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        간장 ( 肝臟 ) , 담도 ( 膽道 ) 및 췌장 ( 膵臟 ) : 백서에서 담도폐색이 장내세균의 전위에 미치는 효과

        이상전(Sang Jeon Lee),김주섭(Joo Seop Kim) 대한소화기학회 1991 대한소화기학회지 Vol.23 No.3

        N/A This experiment was performed to determine whether absence of bile within the intestinal tract promotes enteric bacterial translocation. Two groups of rats were studied: sham operation (n=2O) and CBD-ligated (n=30). Ten days after the operation the rats were sacrificed and the livers, mesenteric lymph nodes and a portion of ileocecum were harvested for microbiology and histopathology. The results were as follows: 1) The bilirubin levels of the CBD-ligated group were much elevated than those of the sham operation group. 2) The incidence of translocation to mesenteric lymph nodes was significatnly higher in the CBD-ligated group than that of the sham operation group, but there was no difference between the two groups in magnitude of translocation per positive mesenteric lymph node. 3) The levels of G (-) enteric bacilli in the cecum in CBD-ligated group were significantly higher than those in sham operation group, and also significantly higher in translocated group than in non-translocated group. 4) The histopathology of the terminal ileum and mesenteric lymph nodes in most translocated group showed the appearance of ileitis and reactive hyperplasia respectively, suggesting destruction of the mucosal barrier and bacterial invasion of the lymph nodes. In conclusion, biliary obstruction allows enteric bacterial overgrowth and impairment of intestinal mucosal barrier which appears to promote bacterial translocation.

      • Chest PA 검사 시 피검자의 Effective Dose(유효선량)에 관한 고찰

        박상만(Sang Man Park),이상전(Sang Jeon Lee),안미섭(Mi Seop An),문희석(Hee Seok Moon),조남수(Nam Soo Cho) 대한영상의학기술학회 2009 대한영상의학기술학회 논문지 Vol.2009 No.-

        Purpose : When examining chest PA, to know whole body x-ray damage level exactly by measuring patients’ effective dose. Materials and methods : The experiment equipment is REVOLUTION XQI chest private x-ray machine of GE Company, Glass dosimeter (DOSE ACE [Asahi Technograju Company]) is used for measuring expose dose. The experimentway is to expose with the conditions FFD 180cm, 100kVp(HVL 4.08mmAl), 3.08mAs, Field Size 43cm*43cm, calculating air absorbing dose by inserting Glass dosimeter organ position endowed organ load coefficient named by ICRP inside ART(ANDERSON RADIATION THERAPHY) Phantom To indicate organ absorbing dose by air absorbing dose in each position multiplies organ and air mass suction coefficient, and then to know Effective Dose by multiplying each organ load coefficient. We found 1 expose effective dose by averaging total 10 times expose, and knew errors 5 times with doing the same process. Results : Examining the above, the average ESD was about 0.1116mGy (SD 4.89, CV 0.044), effective dose was about 29.8420Sv. Conclusion : During the chest PA, the effective dose of patients damaged is about 0.0298mSv, 5 times repetition result is SD 1.04, CV 0.03489.

      • KCI등재

        Quality of life changes during adjuvant chemotherapy in patients with colon cancer

        Seo Hee Lee(이서희),Taek-Gu Lee(이택구),Moo Jun Baek(백무준),Jang Jin Kim(김장진),Sung-Su Park(박성수),Sang-Jeon Lee(이상전) 대한종양외과학회 2016 Korean Journal of Clinical Oncology Vol.12 No.1

        Purpose: The survival of advanced colon cancer patients has increased due to the development of surgical techniques and adjuvant chemotherapy. The administration of adjuvant chemotherapy after curative resection is generally accepted as a standard of care. The primary endpoint of chemotherapy should include not only tumor response and survival, but also impact on the quality of life (QoL). We evaluated changes in QoL during adjuvant chemotherapy in patients with colon cancer. Methods: Between October 2009 and February 2012, 56 patients with stage II and III colon cancer received the combination adjuvant chemotherapy 5-flurouracil/folinic acid with oxaliplatin (FOLFOX). Patients were asked to complete the QoL questionnaire QLQ-C30 version 3 before and after 6 cycles of adjuvant chemotherapy. Results: There was no significant difference in the QoL between the start of chemotherapy and after the completion of 6 cycles. After completion of 6 cycles, global QoL was worse in patients >70 years of age. The functional scale score was low in patients with chemotherapy schedules delayed more than 2 times due to adverse events. Patients with body weight increases greater than 5% scored lower on symptom scales. Interestingly, patients with peripheral neuropathy scored higher on symptom scales. Conclusion: QoL changes during adjuvant chemotherapy did not show significant differences. After the sixth chemotherapy, QoL was affected by age, body weight gain, delay of the scheduled chemotherapy, and peripheral neuropathy. Therefore, the proper attitude of physicians focused on reassurance and education of patients is very important during chemotherapy.

      • 일본 여행사 브랜드 경쟁관계 평가 연구

        김상준(Kim, Sang-Jun),이상전(Lee, Sang-jeon) 대한경영학회 2012 대한경영학회 학술발표대회 발표논문집 Vol.2012 No.1

        본 연구는 일본의 여행사에 대한 개괄적인 지식을 제공하는 차원에서 진행되었다. 즉, 일본 여행사 중 취급순위를 기준으로 5개사를 선정하여 경쟁관계를 확인함으로서 향후 일본 여행사에 관한 경영, 마케팅 분야에 관한 연구를 진행함에 있어 필요한 정보 및 시사점을 제시하고자 하였다. 일본 여행사 브랜드 간의 경쟁관계를 분석하기 위하여 여행사 선택요인과 여행사 브랜드 자산 요인을 이용하였으며, 이론적 검토 및 선행연구를 통하여 여행사 선택요인과 여행사 브랜드 자산 평가 요인을 측정하기 위한 각각의 4개 측정변수를 도출하였다. 이러한 요인들을 이용하여 다차원척도법 등의 분석기법을 이용하여 현재의 경쟁상황을 파악하고 그 외 기초적인 분석 등을 실시하였다. 본 연구에서 분석의 대상이 되는 여행사는 일본에서 현재 운영중에 있는 일본 국토교통성 관광청에서 발표하는 여행업 관련 통계자료를 참조하여 선정하였다. 일본인 여행객들을 대상으로 이루어진 조사설문지는 최종적으로 배포된 480부 중 435부(회수률 90.6%)가 회수하여, 최종적으로 385부(응답률 80.2%)가 본 연구의 실증분석에 사용되었다. 분석결과에서는 여행사 선택 요인에 있어서는 JTB가 비교적 경쟁관계가 약한 것으로 나타났으며, 킨키 일본 투어리스트와 한큐교통사, 일본여행과 HIS가 유사성이 높은 것으로 나타나 높은 경쟁관계를 유지하고 있는 것으로 나타났다. 브랜드 자산 요인에서는 킨키 일본 투어리스트와 한큐교통사, 일본여행의 3개 여행사가 유사성이 높은 것으로 나타나 경쟁관계가 높은 것으로 나타났으며, JTB와 HIS가 각각 유사성이 낮은 것으로 나타나 경쟁관계가 약한 것으로 나타났다. 그러나 본 연구에서는 보다 구체적인 일본 여행사들의 특성과 마케팅 전략의 차이, 일본 고객들의 여행사 이용 특성 등 다양한 시사점을 제시하지 못하는 한계가 있어 추가 연구를 통해 이러한 한계점을 보충하고자 한다. This research was advanced for the purpose of offering the general-condition information to a Japanese tour company. That is, it is that the information presentation needed when doing research on the future management and the marketing field of Japan to a tour company, and an indicator are shown by checking the rivalry of a Japanese tour company. In order to analyze the rivalry between the brands of a tour company, we decided to use a tour company selection factor and a tour company brand property factor, and four measurement variables of both factors were drawn through examination and the previous work of theoretical research after that. In addition, while utilizing the analysis technique of multidimensional scaling and having grasped the present competition situation, other fundamental analysis was also parallel. Selection of the travel firm which is the analysis target of this research chose top five companies on the basis of main travel agents" amount of travel handling announced from the Japan Tourism Agency of Japan. The investigation question paper carried out for the Japanese tourist distributed 480 copies, and 435 copies (90.6% of recovery rate) were collected in it. Eventually, 385 copies (80.2% of response rate) were used for the positive analysis of this research. As for an analysis result, in a tour company selection factor, rivalry is weakly expressed in JTB [Japan Travel Bureau] comparison, It became clear that it is a competitive advantage compared with the other company, Kinki Nippon Tourist Co., Ltd., Hankyu Travel International Co., Ltd., Nippon Travel Agency Co., Ltd., and H.I.S. Co., Ltd. were shown that it is similar, and the result of being in high rivalry came out of them. It was shown by the brand property factor that Kinki Nippon Tourist Co., Ltd., Hankyu Travel International Co., Ltd., and three companies of Nippon Travel Agency Co., Ltd. had high similarity, and the result that similarity was shown low and therefore JTB [Japan Travel Bureau] and H.I.S. Co., Ltd. had weak rivalry was shown. However, there would be a limit in presentation completely and I would like to make problems, such as the characteristic of the tour company in more concrete Japan, a difference in a marketing strategy, a customer"s tour company use characteristic, in to a future research task in this research.

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