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이상룡,허근섭,강오현,이춘영,Lee, Sang-Ryong,Heo, Geun-Sub,Kang, Oh-Hyun,Lee, Choon-Young 제어로봇시스템학회 2011 제어·로봇·시스템학회 논문지 Vol.17 No.3
In this paper, we proposed a technique to recognize three states in stance phase of gait cycle. Walking assistive devices are used to help the elderly people walk or to monitor walking behavior of the disabled persons. For the effective assistance, they adopt an intelligent sensor system to understand user's current state in walking. There are three states in stance phase; Loading Response, Midstance, and Terminal Stance. We developed a foot pressure sensor using 24 FSRs (Force Sensing/Sensitive Resistors). The foot pressure patterns were integrated through the interpolation of FSR cell array. The pressure patterns were processed to get the trajectories of COM (Center of Mass). Using the trajectories of COM of foot pressure, we can recognize the three states of stance phase. The experimental results show the effective recognition of stance phase and the possibility of usage on the walking assistive device for better control and/or foot pressure monitoring.
온담탕합총명탕(溫膽湯合聰明湯) 열수추출물과 초미세분말이 cytokine과 건망증 생쥐모델 기억력감퇴에 미치는 영향
장영주 ( Young Joo Jang ),정인철 ( In Chul Jung ),이상룡 ( Sang Ryong Lee ) 대한한방신경정신과학회 2009 동의신경정신과학회지 Vol.20 No.1
Objectives: This experiment was designed to investigate the effect of the ODTCMT hot water extract & ultra-fine Powder on Alzheimer`s Disease Model Induced by βA. Methods: The effects of the ODTCMT hot water extract on expression of IL-1β, IL-6, TNF-α in BV2 microglial cell line treated by lipopolysacchaide(LPS) were investigated. The effects of the ODTCMT hot water extract & ultra-fine powder on the behavior of the memory deficit mice induced by scopolamine were investigated. Results: 1. The ODTCMT hot water extract significantly suppressed the production of TNF-α, IL-6 and IL-1β in BV2 microglial cell line treated with LPS. 2. The ODTCMT hot water extract & ultra-fine powder groups showed significantly inhibitory effect on the scopolamine-induced impairment of memory in the experiment of Morris water maze. Conclusions: These results suggest that the ODTCMT hot water extract & ultra-fine powder may be effective for the prevention and treatment of Alzheimer`s disease. Investigation into the clinical use of the ODTCMT hot water extract & ultra-fine powder for Alzheimer`s disease is suggested for future research.
김영조(Young Jo Kim),정영기(Young Ki Chung),이병욱(Byung Wook Lee),이상룡(Sang Ryong Lee),최동준(dong Joon choi) 대한소화기학회 1986 대한소화기학회지 Vol.18 No.2
A clinical analysis ivas carried out on 46 cases of pyloric channel ulcers collected from 4,565 persons who had taken gastrofiberscopic examinations from Maich, 1981 to Fchruary, 1986 at the 1)Department of Internal Medicine in the Maryknoll hospital. The results obtained were as follows: 1) Pyloric channel ulcer devloped in 3.8% of incidence from all cases of peptic ulcer. 2) The male to female ratio was 2.5:1. Those in the 4th decades were the most frequently observed age group and the average was 46.2 years of age. 3) The most frequent complaint was upper ahdominal pain with a rate of 69.6% and the next came indigestion, nausea and vomiting, belching, bloating in order. weight loss was in minority (10.9). 4) The most common site of channel ulcer vas anterior wall with a rate of 59.5% and the frequency of the other sites were lesser curvature, greater curvature, posterior wall in order. 5) Considering the healing process of ulcer, the most frequent stage was active stage, the next came healing and scarring stage in order. 6) The longitudinal diameter of active channel ulcer was below 5mm with 68.8% of incidence and almost ones were l0mm or less. The majority of those were round shape. 7) In 45.7% of all cases the channel ulcer did not cambine ulcers on the other sites and 37.0% of the channel ulcers combined gastric ulcer.
배기만,이상룡,이상일,이춘영,Bae, Ki-Man,Lee, Sang-Ryong,Lee, Sang-il,Lee, Choon-Young 대한임베디드공학회 2008 대한임베디드공학회논문지 Vol.3 No.2
The pipes have been laid underground while the industry is developing. We have to take maintenance procedure when the pipes are cracked or ruptured. It is very difficult jop to check pipe's crack because the pipes are narrow and laid underground. Using in-pipe robot, we can check the conditions of inner section of pipes, therefore, we designed a crawler type robot to search cracked pipe. In this paper, we have made a special focus on the control of the robot using differential drive algorithm to move in curved section of pipes. The detailed design of the robot with experimental result show the effectiveness of the robot in pipe maintenance.
인삼양영탕(人蔘養榮湯)이 Aβ를 처리한 PC12 세포와 생쥐의 손상 뇌신경조직에 미치는 영향
장영주 ( Young Joo Jang ),정인철 ( In Chul Jung ),이상룡 ( Sang Ryong Lee ) 대한한방신경정신과학회 2010 동의신경정신과학회지 Vol.21 No.1
Objectives: This experiment was designed to investigate the effect of the InSamYangYoung-tang(Renshenyangrongtang) extract on Aβ-induced AD model. Methods: The effects of the InSamYangYoung-tang(Renshenyangrongtang) extract on neural damages of cultured PC12 cells induced by Aβ were investigated. The effects of the InSamYangYoung-tang(Renshenyangrongtang) extract on neural damages of hippocampal and cortical neurons in the mouse induced by β-amyloid were investigated. Results: 1. Aβ treatment into neuronal cells activated cell death pathway when analyzed by MTT assay and by histological analysis. Then InSamYangYoung-tang(Renshenyangrongtang) treatment improved cell survival to a similar level as in normal group. 2. Aβ treatment increased caspase 3 protein levels but decreased phospho-Erk1/2 in neuronal cells. InSamYangYoung-tang (Renshenyangrongtang) treatment reversed the production levels of two proteins close to those in normal group. 3. Aβ treatment induced the atrophy of neuronal cells in terms of neuronal processes and cell body shrinkage, but InSamYangYoung-tang(Renshenyangrongtang) greatly improved their morphology. 4. Neuroprotective activity, as observed in InSamYangYoung-tang(Renshenyangrongtang)-treated groups, was similarly observed in cells treated with galantamine which was used as a positive control. Moreover, overall recovery pattern by InSamYangYoung-tang(Renshenyangrongtang) was similar between cultured PC12 cells and in vivo hippocampal and cerebral cortical neurons in the mouse brain. Conclusions: This experiment shows that the InSamYangYoung-tang(Renshenyangrongtang) may play a protective role in neural tissues damaged by cytotoxic substances. Since neuronal damage seen in degenerative brains such as AD are largely unknown, the current data may provide possible insight into therapeutic strategies for AD treatments. InSamYangYoung-tang(Renshenyangrongtang) might be effective for the treatment of AD. Investigation into the clinical use of the InSamYangYoung-tang(Renshenyangrongtang) for AD is suggested for future research.
간장 및 담도 : Halothane 마취후 발생한 급성 간염 3예
김영조(Young Jo Kim),정영기(Young Ki Chung),이병욱(Byung Wook Lee),이상룡(Sang Ryong Lee),최동준(dong Joon choi),서동룡(Dong Ryong Seo) 대한소화기학회 1986 대한소화기학회지 Vol.18 No.1
N/A We report 3 cases of acute hepatitis following halothane anesthesia. Case 1 is a 30 year old woman who had a subtotal gastrectomy under halothane anesthesia. Ten days after anesthesia she became febrile without evidence of infection. Jaundice was noticed 14 days after anesthesia and the serum transaminase levels were markedly elevated. The serologic tests for viral hepatitis were all negative. After treatment with corticosteroids the hepatic function had improved. Case 2 is a 47 year old man who underwent a subtotal gastrectomy under halothane znesthesia. Fever appeared 10 days after anesthesia and jvndice was noticed 3 days later. The serum transaminase levels were high and prothrombin time was greatly prolonged. Despite steroid therapy he died of hepatic failure 18 days after anestheia. A liver biopsy was performed and the specimen showed extensive hepatic necrosis and cholestasis. Case 3 is a 29 year old man who underwent osteotomy and bone graft under halothane anesthesia. Nine days after anesthesia he became febrile and his whole body was covered by a rash. The serum bilirubin and transaminase levels were high. He was treated with corticosteroids under the diagnosis of halothane hepatitis and the hepatic funiction had I mproved.