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이상영 ( Sang Young Yi ),조동희 ( Dong Hui Cho ),황승하 ( Seung Ha Hwang ),오경환 ( Kyung Hwan Oh ),김현정 ( Hyeon Jeong Kim ),김지훈 ( Ji Hun Kim ),김명환 ( Myung-hwan Kim ) 대한췌담도학회 2016 대한췌담도학회지 Vol.21 No.3
IgG4-SC는 type 1 AIP의 가장 흔한 췌장 외 발현으로 type1 AIP 환자의 약 70%에서 발생하는 것으로 보고되었고 드물게 단독으로 발생하기도 한다. IgG4-SC의 진단은 임상적으로 매우 중요한데, 이는 영상 소견상 담관암과의 감별이 어렵기 때문이다. IgG4-SC의 경우, 스테로이드 투여로 회복될수 있다는 점에서 그 의의가 크다. 이번 증례 보고에서 저자들은 증상이 경미하고 영상 검사에서 IgG4-SC를 충분히 의심할만한 환자에서 조직검사 및 스테로이드 투여를 통해 담관암으로 확진된 증례를 경험하였기에 확진을 위한 생검의 중요성을 다시 강조하면서 문헌고찰과 함께 보고하는 바이다. IgG4-related sclerosing cholangitis (IgG4-SC) represents a rare but clinically challenging differential diagnosis in patients with biliary strictures which can be mistaken for cholangiocarcinoma. We present a case of a 73-year-old male presented with abdominal discomfort and weight loss. Biliary images showed long-segment luminal narrowing of extrahepatic bile duct associated with prominent enhanced wall thickening, but luminal patency was preserved. Pancreatic images revealed segmental irregular narrowing of main pancreatic duct without upstream duct dilatation. His liver function tests and CA19-9 level were normal. Putting all findings together, IgG4-SC associated with autoimmune pancreatitis was strongly suspected. However, endobiliary biopsy of extrahepatic bile duct revealed adenocarcinoma which was not resectable due to celiac axis involvement. Because there is an overlap in biliary imaging findings between IgG4-SC and cholangiocarcinoma, biopsy is essential for adequate differential diagnosis. We present a case of cholangiocarcinoma masquerading as IgG4-SC based on clinical and imaging findings. Korean J Pancreas Biliary Tract 2016;21(3):168-173
이종형 ( Jong-hyung Lee ),이상영 ( Sang-young Lee ),이창헌 ( Chang-heon Yi ),김윤곤 ( Yun-gon Kim ),임춘규 ( Chun-kyoo Lim ),이춘곤 ( Chun-kon Lee ),권영신 ( Yung-shin Kwon ) 한국산업융합학회 2007 한국산업융합학회 논문집 Vol.10 No.3
Prediction of fatigue duration is attainable from the analysis of the growth rate of the fatigue crack, and the property of the fatigue crack growth is determined by the calculation of the stress intensity factor. And the evaluation of the stress intensity factor, K comes from the stress analysis of the vicinity of crack tip of the continuum. This study describes a simple method to decide the stress intensity factor for the small crack at the sharp edge notches. The proposed method is based on the similarities between elastic stress fields of the notch tip described by two parameters, the stress concentration factor K, the radius of arc of the notch . And it is applicable to the analysis of the semi-elliptical penetration cracks and the edge notches.
이종형(Jong-Hyung Lee),이상영(Sang-Young Lee),이창헌(Chang-Heon Yi),김윤곤(Yun-Gon Kim),임춘규(Chun-Kyoo Lim),이춘곤(Chun-Kon Lee),권영신(Yung-Shin Kwon) 한국산업융합학회 2007 한국산업융합학회 논문집 Vol.10 No.4
Most of the fatigue fractures of various machine structures start at discontinuities or small defects. In this study property of crack growth of titanium alloy was also analyzed to investigate the difference compared with the carbon steel. Titanium alloy has very high specific strength, and the material is widely utilized in advanced engineering fields such as aerospace, atomic energy and ocean development because of its excellence in corrosion and heat resistance. Generally the machine structures experience irregular loadings rather than periodic forces. The prediction of the fatigue life therefore has been analyzed to provide fundamentals of the design and estimation of the machine structures under irregular loading conditions.
Primaquine 복용 후 발생한 메트헤모글로빈혈증 1예
이재용 ( Jae Yong Lee ),김성한 ( Sung-han Kim ),안수종 ( Sujong An ),오혜선 ( Hye-seon Oh ),이상영 ( Sang Young Yi ),이훈희 ( Hoon Hee Lee ),한덕종 ( Duck Jong Han ) 대한내과학회 2017 대한내과학회지 Vol.92 No.1
Primaquine은 말라리아 치료제로써 널리 사용되고 있으며, 주폐포자충 폐렴 치료제로써 clindamycin과 병합하여 사용되고 있다. Primaquine의 다양한 부작용은 많은 보고를 통해 알려져 있으며, 메트헤모글로빈혈증은 primaquine의 드문 부작용 중 하나이다. 메트헤모글로빈혈증은 임상 증상 및 검사소견으로 의심할 수 있으며, 이를 확진하기 위해서는 특별한 진단적 접근이 이뤄져야 한다. 저자들은 주폐포자충 폐렴을 치료하기 위해 표준용량의 primaquine을 복용한 후 청색증을 동반한 메트헤모글로빈혈증이 발생한 증례를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Primaquine is often administered for the hypnozoite stage of Plasmodium vivax and Plasmodium ovale. Primaquine (with clindamycin) is also an alternative drug for treatment of pneumocystis pneumonia when trimethoprim/sulfamethoxazole cannot be used. Primaquine may cause methemoglobinemia, an altered state of hemoglobin in which the ferrous state of heme is oxidized to the ferric state. We report a case of methemoglobinemia caused by a standard dose of primaquine plus clindamycin in a 27-year-old female recipient of a kidney transplant who was diagnosed with pneumocystis pneumonia. (Korean J Med 2017;92:94-98)
피치가 다른 다축 태핑에서의 가공 특성과 품질 평가에 관한 연구
이종형 ( Jong-hyung Lee ),이창헌 ( Chang-heon Yi ),김영문 ( Young-moon Kim ),이상영 ( Sang-young Lee ),이상중 ( Sang-joong Lee ) 한국산업융합학회 2006 한국산업융합학회 논문집 Vol.9 No.4
As the products such as HDD, Notebook, PDA, and Mobile Phone become smaller and thinner, the radius of threads as well as holes for assembling those products become smaller, even down to 1mm. To produce such small holes and thread efficiently, multi tapping is highly necessitated. However the multi tapping characteristics is not well known because its complicated cutting mechanism and thus the quality of the produced holes and threads is not well studied yet. In this paper, experiments have been conducted for small-radius threads using M2 and M2.6 and M3 cold forming tap to investigate multi tapping process using several useful signal such as torque and Z-axis encoder pulse. The surface and profile of the machined threads have been magnified and observed through a SEM