후두 결핵의 후두 내시경 소견과 임상 양상 분석

이상혁,이승석,이노희,반재호,이경철,진성민,Lee, Sang-Hyuk,Lee, Seung-Suk,Lee, No-Hee,Ban, Jae-Ho,Lee, Kyung-Chul,Jin, Sung-Min 대한후두음성언어의학회 2006 대한후두음성언어의학회지 Vol.17 No.1

Background and Objectives: There has been a gradual decline in the incidence of laryngeal tuberculosis due to effective an-tituberculous chemotherapy and improvement in the standard of living. During the last decade, however, the disease has changed its clinical pattern. We aimed to study a clinical and telescopic evaluation of laryngeal tuberculosis. Materials and Method: A retrospective clinical analysis was done for 16 patients who diagnosed laryngeal tuberculosis from January 2000 through December 2004. All patients had a complete clinical and laboratory work-up including telescopy, chest X-rays, sputum cultures, Tbc PCR(polymerase chain reaction). Laryngeal biopsies were performed in some cases. All the patients received proper antituberculous chemotherapy. Results: The patients age ranged from 21 to 59 with a mean age 43. The male to female ratio was 10:6. The prominent presenting symptom was hoarseness. The various telescopic findings were categorized: 7 patients showed ulcerative, 4 patients granulomatous, 3 patients ulcerofungative, 2 patients had nonspecific inflammatory lesions. Involving sites were true vocal cord most commonly in 12 patients. Three of 16 patients had normal chest X-ray fmding. Among 16 patients, 4 patients showed positive response for AFB stain, 13 patients showed positive for Tbc PCR. Biopsy was done for 3 patients who were not confirmed in initial tuberculous test. All patients responded satisfactorily to antituberculous medication. Conclusion: The telescopic findings and clinical manifestations of laryngeal tuberculosis have changed and seemed to be different from those of classic reports. Thus, the clinicians who deal with the various symptoms and diseases should be aware of the existence of laryngeal tuberculosis and the changing patterns of the disease.

학술 3 - 동물등록제에서 동물병원의 역할

이상혁,Lee, Sang-Hyeok 대한수의사회 2013 대한수의사회지 Vol.49 No.3

육군 전자식 기술교범 표준 S/W 개발 및 운용에 관한 연구

이상혁,오세준,Lee, Sang-Hyeok,O, Se-Jun 한국방위산업진흥회 2003 國防과 技術 Vol.- No.297

최근의 국내.외에서는 정보의 보관 및 활용측면에서 CALS의 일환인 전자식 기술교범에 관한 개발이 활발하게 이루어지고 있다. 이미 국내에서도 K9 자주포에서 기술교범을 개발하여 운용중에 있으며, 해.공군에서도 전자식 기술교범을 개발 중 혹은 계획중에 있는 실정이다. 그러나 이러한 전자식 기술교범 구축을 위해 필요한 소프트웨어는 해외 도구를 활용중이거나 국내의 업체에서 개발된 표준화되지 않은 소프트웨어를 활용하고 있는 실정이다. 이에 따라 전자식 기술교범 개발비 상승, 상호 활용성 미확보, 기술교범 국방규격서 충족의 어려움 등 여러 가지 문제점을 내포하고 있다. 따라서 이러한 문제점을 해결하기 위해 국내의 육군 지상무기체계 전자식 기술교범 개발시 공통으로 적용이 가능한 표준 소프트웨어를 개발하게 되었다. 이 글에서는 이렇게 개발된 육군 전자식 기술교범 표준 소프트웨어(,KAIS : Korean Army IETM Software)에 대해 기술하고자 한다.

공황장애 약물 치료에 대한 한국형 알고리듬 개발(3) - 인지행동치료 -

이상혁,양종철,윤세창,서호석,김찬형,유범희,김민숙,Lee, Sang-Hyuk,Yang, Jong-Chul,Yoon, Se-Chang,Suh, Ho-Suk,Kim, Chan-Hyung,Yu, Bum-Hee,Park, Min-Sook 대한불안의학회 2008 대한불안의학회지 Vol.4 No.1

Objective : A working group of psychiatrists from the Korean Academy of Anxiety Disorders was established to determine the appropriate medication algorithm for treating patients with panic disorder. In this article, we discussed the consensus among psychiatrists regarding the use of cognitive behavior therapy (CBT) in the development of a treatment algorithm for panic disorder in Korea. Methods : Based on the guidelines or algorithms published by the American Psychiatric Association, National Institute for Clinical Excellence, and Canadian Psychiatric Association, we constructed questionnaires regarding the core components and contents of CBT for patients with panic disorder. Fifty-four experts in panic disorder completed the questionnaires. Results : There was statistically significant consensus among the experts in the belief that cognitive reconstruction and psychological education are the core components of CBT for the treatment of patients with panic disorder. However, there was some inconsistency between the opinions of some experts regarding the content and frequency of CBT and the results of studies published outside of Korea. Conclusions : CBT, especially the psychological education and cognitive reconstruction components, should be considered when treating patients with panic disorder. However, further consideration needs to be put into the design of a more detailed treatment guideline for the use of CBT in the treatment of patients with panic disorder.

인공습지 형태에 따른 비점오염저감효율 분석

이상혁,김이형,조혜진,Lee, Sang Hyuk,Kim, Lee Hyung,Cho, Hye Jin 응용생태공학회 2014 Ecology and resilient infrastructure Vol.1 No.2

비점오염저감시설에 대한 연구는 활발히 진행되고 있으나, 도로에 자연형 비점오염저감시설 설치시 비점오염저감효율에 대한 연구는 없는 실정이다. 본 연구에서는 도로에 설치된 여러 종류의 인공습지에 대한 비점오염 저감효율을 모니터링과 유량가중평균농도법을 이용하여 분석하였다. 분석결과, 인공습지는 일반적인 오염물질인 TSS, COD, BOD, TN, TP에 대한 저감효율은 비교적 우수한 것으로 나타났으며 중금속인 Cr, Zn, Pb의 제거효율은 낮거나 거의 없는 것으로 나타났다. Studies of non-point pollutant treatment facilities have widely been conducted for a decade, but natural non-point pollutant treatment facilities implemented on roads have not been carried out for the removal efficiency of non-point pollution sources. This study analyzed the removal efficiency of non-point pollution sources from constructed wetlands using monitoring and event mean concentration method. As a result of this study, removal efficiency of general non-point pollution sources as TSS, COD, BOD is relatively good, but removal efficiency of TN, TP, Cr, Zn, Pb is very small or nothing.

가스터빈 연소진동 데이터 처리를 위한 FFT 기반의 모니터링 시스템

이상혁,강필순,Lee, Sang-Hyeok,Kang, Feel-Soon 한국정보통신학회 2007 한국정보통신학회논문지 Vol.11 No.12

This paper presents a method for improvement of communication speed and reduction of data storage space in gas turbine monitoring system to acquire, save, and display combustion vibration data. The proposed method implements FFT from sampled raw data. The FFT result data are encoded to be transferred to monitoring PC for storage. By this way, it can reduce data storage space. To display the received data, it needs inverse FFT to reconstruct original signal. To verify the validity and efficiency of the proposed scheme, computer-aided simulation are carried out. It includes the analyzed results the relationship between FFT's order and Gibb's Phenomenon. Finally, high-performance of the proposed method is proved by combustion experiment results using a prototype gas turbine. 본 논문에서는 가스터빈의 연소진동 데이터의 취득, 저장, 표시를 위한 모니터링 시스템의 구현에 있어 통신 속도의 향상 및 데이터 저장 공간을 축소시킬 수 있는 방안을 제시한다. 제안된 방법은 샘플 원시 데이터(Raw Data)로 부터 FFT를 수행하고 결과 데이터를 코드화 하여 모니터링 PC로 전송하여 저장함으로서 데이터 저장 공간을 줄일 수 있다. 수신된 데이터를 화면에 표시하기 위한 원신호로의 복원은 역 FFT에 의해 이루어진다. 제안된 방식의 타당성과 효율성 검증을 위해 시뮬레이션을 수행하였으며, FFT 차수와 Gibbs's 효과간의 상관관계를 분석하였다. 모의 가스터빈의 연소실험을 통해 제안된 데이터 처리 및 저장 방법의 우수성을 검증하였다.

21세기 보병전투차량(IFV/ICV)의 발전 방향

이상혁,Lee, Sang-Hyeok 한국방위산업진흥회 1999 國防과 技術 Vol.- No.241

현대전은 군수면에서의 기술적 우세에 의해 전쟁의 승패가 결정된다는 걸프전의 교훈을 바탕으로, 주요 선진국들은 나름대로의 계획과 형편에 따라 주변기술의 발전과 더불어 21세기를 대비하는 보병전투차량의 연구.개발을 수행하고 있다. 이러한 주요 선진국들의 IFV/ICV의 발전 추세를 철저하게 분석하여, 우리 군의 현 실태와 앞으로의 나아갈 바를 판단할 수 있는 계기를 마련하고, 이에 적극적으로 대처하는 연구.개발 활동과 접근자세가 내부적으로 더욱 필요하다고 판단된다

신뢰성 있는 정보의 추출을 위한 퍼지집합의 유사측도 구성

이상혁,Lee Sang-Hyuk 한국통신학회 2005 韓國通信學會論文誌 Vol.30 No.9C

모호함의 측도를 위하여 퍼지 엔트로피와 거리측도 그리고 유사측도와의 관계를 이용하여 새로운 퍼지 측도를 제안하였다. 제안된 퍼지 엔트로피는 거리측도를 이용하여 구성된다. 거리측도는 일반적으로 사용되는 해밍 거리를 이용하였다. 또한 집합사이의 유사성을 측정하기 위한 유사측도를 거리 측도를 이용하여 구성하였고, 제안한 퍼지 엔트로피와 유사측도를 증명을 통하여 타당성을 확인하였다. We construct the fuzzy entropy for measuring of uncertainty with the help of relation between distance measure and similarity measure. Proposed fuzzy entropy is constructed through distance measure. In this study, the distance measure is used Hamming distance measure. Also for the measure of similarity between fuzzy sets or crisp sets, we construct similarity measure through distance measure, and the proposed 려zzy entropies and similarity measures are proved.

공황장애 치료에 대한 한국형 알고리듬 개발(1) - 배경, 조직구성, 알고리듬 개발의 원칙, 개발계획, 개발방법

이상혁,유범희,김찬형,윤세창,Lee, Sang-Hyuk,Yu, Bum-Hee,Kim, Chan-Hyung,Yoon, Se-Chang 대한불안의학회 2007 대한불안의학회지 Vol.3 No.2

In this special article, we presented the organization of the work group, basic principles of the algorithm, future plan and methods for developing a treatment algorithm for panic disorder in Korea. The psychiatrist work group from the Korean Association of Anxiety Disorders began to develop a treatment algorithm designed to improve the management of Korean patients with panic disorder by incorporating better evaluation techniques and treatment procedures. We have reviewed the treatment guidelines and algorithms for panic disorder published thus far, including the Practice Guideline for the Treatment of Patients with Panic Disorder established by the American Psychiatric Association, the Management of Anxiety (Panic Disorder, with or without Agoraphobia, and Generalized Anxiety Disorder) in Adults in Primary, Secondary and Community Care established by the National Institute for Clinical Excellence, and the Clinical Practice Guidelines established by the Canadian Psychiatric Association. We developed the basic materials to be used in the treatment algorithm for the management of panic disorder in Korea. Therefore, in this special article, we intro-duce the goal of the algorithm and the details of the algorithm development.

보툴리눔 독소의 약리

이상혁,이현섭,진성민,Lee, Sang Hyuk,Lee, Hyun Sub,Jin, Sung Min 대한후두음성언어의학회 2012 대한후두음성언어의학회지 Vol.23 No.2

Botulinum toxins are the most potent toxins known to mankind. Botulinum toxin acts by blocking the cholinergic neuromuscular or the cholinergic autonomic innervation of exocrine glands and smooth muscles. Seven distinct antigenic botulinum toxins (A, B, C, D, E, F and G) produced by different strains of Clostridium botulinum have been described and only A and B type of botulinum toxins were clinically used. Toxins were consisted of a heavy chain with a molecular weight of 100 kD and a light chain with a molecular weight of 50 kD. Toxins are bound with an astounding selectivity to glycoprotein structures located on the cholinergic nerve terminal. Subsequently light chain of toxin is internalized and cleaves different proteins of the acetylcholine transport protein cascade transporting the acetylcholine vesicle from the intracellular space into the synaptic cleft. After a decade of therapeutic application of the toxin, no anaphylaxis or deaths have been reported and systemic adverse effects have not been reported so far. However the toxin's immunologic properties can lead to the stimulation of antibody production, potentially rendering further treatments ineffective. Botulinum toxin is a safe and effective treatment. Use of botulinum toxin in clinical medicine has grown exponentially in recent years, and many parts of the human body are now being targeted for therapeutic purposes.