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- 저자 : 이아룸 (검색결과 3 건)
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이해혁,김태희,박준식,이아룸,박용순,변동원,김민정,임희숙 대한폐경학회 2014 대한폐경학회지 Vol.20 No.3
To see the effect of dietary administration of omega 3-fatty acid formula on the vaginal cells of postmenopausal rats. Methods: Three-week-old female Wistar/ST rats were raised after one week of adjustment period. The rats were then dividedinto three groups, for three different kinds of diet; general diet, 1% omega-3 fatty acid diet, and 2% omega-3 fatty acid diet. Aftereight weeks of having assigned diet, after the oophorectomy, with the same diet previously they had Immunohistochemistry,Immunofluorescence, and Western Blot about ezrin, merlin were done. Results: In immunohistochemistry, estrogen injection group revealed thicker and well differentiated features. In Immunofluorescence,Omega-3 fatty acid composition in diet did not effect expression of ezrin and merlin in rat vagina in estrogeninjection group, their vaginal epithelium showed full layers (from basal to apical layer). In Western Blot analysis, Omega-3 fatty acidcomposition in diet did not affect expression of ezrin and merlin in rat vagina estrogen presented significant impact on expressionof ezrin and merlin. Conclusion: Although omega-3 fatty acid composition changed in diet, vaginal epithelial morphology unchanged. Estrogen dideffect on vagina cell, but omega-3 fatty acid did not effect on ezrin and merlin in vagina. (J Menopausal Med 2014;20:97-103)
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Premenstrual Syndrome and Premenstrual Dysphoric Disorder in Perimenopausal Women
정수호,김태희,이해혁,이아룸,전동수,박준식,김예솔 대한폐경학회 2014 대한폐경학회지 Vol.20 No.2
To evaluate the prevalence of premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD) of perimenopausal women at a university hospital along with their menstrual characters.Methods: A questionnaire survey regarding premenstrual symptoms was carried out in 100 perimenopausal women (43 to 53, years). The pattern of menstruation and, the intensity of dysmenorrhea were assessed; and further, the symptoms were classified according to their number, intensity, and persistence. The PMS criteria of American College of Obstetrics and Gynecology (ACOG) and PMDD criteria by American Psychiatric Association (APA) were evaluated. Results: The approximate prevalence of PMS criteria was 95% and that of PMDD criteria was 23%. The most dominant symptoms were ‘breast tenderness’, ‘abdominal bloating’, ‘and headache’. PMDD was significantly associated with the severity of dysmenorrhea (P = 0.020). There was no significant relation with age, height, weight, body mass index and the cycle of menstruation. Conclusion: Most women experience PMS and PMDD, which and have a significant impact on the activity of perimenopause women. However in most women that do not know well about PMS and PMDD. We should educate and inform women of PMS and PMDD, thus helping them increase their quality of life. (J Menopausal Med 2014;20:69-74)
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Sclerosing Stromal Tumor in an Elderly Postmenopausal Woman
김태희,이해혁,홍정아,박준식,전동수,이아룸,고은석 대한폐경학회 2014 대한폐경학회지 Vol.20 No.2
Sclerosing stromal tumor (SST) of the ovary is a rare tumor derived from the sex cord stroma. This tumor was first described by Chalvaridjian and Scully in 1973. SST of the ovary is prevalence of 1.5% to 6% of ovarian stromal tumors. Patients are most commonly diagnosed in their 20s and 30s. There have been reports of SST postmenopausal women aged 65-, 67-, and 71 in the Republic of Korea; however, no report of this disease has been reported in women older than 80. In this study, we would like to report an 80-year-old postmenopausal woman who did not previously complain of any symptoms, and was finally diagnosed with SST. She was involved in a traffic accident, and huge pelvic mass was found during the evaluation of intra-abdominal hemorrhage. Total abdominal hysterectomy with bilateral salpingo-oophorectomy was performed ; a final pathologic diagnosis reported SST. (J Menopausal Med 2014;20:80-83)
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