum symptomatology (少陰人 太陰病) in Sasang Constitutional Medicine shows an interesting evolutionary process. Originally found in the texts of Sanghanlun (傷寒論), the perspectives regarding the symptoms of Gastric Stuffiness were expanded by many medical scholars and Lee Jema. To comprehend the Jema's concept of Taeeum symptomatology and utilize his prescription clinically, it deserves to study on the Gastric Stuffiness in Donguisuseowon (東醫壽世保元). 2. Methods: Many texts including Sanghanlun (傷寒論) and Dongeuibogam (東醫寶鑑) were reviewed in order to track the evolutionary process concerning the symptoms of Gastric Stuffiness. Also, Lee Jema's works including the different versions of Donguisuseowon (東醫壽世保元) were reviewed to examine the development of Lee's concepts regarding the Gastric Stuffiness in the Soeumin Taeeum symptomatology. 3. Results and Conclusions: 1) Most of the previous concepts on Gastric Stuffiness were generally similar to those found in Sanghanlun, especially in that they addressed Yang deficiency of the middle triple energizeer as the central pathogenic process. 2) Lee Jema's views on the epigastric discomfort in the Soeumin Taeeum symptomatology evoloved over time and culminated in the finalized pathology and therapeutics appearing in his last work, the Shinchuk version of Donguisuseowon (東醫壽世保元). 3) 4 kinds of prescription which invented by Lee Jema to treat the Gastric Stuffiness in the Soeumin Taeeum symptomatology can be matched to the prescription of Sanghanlun respectively. However through evolutionary process of Jema's prescriptions, the indication of them expanded: not only to treat Gastric Stuffiness but to diverse symptoms of Soeumin.

저령차전자탕(猪苓車前子湯)의 기원(基源), 변천과정(變遷過程) 및 구조원리(構成原理)

권오원,김배수,이지원,신승원,이의주,Kwon, Oh-Won,Kim, Bae-Su,Lee, Ji-Won,Shin, Seung-Won,Lee, Eui-Ju 사상체질의학회 2016 사상체질의학회지 Vol.28 No.2

Objectives This paper investigates the origin, the progressive changes and the constructive principles of Jeoryoungchajeonja-tang(猪苓車前子湯).Methods Jeoryoungchajeonja-tang and other related prescriptions were analyzed in terms of their pathological indications, based on previous literature including 『Sanghannon(傷寒論)』, 『Keumkuaeyoryak(金匱要略)』, 『Donguibogam(東醫寶鑑)』, 『Donguisusebowon‧Sasangchobongwon(東醫壽世保元‧四象草本卷)』, 『Donguisusebowon‧Gabogubon(東醫壽世保元‧甲午舊本)』, 『Donguisusebowon‧Sinchukbon(東醫壽世保元‧辛丑本)』Results and Conclusions 1) The origin of Jeoryoungchajeonja-tang is discovered in the prescriptions for Lee-su(利水), that is, Jeoryoung-tang(猪苓湯). 2) Ohryoung-san(五苓散) introduced in 『Donguisusebowon‧Sasangchobongwon(東醫壽世保元‧四象草本卷)』progressively transformed into Shihosaryoung-san(柴胡四苓散)(『Donguisusebowon‧Gabogubon(東醫壽世保元 ‧甲午舊本)』) and ultimately into Jeoryoungchajeonja-tang(『Donguisusebowon‧Sinchukbon(東醫壽世保元‧辛丑本)』), a prescription appropriate for usage in the Mangeum symptomatology(亡陰證). 3) The Jeoryoungchajeonja-tang is composed of 10 herbs. Of these, Notopterygium incisum Ting(羌活), Aralia cordata Thunb.(獨活), Schizonepeta tenuifolia Briq.(荊芥), Saposhnikovia divaricata Schischk.(防風) make the Pyoeum(表陰) drop, and Anemarrhena asphodeloides Bge.(知母), Gypsum fibrosum(石膏) scatter the uihwa(胃火), and Poria cocos Wolf.(茯苓), Alisma canaliculatum(澤瀉), Polyporus umbellatus Fr.(猪苓), Plantago asiatica L.(車前子) facilitate urination.

심경부주(心經附註)의 사상(思想)과 이제마(李濟馬) 사상(思想)과의 비교

김인태,이의주,고병희,Kim, In-tae,Lee, Eui-ju,Koh, Byung-Hee 사상체질의학회 1997 사상체질의학회지 Vol.9 No.2

심경부주(心經附註)의 고찰(考察)과 심경부주(心經附註)에서 나타나고 있는 사상(思想)과 이제마(李濟馬)의 사상(思想)과의 비교에서 다음과 같은 결론을 얻었다. 1. 모든 사람의 마음에는 두 가지의 마음이 존재한다. 이는 심경(心經)에서는 인심(人心)과 도심(道心)으로, 이제마(李濟馬)는 군자지심(君子之心)과 소인지심(小人之心)으로 표현하였다. 2. 심경부주(心經附註)에서는 인심(人心)과 도심(道心)은 성인(聖人)과 중인(衆人)을 구별시키는 중요한 요점이 되는데 성인(聖人)의 경우는 이 두 마음을 잘 분별하여 도심(道心)으로 인심(人心)이 인욕(人欲)에 빠지는 것을 경계하는 사람이라 하였다. 이제마(李濟馬)의 경우에서는 군자지심(君子之心)은 역지(易知)이고 소인지심(小人之心)은 난지(難知)라 하고 군자지심(君子之心)이 많은 사람은 군자(君子)이고 소인지심(小人之心)이 많은 사람은 소인(小人)이 된다고 하였다. 3. 이러한 군자(君子)의 경지에 오르기 위해 심경(心經)과 이제마(李濟馬)는 여러 가지 수행 방법을 제시하는데 공통적으로 계신공구(戒愼恐懼)를 말하고 심경(心經)에서는 이러한 계신공구(戒愼恐懼)를 위해서는 경(敬)이 가장 우선이 된다고 하고, 이제마(李濟馬)는 여인상접지성(與人相接之性)과 자기독득지성(自己獨得之性)을 들어서 절불절(節不節), 중불중(中不中)과 지인(知人), 지천(知天)을 말하고 있다. 4. 계신공구(戒愼恐懼)를 통하여 성의(誠意)를 이루고 이것으로 정심(正心)을 하는 것을 심경(心經)은 말하는데 이제마(李濟馬)는 지인(知人)을 통한 치심정기(治心正己)를 말하고 있다. 5. 맹자(孟子)의 사단(四端)은 성(性)을 이루는 중요한 마음의 단초가 되니 확충(擴充)을 해나가야 하는 것이 된다. 이제마(李濟馬)는 격치고(格致藁)에서 이러한 사단(四端)의 사심신물(事心身物)로 분화된 모습을 말하고 이를 동의수세보원(東醫壽世保元)에서는 천인성명(天人性命)으로 표현을 하면서 각각의 심욕(心欲)과 각각의 선(善)한 부분을 말하고 있다. By the investigation of "Sim-Kyoung-Bu-Ju" and the comparison study between the thought of "Sim-Kyoung-Bu-Ju" and that of Lee Je-ma, I've got the following conclusion. 1. All man have two mind. That is explained that "In-Sim" and "Do-Sim" in the "Sim-Kyong-Bu-Ju", "Kun-Ja-Ji-Sim" and "So-In-Ji-Sim" in the Lee Je-ma. 2. says that "In-Sim" and "Do-Sim" are the important point of the distinguishment of the "Sung-In" from "Jung-In". The "Sung-In" is the man who distinguishes "In-Sim" from "Do-Sim" well, and he always is cautious for "In-Sim"s" falling in desire by the "Do-Sim". In the case of LeeJe-ma,"Kun-Ja-Ji-Sim" is easy to know and "So-In-Ji-Sim" is hard to know. The man of "Kun-Ja-Ji-Sim" being large part is "Kun-Ja" and the man of "So-In-Ji-Sim" being large part is "So-In". 3. To reach the state of the "Kun-Ja", the "Sim-Kyoung-Bu-Ju" and Lee Je-ma present the variant training methods, "Kei-Shin-Kong-Ku" which they have in common. The "Sin-Kyoung-Bu-Ju" presents the "Kyung" firstly for "Kei-Shin-Kong-Ku", Lee Je-ma presents the "Yo-In-Sang-Jep-Ji-Sung" and "Ja-Ki-Tok-Tuk-Ji-Sung" for "Jel-Bu-Jel", "Jung-Bu-Jung", "Ji-In", "Ji-Chen". 4. The "Sim-Kyoung-Bu-Ju" says that establish the "Sung-Ui" by the "Kei-Shin-Kong-Ku", and to "Jung-Sim" by the "Sung-Ui", Lee Je-ma says "Chi-Sim-Jung-Ki" by "Ji-In".

세종시 노인복지시설 기초조사

이의주(Lee, Eui-Ju),변나향(Byun, Na-Hyang) 한국주거학회 2023 한국주거학회 학술대회논문집 Vol.35 No.1

The purpose of the study was to examine the supply of welfare facilities in new towns through the facility location and to discuss the demand for facility planning in the areas where future residential complexes are built. Distribution of elderly welfare facilities is examined, focusing on leisure welfare facilities and elderly home care including day careda based on the criteria classified under the Elderly Welfare Act. As a result of the survey, the distribution pattern was organized by comparing the planned area in Sejong City with other areas. The results of this paper will be used as pilot study to local facility planning for living support of elderly.

HFP가 첨가된 수소/공기 혼합기의 자연점화에서의 화학반응

이의주(Lee, Eui-Ju),오창보(Oh, Chang-Bo) 한국화재소방학회 2008 한국화재소방학회 학술대회 논문집 Vol.2008 No.춘계

Autoignition suppression of hydrogen/air premixed mixtures by <TEX>$CF_3CHFCF_3$</TEX>(HFP) was investigated computationally. Numerical simulation was performed in isobaric and homogeneous system to evaluate the induction times. The detailed chemistry of 93 species and 817 reaction mechanism was introduced for hydrogen/air/HFP mixtures. The results shows the similar concentrations for the major reactants such as hydrogen and oxygen during autoignition while water vapor produced at the ignition temperature was decomposed later, which leaded to the shoulder on the concentration of H, OH and O radical with time. The fluorine included from HFP was converted mainly to stable HF and the carbon was formed to various species, CF2, CF2O, CO etc. More details of chemical effects of HFP addition will be investigate with sensitivity analysis in the near future.

미국인용 체질진단지에 의한 체질별 응답차이에 따른 문항 분석:Pilot test

이의주,유정희,Lee, Eui-Ju,Yoo, Jung-Hee 사상체질의학회 2009 사상체질의학회지 Vol.21 No.1

1. Purpose This study has focused on response rates of the questionnaire which considered as a basic data to identify constitution for American. 2. Methods By analysing the tendency of the respondents who has defined constitution by clinical diagnosis and comparing of their answers, the result of their constitution analysis by our questionnaire were re-examed. The answer of each question to each constitution were tested how it is relevent to a scale of a constitution. Each item response rate on SF_SSCQ-A was analysed about those who had been tested and diagnosed as Taeyangin, Soyangin, Taeeumin, Soeumin respectively. 3. Results There were the 55 significant items; 13 Taeyangin items, 13 Soyangin items, 20 Taeeumin items, 9 Soeumin items. However, there were the 11 low response rate items (below 10 %) and 4 no response items.

WSR 초기수트 조건에서의 입자 크기, 농도 및 화학적 특성

이의주(Eui Ju Lee),George. W. Mulholland 대한기계학회 2004 대한기계학회 춘추학술대회 Vol.2004 No.4

The characteristics of soot near the soot inception point for an ethene-air flame was carried out in a WSR (well-stirred reactor). The new sampling tool like the temperature controlled filter system was introduced to minimize the condensation during sampling. The new analysis tools applied include the real time size distribution analysis with the Nano-DMA, particle size by transmission electron microscopy, C/H analysis, g filter analysis, and thermogravimetric analysis using both non-oxidative and oxidative pyrolysis. The WSR can generate young soot particles that can be collected and examined to gain insight into inception. For the current conditions, soot does not form for Φ=1.9, inception occurs at or before Φ=2.0, and inception combined with soot surface growth and/or coagulation occurs for Φ=2.1. The filter samples for Φ=1.9 are composed of volatile compounds that evolve at relatively low temperatures when heated in the presence or absence of O₂. The samples collected from the WSR at Φ=2.0 and Φ=2.1 are precursor-like in morphology and size. They have higher C/H ratios and lower organic percentages than precursor particles, but they are clearly not fully carbonized soot. The WSR PAH distribution is similar to that in young soot from inverse flames.

결핵균의 유전자 분석법으로 증명된 가족 내 결핵 전파

박의주 ( Eui Ju Park ),김양기 ( Yang Ki Kim ),복진현 ( Jin Hyun Bok ),이영목 ( Young Mok Lee ),김기업 ( Ki Up Kim ),어수택 ( Soo Taek Uh ),박영길 ( Young Kil Park ) 대한결핵 및 호흡기학회 2008 Tuberculosis and Respiratory Diseases Vol.65 No.6

결핵균은 공기를 매개로 전파되고 결핵균에 노출된 시간과 최초의 노출 정도가 전파의 위험을 증가 시키는 중요한 인자로 알려져 있다. 활동성 폐결핵 환자와 함께 생활하는 가족 내에서 감염이 현저히 증가하는데 이는 결핵균에 노출되는 기회 및 시간이 증가하기 때문이다. 하지만 고식적인 접촉자 조사만으로는 흔히 결핵 발생률을 과소평가할 수 있기 때문에 접촉자 조사와 결핵균의 유전형 조사를 병행하는 것이 감염의 위험이 높은 집단을 선별해내고 발생빈도 및 전염경로를 밝히는 데 보다 효과적인 것으로 보고되고 있다. 이에 접촉자 조사와 결핵균의 유전형 조사를 통해 가족 내 결핵균 전파를 증명한 1예를 보고하는 바이다. (Tuberc Respir Dis 2008;65:512-516)

Child class C의 조기 간세포암 환자와 Child class A의 진행성 간세포암 환자에서의 생존 비교

박의주 ( Eui Ju Park ),장재영 ( Jae Young Jang ),정승원 ( Soung Won Jeong ),추진우 ( Jin Woo Choo ),김진녕 ( Jin Nyoung Kim ),권순하 ( Soon Ha Kwon ),이병무 ( Byoung Moo Lee ),이세환 ( Sae Hwan Lee ),김상균 ( Sang Gyune Kim ),차 대한간암학회 2013 대한간암학회지 Vol.13 No.2

Background/Aims: The prognosis of hepatocellular carcinoma (HCC) is affected by stage as well as liver function. We analyzed the survival outcome of early stage HCC in Child class C patients and advanced HCC in Child class A patients. Methods: Among 453 HCC patients with good performance status Group A included 33 consecutive Child class C patients with early stage (I II) HCC and Group B included 45 consecutive Child class A patients with advanced stage (III IV) HCC. We investigated the clinical characteristics cirrhotic complications and prognostic factors related with survival in each group and compared overall survival between two groups. Results: Age prothrombin time total bilirubin and Model for End-Stage Liver Disease (MELD) scores were significantly higher in Group A. Male sex platelet count albumin sodium (Na) hepatitis B virus alpha fetoprotein (AFP) and portal vein thrombosis were significantly higher in Group B. Complications of cirrhosis such as variceal bleeding ascites and hepatic encephalopathy were increased in Group A (P<0.05). Patients with an elevated AFP (>400 ng/mL) tended to exhibit poor survival as it increased in Group A (P=0.084). MELD scores>15 (Hazard ratio[HR] 17.84 95% confidence interval [CI] 3.70-85.93 P<0.001) stage IV (HR:3.27, 95% CI 1.10-9.75 P=0.033) and absence of HCC treatment (HR: 3.70 95% CI 1.06-12.50, P=0.040) were independent poor prognostic factors in Group B. Median overall survival was 24.6 months (95% CI 10.6-38.4) for Group A and 13.5 months (95% CI 4.6-22.3) for Group B (P=0.278). In the HCC treatment group there were no significant differences of median overall survival between Group A and Group B respectively (27.1 vs. 15.7 months P=0.338). In patients with conservative treatment Group A and Group B had a significantly different median overall survival of 13.6 and 2.5 months respectively (P=0.012). In patients of Group B median overall survival was significantly higher in patients who received treatment of HCC compared to those who did not respectively (15.7 vs. 2.5 months P<0.001). Conclusions: Overall median survival was not different between both groups. However in Child class A patients with advanced stage HCCs the cumulative median survival was higher in patients who received treatment of HCC compared to those who did not. Therefore advanced stage HCC patients with good liver function should be considered for HCC treatments.

한국인 신체분절에 관한 사상의학적 연구

이의주,이재구,김정연,송정모,Lee, Eui-ju,Lee, Jae-koo,Kim, Jeong-yun,Song, Jeong-mo 사상체질의학회 1998 사상체질의학회지 Vol.10 No.1

연구목적 한국인 성인남녀를 대상으로한 신체분절에 관한 사상의학적 연구이다. 생체를 8-10분절로 분획하고 인체계측 및 침수법(Immersion Method) 및 평형측정판법(Reaction Board Method)을 이용하여 각 신체분절의 생체역학적 특성을 사상체질별로 객관화한다. 연구대상 연구대상자는 한국인 성인으로 남자 49명 여자 23명으로 총72명이며, 평균연령은 $29.4{\pm}8.54$세이고 태음인 30명, 소양인 17명, 소음인 25명이었다. 연구방법 인체계측항목중 신체분절길이 및 둘레와 골폭 및 스킨폴드 두께는 Lohman 등(1988)의 인체계측 부위 및 방법에 따라 42개 항목과 사초부위의 9항목으로 총 51개 항목을 측정하였다. 사지의 측정은 우측을 선택하였다. 침수법에 의하여 부피를 측정하고 밀도공식에 의하여 질량을 산출하였고, 평형측정판법에 의하여 무게중심을 구하였다. 연구결과 1. 인체계측항목에서 살펴보면 남자의 경우 둘레에서 체질별로 유의한 차이가 있었다. 2. 체적에서 살펴보면 남자의 경우 태음인과 소음인에서 유의한 차이가 있었고, 특히 두경부, 손, 발의 경우 태음인이 가장 작은 비율을 나타냈고 소음인이 가장 컸다. 3. 무게중심은 남자의 경우 소양인이 다른체질에 비하여 위에 있었다. PURPOSE This studied the biomechanical body segment parameters of Korean adults with reference to Sasang Constitutional Medicine(SCM). We anlyzed the characteristics of Sasang constitution through Body Measurement, Immersion Method, and Reaction Board Method. SUBJECT Subjects were 72 persons. There were made 49 and Female 23. Mean age was . And There were Taeumin 30, Soyangin 17, and Soeumin 25. METHOD The items of Body Measurement were 51. Limbs were measured right side. Volume was gained with Immersion Method and Weight was calculated with the density equation for limbs from Drills and Contini. Center of Mass was gained with Reaction Board Method. RESULT 1. In Body Measurement there were the significant differences with each constitution of man's circumference. 2. In Volume there were the significant differences between Taeumin and Soeumin in mand. And the volume rate of head and neck, hand, and foot was the lowest in Taeumin, but the highest in Soeumin. 3. In center of mass Soyangin was higher than others.