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방광의 침윤성 암종을 닮은 방사선에 의한 상피세포 증식 -2예 보고-
이옥준,김규래,엄대운,김현정,명나혜,노재윤 대한병리학회 2004 Journal of Pathology and Translational Medicine Vol.38 No.5
Radiation-induced epithelial proliferation in the urinary bladder mimicking urothelial carcinoma has received only a little attention in the literature. Herein, we describe two cases of radiation-induced epithelial proliferative changes, which mimicked invasive urothelial carcinoma. Cystoscopy revealed bullous or edematous mucosal changes with multiple hemorrhagic foci. Microscopically, we observed inverted epithelial proliferation, forming nests and cords extending into the lamina propria. The epithelial cells in these nests and cords exhibited enlarged, hyperchromatic and pleomorphic nuclei, closely mimicking the infiltrative growth of urothelial carcinoma. However, the presence of radiation-induced changes was validated by the observation of abundant vacuolated cytoplasm, normal or slightly increased nuclear to cytoplasmic ratios, the absence of mitotic activity, dilated blood vessels containing frequent fibrin thrombi, scattered atypical fibroblasts, and the patients' previous history of radiation treatment. Radiation-induced changes should be always included in differential diagnoses of proliferative epithelial lesions in the urinary bladder and a pertinent clinical history of radiotherapy should be searched.
이옥준,조영미,이향임,한덕종,노재윤 대한병리학회 2004 Journal of Pathology and Translational Medicine Vol.38 No.5
Mixed ductal-endocrine carcinoma of the pancreas is composed of ductal and endocrine carcinoma components and each component makes up a significant proportion in the primary tumor as well as in the tumor of metastatic sites. Mixed ductal-endocrine pancreatic carcinoma is exceptionally rare and, to our knowledge, only five cases have been reported in the literature. Recently we experienced a case of mixed ductal-endocrine pancreatic carcinoma with regional lymph node and hepatic metastases in a 63-year-old woman. Here, we report a case of mixed ductal-endocrine pancreatic carcinoma with a review of the literature.
이옥준,피윤성,조현서,조경자,김상윤,노재윤 대한병리학회 2004 Journal of Pathology and Translational Medicine Vol.38 No.4
Dermatofibrosarcoma protuberans (DFSP) typically presents during the early or mid-adult life, and the most common site of origin is the skin on the trunk and proximal extremities. DFSP of the parotid gland is extremely rare and only one case has been reported in the literature. We present here a case of a 30-year-old woman with DFSP occurring in the parotid gland, and we discuss the differential diagnosis. The patient is alive and doing well one year after her operation.
이건국,최영석,이옥준 충북대학교 의과대학 충북대학교 의학연구소 1997 忠北醫大學術誌 Vol.7 No.1
갑상설관낭은 두경부에 생기는 가장 흔한 낭이나 갑상설관낭에서 발생하는 악성 종앙은 매우 드문 질환으로, 갑상설관낭의 약 1% 미만에서 발생한다. 현재까지 100여예가 보고 되었으며 국내에 오직 몇예만 보고되었다. 43세 여자의 갑상설관낭에서 발생한 원발성 유두상 암종 1예를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. This report presents a case of papillary thyroid carcinoma arising in a thyroglossal duct cyst(TGDC) of a 43 year-old women and literature is reviewed. Thyroglossal duct cyst is a common congenital cyst, occuring in the neck and carcinomas arising in the TGDC are a rare event. To date, approximately 100 cases of carcinoma have been reported, the majority of them being papillary carcinoma. Only a few cases have reported in Korea.