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RISS 인기검색어
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- 저자 : 윤원찬 ( Won-chan Yoon ) (검색결과 3 건)
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메트로놈을 이용한 트레드밀 보행훈련이 보행패턴에 미치는 영향
윤원찬 ( Won-chan Yoon ),박선욱 ( Sun-wook Park ) 대한물리의학회 2020 대한물리의학회지 Vol.15 No.2
PURPOSE: The purpose of this study was to investigate the effect of treadmill walking training using the metronome on the gait pattern. METHODS: A total of 33 healthy persons were studied consisting of 17 female and 16 male in the 20-30 age group. A gait analysis program was installed on a treadmill with a built - in gait analysis sensor and laptop. After 9 minutes of treadmill walking, gait analysis was performed for 1 minute. The mean values of the differences in the step length, angle of COP, separation line standard deviation and step force of the lower legs affecting walking symmetry were calculated for treadmill walking and treadmill walking using the metronome. The Shapiro-Wilk test was used to test the normality of the collected data and a paired t-test was performed to analyze the difference in walking before and after using the metronome. RESULTS: As a result of the analysis, the mean of difference between the measured values of the bilateral lower extremity for step length, angle of COP, separation line standard deviation and step force were statistically significant before and after treadmill walking using the metronome. CONCLUSION: Therefore, the treadmill walking training using the metronome is effective in decreasing the difference in the foot width, gait angle, gait distribution, and foot pressure. Because of this, the treadmill walking training using the metronome has a significant effect on walking symmetry among the elements for correct walking, which is a means for enabling efficient and continuous walking.
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전신성 홍반성 루푸스 환자에서 Total Anti-oxidant Capacity와 질병활성도의 상관성
정원태 ( Won Tae Chung ),이성원 ( Sung Won Lee ),김경희 ( Kyung Hi Kim ),김정만 ( Jung Man Kim ),김채기 ( Chae Gi Kim ),윤원찬 ( Wern Chan Yoon ),류재근 ( Jae Kean Ryu ),장성국 ( Sung Gug Chang ),송용호 ( Yong Ho Song ),최정윤 ( J 대한류마티스학회 2001 대한류마티스학회지 Vol.8 No.3
Objective: To determine the correlation between total anti-oxidant capacity (TAOC) and lipid peroxidase (LPO) levels in serum and disease activity in systemic lupus erythematosus (SLE). Methods: The study population consisted of 99 patients with SLE according to the 1982 revised ACR criteria and 83 healthy controls. The serum TAOC levels in 99 patients with SLE and 83 healthy controls by the ABTS(R) inhibition method (Randox Ltd, Antrim, UK) and serum malondialdehyde (MDA) levels in 37 out of 99 patients with SLE were measured. Anti-dsDNA antibody (anti-dsDNA), albumin, AST, ALT, cholesterol, uric acid and creatinine were measured to determine the association with the serum TAOC levels. The correlation between the serum TAOC levels and nephritis in 27 cases with nephritis out of 99 SLE patients was also investigated. The SLE disease activity was determined by the SLE disease activity index (SLEDAI) at the time of sample collection. Results: Compared to the controls (1.37±0.127mmol/L), serum TAOC levels were significantly decreased (1.29±0.124mmol/L) in SLE patients (p=0.001). And there was a negative correlation between serum TAOC levels and SLEDAI total scores in the SLE patients (r=-0.388, p=0.0001), but no significant correlation between TAOC levels and C3 and anti-dsDNA. Further, a significant difference (p<0.04) in TAOC levels was found in SLE patients with and without nephritis. In comparison with other parameters such as AST, ALT, and cholesterol which might change anti-oxidant level, there was no correlation between the serum TAOC levels and them, except for serum uric acid (r=0.387, p=0.0001), creatinine, and albumin (r=0.507, p=0.0001). Additionally, we couldn`t find significant correlation between the serum TAOC levels and MDA. Conclusions: The serum TAOC levels correlate significantly with SLE disease activity and are associated with nephritis. Also, this study showed a significant correlation with serum albumin levels in these patients. Conclusively, the measurement of the serum TAOC levels in patients with SLE will provide useful information on SLE disease activity.
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db/db마우스에서 Aspergillus awamori로 발효한 황기 추출물의 항당뇨 및 지질개선 효능
이은정(Eun Jung Lee),최활(Hwal Choi),윤원찬(Won Chan Yoon),김영수(Young Soo Kim),송빛나(Bit Na Song),이미연(Mi Yeon Lee),박보람(Bo Ram Park),이성현(Sung Hyen Lee),최지호(Ji Ho Choi),박신영(Shin Young Park) 한국약용작물학회 2021 한국약용작물학회지 Vol.29 No.4
Background: This study investigated the anti-diabetic effects of Astragalus membranaceus (Fisch.) Bunge fermented by Aspergillus awarmori in db/db mice. Methods and Results: Astragalus membranaceus roots were fermented with A. awarmori for 4 days and extracted with hot water. The male mice were divided into five groups: db/m (non-diabetic db/+mice), db/db (C57BLKs/J db/db mice), MT (db/db + 1% metformin), AM (db/db + 1% A. membranaceus extract), and FAM (db/db + 1% fermented A. membranaceus extract). After 10 weeks of treatment, we measured the body weight, food intake, and blood glucose, hemoglobin A1C (HbA1c), plasma insulin, adiponectin, and transaminase levels. Oral glucose tolerance test was performed and serum lipid profile was determined. As expected, the AM and FAM groups had significantly reduced body weight, fasting glucose, lipid content, and HbA1c, transaminase, and serum insulin levels, and increased serum adiponectin levels. Conclusions: Therefore, based on these research results, A. membranaceus extract and fermented A. membranaceus extract can be used to prevent and treat type 2 diabetes by reducing blood glucose levels and lipid content.
ScienceON
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