http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
임상 : 새롭게 진단받은 교모세포종 환자의 치료에서 TMZ와 BCNU사용의 비교 분석
윤동주 ( Dong Ju Yun ),김형동 ( Hyung Dong Kim ),김기욱 ( Ki Uk Kim ),송영진 ( Young Jin Song ),안상석 ( Sang Soak Ahn ) 대한뇌종양학회 2011 대한뇌종양학회지 Vol.10 No.1
Background: Since 2005, temozolomide (TMZ) has replaced BCNU as a standard initial chemotherapeutic agent for glioblastoma multiforme (GBM) treatment. Few articles, however, have compared BCNU and TMZ as concomitant and/or adjuvant chemotherapeutic agents. We studied a retrospective analysis comparing BCNU plus radiotherapy (RT) with TMZ plus RT on patients who were diagnosed with primary GBM in the past 14 years at the our hospital. Patients and Methods: Seventy-four patients (≥14 years) who had been treated for histologically confirmed GBM between January 1995 and December 2008 at our hospital were included in this study. Of the 74 patients, 20 patients who had received BCNU plus RT, and 34 patients who had received TMZ plus RT, were included in this study. Overall survival (OS) and progression free survival (PFS) versus the type of chemotherapy was analyzed. Result: On univariate analysis, median OS in the BCNU group and TMZ group were 10 and 16 months respectively. However, the curves were significantly different (p=0.044). On multivariate analysis, it was not significant (HR=1.121, 95% CI, 0.513-2.451 ; p=0.775). The median PFS was 8 months equally and the curves were not significantly different (p=0.461) on univariate analysis. It was also not significant on multivariate analysis (HR=0.716, 95% CI, 0.341-1.501 ; p=0.376). Conclusion: The effectiveness of the BCNU and TMZ did not have a statistically significant difference in terms of the patients` survival rate and tumor progression. Because TMZ is less toxic than BCNU and the modalities of administra-tion of TMZ are more easeful than those of BCNU, TMZ could be the more preferred chemotherapy agent.
윤재식,박형호,배인성,이상백,윤동주,김병일,Yun, Jae-Sik,Park, Hyeong-Ho,Bae, In-Seong,Lee, Sang-Baek,Yun, Dong-Ju,Kim, Byeong-Il 한국재료학회 2001 한국재료학회지 Vol.11 No.12
Purity tantalum powder has been produced by sodium reduction of potassium tantalum fluoride($K_2TaF_7$)in a stainless steel bomb. The influence of experimental variable, such as excess of reductant and temperature of reduction on the yield and quality of the Ta powder has been studied. The excesses of reductant were varied from -20%, -10%, 0%, 5%, 10%, 20%. When -20% excess of sodium was used, the un-reacted sodium remained in the reacted product. The yield of 81% of Ta powder has been achieved by reducing 50g of$K_TaF_7$with 5% sodium in excess of stoichiometric amount in presence of 16.8g of sodium chloride in the charge at a reduction temperature of$905{\circ}C$. The proportion of fine fraction(~325mesh) decreased appreciably with the increase of sodium excess, and the yield of tantalum powder improved from 65% to 94%. The average particle size of Ta Powder is improved from 3 microns to 4 microns in the 5% excess sodium.
포스트텐션 콘크리트 포장의 두께에 따른 긴장 설계 비교 검토
윤동주 慶熙大學校 大學院 2009 高凰論集 Vol.44 No.-
본 논문은 포스트 텐션 콘크리트 포장(PTCP : Post-Tensioned Concrete Pavement)의 종방향 긴장 설계에 있어서 슬래브 두께의 영향을 비교 검토하기 위하여 수행되었다. 우선 현실적으로 가능한 최소 PTCP 슬래브 두께를 15cm로 하여 종방향 긴장 설계를 수행 할 수 있다. 그리고 슬래브 두께가 20cm, 25cm일 때 동일한 과정을 거쳐 종방향 긴장설계를 수행하여 긴장량을 비교 검토하였다. 분석 결과 차륜하중에 의해 슬래브에 발생하는 응력은 슬래브 두께가 증가 할수록 감소하였으나 환경하중에 의한 슬래브의 컬링 응력은 슬래브 두께가 증가 할수록 증가하였다. 이는 동일한 온도구배를 가정하였을 때 슬래브 두께가 증가 할수록 슬래브 상·하부의 온도차이가 크게 발생하기 때문이다. 따라서 슬래브에 발생하는 최대 인장응력은 슬래브 두께가 증가 할수록 큰 차이가 발생하지 않는 것을 알 수 있다. 이를 이용하여 종방향 긴장 설계를 수행하면 슬래브 두께가 증가 할수록 긴장 단면적이 커지게 되어 긴장에 필요한 강선의 개수가 증가하게 된다. 결국 필요한 긴장응력이 비슷하더라도 긴장 단면적이 넓어짐에 따라 그만큼 많은 강선을 사용하여 긴장응력을 가하게 된다.· This study presents the effect of the slab thickness on the design of longitudinal post tensioning for Post-Tensioned Concrete Pavement(PTCP). First, the longitudinal tensioning design was carried out with the actual minimum thickness of 15cm. Then, all the tensile stresses were investigated with the same process for the thicknesses of 20cm and 25cm. The results of this analysis showed that as the thickness of a slab increased, the stresses caused by vehicle loads decreased, but the curling stresses caused by environmental loads the increased. That happened because the differences in temperature between the upper part and the lower part of the slab increased along with the thickness include since the temperature gradient was assured to be constant. Therefore, there was no big differences in the maximum tensile stresses to a slab as the thickness of the slab becomes larger. Using these results, to perform a longitudinal post tensioning design, more tendons should be needed for a large thickness because fhe prestressing area becomes larger. Even though there are similar tensile stresses, more tendons are needed to give more tensile forces because of the slab increasement of the area.