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림프절의 염증성 가성 종양 - 세침흡인 세포학적 소견 1예 보고 -
박소영,공경엽,허주령,유은실,이인철,김온자,Park, So-Young,Gong, Gyung-Yub,Huh, Joo-Ryung,Yu, Eun-Sil,Lee, In-Chul,Kim, On-Ja 대한세포병리학회 1997 대한세포병리학회지 Vol.8 No.1
Reports on the cytologic or histopathologic findings of inflammatory pseudotumors are relatively infrequent and most of them have dealt with those involving the lung, liver, genitourinary tract, alimentary tract, spleen, mediastinum, retroperitoneum, etc. Moreover there have not been any cytologic studios of those involving lymph nodes. We present fine needle aspiration cytologic features of inflammatory pseudotumor occurring in a lymph node in a 64 year-old man. The aspirate consisted of proliferating spindle cells and admixed histiocytes, fibroblasts, lymphocytes, and plasma cells. Histiocytes were present either singly or in loosely cohesive small clusters. A few multinucleated giant cells were present as well. However, tuberculosis could be excluded by the absence of typical granuloma, caseation necrosis, or characteristic mixed spindle and inflammatory cell components. Other benign and malignant lymphadenopathies could also be differentiated based on cytologic findings.
세침흡인 검사물을 이용한 유방암세포 에스트로젠수용체 분석 : 동결절편조직과의 비교
공경엽,안세현,박건춘,최기영,유은실,이인철,Gong, Gyung-Yub,Ahn, Se-Hyun,Park, Kun-Choon,Choe, Ghee-Young,Yu, Eun-Sil,Lee, In-Chul 대한세포병리학회 1994 대한세포병리학회지 Vol.5 No.1
The expression of sex steroid hormone receptors by neoplastic cells is an important predictor of response to hormone therapy. Thus, the selection of treatment modality is often based on the identification of receptors in tumor tissue. Various monoclonal antibodies of high specificity are now available for analyzing the estrogen receptor (ER). With these antibodies, biochemical enzyme immunoassay and immunohistochemistry using histologic sections have been used for ER analysis. We used fine needle aspirates from 15 human primary breast carinomas for the analysis of ERs. The semiquantitative receptor values obtained in cytologic specimens were correlated well with those from histologic specimens. The results of ER in fine needle aspirates were concordant with ER in histologic specimens(r=0.94). Only three cases showed a little difference in staining intensity and proportion of positive cells. Our results showed a good correlation between the receptor values determined in cytologic smears and those determined in tissue sections. It is suggested that measurement of the ER in cytologic smears may be a reliable technique which can be performed on aspiration cytologic samples.
다양한 조직학적 소견을 보이는 간의 혈관근지방종: 간세포암종 혹은 염증성 거짓종양과 유사한 8예
황일선 ( Ii Seon Hwang ),유은실 ( Eun Sil Yu ),조경자 ( Kyung Ja Cho ) 대한소화기학회 2012 대한소화기학회지 Vol.60 No.4
Background/Aims: Hepatic angiomyolipoma (AML) is a rare mesenchymal tumor of the liver and demonstrates a marked histologic diversity. HMB-45 is a promising immunomarker for this tumor and especially helpful to diagnosis of some AMLs with unusual morphology. The purpose of this study was to better define the variable histologic feature of hepatic AML. Methods: Eight hepatic AMLs were examined, and all of that were resection specimens. The diagnosis was confirmed by the presence of HMB-45 positive cells. Median age was 41.5 years old, and mean size of tumor was 8.94 cm. Results: Conventional mixed type was 5 cases which showed myomatous, angiomatous and lipomatous component, and 3 cases were myomatous predominant. Variable patterns including spider web cell morphology, solid sheet-like and trabecular pattern were identified on myomatous component and variable amount and patterns of inflammatory cell infiltration was identified. Conclusions: With only histologic features, it is difficult to distinguish hepatic AML from other hepatic tumor including hepatocellular carcinoma or inflammatory pseudotumor. A correct diagnosis of hepatic AML is possible by a close histologic examination with immunohistochemical stainings such as HMB-45 which is important to patient`s prognosis.